KEGG   Mycobacterium tuberculosis CTRI-2: MTCTRI2_3429
Entry
MTCTRI2_3429      CDS       T01993                                 
Symbol
folD
Name
(GenBank) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
mto  Mycobacterium tuberculosis CTRI-2
Pathway
mto00670  One carbon pool by folate
mto00720  Other carbon fixation pathways
mto01100  Metabolic pathways
mto01120  Microbial metabolism in diverse environments
mto01200  Carbon metabolism
mto01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:mto00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    MTCTRI2_3429 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MTCTRI2_3429 (folD)
Enzymes [BR:mto01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     MTCTRI2_3429 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     MTCTRI2_3429 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall
Other DBs
NCBI-ProteinID: AEN01828
LinkDB
Position
complement(3768218..3769063)
AA seq 281 aa
MGAIMLDGKATRDEIFGDLKQRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKV
GITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDAD
GLHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTR
RSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGL
VGDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR
NT seq 846 nt   +upstreamnt  +downstreamnt
gtgggcgcgatcatgctggacggcaaggctacccgcgacgagatcttcggtgacctcaag
cagcgggtggccgcattggacgcggcgggccgcacgcccggcttgggcaccatcctggtc
ggtgacgacccggggtcgcaggcctacgtgcgcggtaagcacgctgattgcgccaaggtg
ggcatcacgtcgattcgccgcgacctgcccgccgacatcagcaccgccacgctgaatgag
accatcgacgaactgaacgccaaccccgactgcaccggctacatcgtgcagttgccgttg
cccaagcatctcgacgagaacgcggcgttggagcgcgtcgacccggccaaggacgccgat
gggttgcacccgaccaacctgggccggctggtgctgggcaccccggcgccgctgccgtgt
actccgcgcggcattgtgcacctgctgcggcgctacgacatctcgatcgccggcgcgcat
gtggtcgttatcggtcgtggtgtgacggtgggccggccgctggggctgttgctgacccgg
cgctcggagaatgccacggtgacgttgtgccacaccggtacccgcgacctgcccgcgttg
acccggcaggccgacatcgtcgtggccgcggtcggggtggcgcacctgttgacggctgac
atggtgcgcccgggtgccgcggtaatcgacgtcggcgtcagccgcactgatgacggactg
gtcggcgacgtgcatcccgatgtgtgggagctcgccggccacgtgtcacccaatccgggc
ggcgtgggcccgttgacccgggcgttcttgttgaccaatgtcgtggagctggctgagcgg
cgatga

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