Mycobacterium tuberculosis CTRI-2: MTCTRI2_0436
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Entry
MTCTRI2_0436 CDS
T01993
Name
(GenBank) carboxylate-amine ligase
KO
K06048
glutamate---cysteine ligase / carboxylate-amine ligase [EC:
6.3.2.2
6.3.-.-]
Organism
mto
Mycobacterium tuberculosis CTRI-2
Pathway
mto00480
Glutathione metabolism
mto01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
mto00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MTCTRI2_0436
Enzymes [BR:
mto01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
MTCTRI2_0436
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AEM98879
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Position
520044..521174
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AA seq
376 aa
AA seq
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MPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN
TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA
ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG
YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE
VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV
IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD
GDLRAVVDALVAELVI
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
ttgcctgcccgcaggtcggccgcccgaattgatttcgcaggctcaccgcggcccaccctc
ggtgtggagtgggagttcgcgctcgttgactcgcagacccgcgatctgagcaatgaagcc
accgcggttatcgccgaaatcggcgaaaacccgcgggtccacaaggaattgctgcgcaac
accgtagagattgtcagcggtatctgcgaatgtaccgccgaggcaatgcaggatctgcgc
gataccctgggccccgcccgtcagatcgtgcgcgaccgcgggatggagctgttctgcgcg
ggtacccaccccttcgcgcggtggtcggcccagaagctcaccgacgcgccgcggtacgcg
gagctgatcaaacgcacccagtggtggggccggcagatgctgatctggggtgtacacgtg
catgtcgggattcgctcggcgcacaaagtgatgccgatcatgacgtcgctgctcaactac
tacccgcatctgttggcgctctcggcctcatcaccctggtggggtggcgaagacaccggg
tatgccagcaaccgggcgatgatgttccagcagttgcccaccgccgggctgccgtttcac
tttcagaggtgggcggagttcgaaggtttcgtgtacgaccagaagaagaccggcatcatc
gaccatatggacgaaatccgttgggatataagaccctcaccccatctgggcaccctggag
gtgcggatctgcgatggcgtgtccaacctacgagagctcggcgcgctggtcgcgctgacg
cattgcctgatcgtcgatctggaccgccgcttggacgccggcgaaacgctaccgaccatg
cctccctggcacgtccaggagaacaagtggcgtgccgcccgctacggcctggacgcggtg
atcatcttggacgccgacagcaacgaacggctggttaccgatgacctcgcggatgtgctg
acccggctggagccggtcgccaagtcgctgaactgtgccgacgagcttgccgcggtctcc
gatatctaccgcgatggcgcctcctaccagcggcagctgcgagtggcgcagcagcatgac
ggcgatttgcgcgcggtagttgacgcgctggttgccgagctggtgatttag
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