Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_3601
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Entry
ERDMAN_3601 CDS
T02526
Symbol
accA3
Name
(GenBank) bifunctional acetyl-/propionyl-coenzyme Acarboxylase subunit alpha
KO
K11263
acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:
6.4.1.2
6.4.1.3
6.4.1.-
6.3.4.14
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00061
Fatty acid biosynthesis
mtn00074
Mycolic acid biosynthesis
mtn00280
Valine, leucine and isoleucine degradation
mtn00620
Pyruvate metabolism
mtn00630
Glyoxylate and dicarboxylate metabolism
mtn00640
Propanoate metabolism
mtn01100
Metabolic pathways
mtn01110
Biosynthesis of secondary metabolites
mtn01120
Microbial metabolism in diverse environments
mtn01200
Carbon metabolism
mtn01212
Fatty acid metabolism
Module
mtn_M00082
Fatty acid biosynthesis, initiation
mtn_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
mtn_M00887
Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ERDMAN_3601 (accA3)
00630 Glyoxylate and dicarboxylate metabolism
ERDMAN_3601 (accA3)
00640 Propanoate metabolism
ERDMAN_3601 (accA3)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
ERDMAN_3601 (accA3)
00074 Mycolic acid biosynthesis
ERDMAN_3601 (accA3)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ERDMAN_3601 (accA3)
Enzymes [BR:
mtn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
ERDMAN_3601 (accA3)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
ERDMAN_3601 (accA3)
6.4.1.3 propionyl-CoA carboxylase
ERDMAN_3601 (accA3)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Biotin_lipoyl_2
Dala_Dala_lig_C
Phage_cement_2
LAL_C2
Peptidase_M23
Motif
Other DBs
NCBI-ProteinID:
BAL67375
UniProt:
A0A0H3LE85
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All DBs
Position
3651678..3653480
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AA seq
600 aa
AA seq
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MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFA
LGGQTSAESYLDFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSI
RDLGDKVTARHIAARAQAPLVPGTPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKV
ARTIDEIPELYESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCS
LQRRYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVN
TRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHAIEFRINGEDAGRNFLPA
PGPVTKFHPPSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFG
VEGLATVIPFHRAVVSDPAFIGDANGFSVHTRWIETEWNNTIEPFTDGEPLDEDARPRQK
VVVEIDGRRVEVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
TVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAITQGTVLAEIK
NT seq
1803 nt
NT seq
+upstream
nt +downstream
nt
gtggctagtcacgccggctcgaggatcgctcggatctctaaggttctcgtcgccaatcgc
ggcgagatcgcagtgcgggtgatccgggcggcccgcgacgccggcctgcccagcgtggcg
gtgtacgccgaacccgacgccgagtccccgcatgttcggctggccgacgaggcgttcgcg
ctgggcggccagacctcggcggagtcctatctggacttcgccaagatcctcgacgcggca
gccaagtccggggccaacgccatccaccccggctacggcttcctagcggaaaatgccgac
ttcgcccaggcggtgatcgacgccggcctgatctggatcggccccagcccgcagtcgatc
cgcgacctgggcgacaaggtcacggcccgtcacatcgcggcccgcgctcaggcgcccctg
gtgccgggtacccccgatccggtcaaaggcgccgacgaggtggtggcattcgccgaggag
tacggcctgccgatcgcgatcaaggccgcccacggcggcggcggcaagggcatgaaggtg
gcccgcaccatcgacgagattccggagctgtacgagtcggcggtgcgcgaggccacggcc
gcgttcggccgcggtgagtgctacgtggagcgctatctcgacaagccgcgccacgtcgaa
gcacaggtgatcgccgaccagcacggcaacgtcgtcgtcgccggcacccgggactgctcg
ctgcagcgccgctaccagaagctggtcgaggaggcgcccgcaccgttcctgaccgacttt
caacgcaaagagatccacgactcggccaaacggatttgcaaagaggcccattaccacggc
gccggcaccgtcgaatacctggtcggtcaggacggcttgatctcgttcttggaggtcaac
acgcgccttcaggtagaacacccggtcaccgaggaaaccgcgggcatcgacttggtgctg
cagcaattccggatcgccaacggcgaaaagctggacatcaccgaggatcccaccccgcgc
gggcacgccatcgaattccggatcaacggcgaggacgcggggcgtaacttcctaccggcg
cccgggccggtgacaaagttccacccgccgtccggccccggtgtgcgggtggactccggt
gtcgagaccggctcggtgatcggcggccagttcgactcgatgctggccaagctgatcgtg
cacggtgccgaccgcgccgaggcgctggcgcgggcccggcgcgcgctgaacgagttcggt
gtcgaaggcctggcgacggtcatcccgtttcaccgcgccgtggtgtccgacccggcattc
atcggcgacgcgaacggcttttcggtacatacccgctggatcgagaccgagtggaataac
accatcgagccctttaccgacggcgaacctctcgacgaggacgcccggccgcgtcagaag
gtggtcgtcgaaatcgacggtcgccgcgtcgaagtctcgctgccggctgatctcgcgctg
tccaatggcggcggttgcgacccggtcggtgtcatccggcgcaagcccaagccgcgcaag
cggggtgcgcacaccggcgcggcggcctccggtgacgcggtgaccgcgcctatgcagggc
accgtagttaagttcgcggtcgaagaagggcaagaggtcgtggccggcgacctagtggtg
gtcctcgaggcgatgaagatggaaaacccggtcaccgcgcataaggatggcaccatcacc
gggctggcggtcgaggcgggcgcggccatcacccagggcacggtgctcgccgagatcaag
taa
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