Mycobacterium tuberculosis H37Rv: Rv0334
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Entry
Rv0334 CDS
T00015
Symbol
rmlA
Name
(RefSeq) glucose-1-phosphate thymidylyltransferase
KO
K00973
glucose-1-phosphate thymidylyltransferase [EC:
2.7.7.24
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00520
Amino sugar and nucleotide sugar metabolism
mtu00521
Streptomycin biosynthesis
mtu00523
Polyketide sugar unit biosynthesis
mtu00525
Acarbose and validamycin biosynthesis
mtu00541
Biosynthesis of various nucleotide sugars
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
mtu01250
Biosynthesis of nucleotide sugars
Module
mtu_M00793
dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
Rv0334 (rmlA)
00541 Biosynthesis of various nucleotide sugars
Rv0334 (rmlA)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
Rv0334 (rmlA)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
Rv0334 (rmlA)
00525 Acarbose and validamycin biosynthesis
Rv0334 (rmlA)
Enzymes [BR:
mtu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.24 glucose-1-phosphate thymidylyltransferase
Rv0334 (rmlA)
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Motif
Pfam:
NTP_transferase
NTP_transf_3
Motif
Other DBs
NCBI-GeneID:
886568
NCBI-ProteinID:
NP_214848
TubercuList:
Rv0334
UniProt:
P9WH13
Structure
PDB
PDBj
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Position
398658..399524
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AA seq
288 aa
AA seq
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MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQLITTPHDAPG
FHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGADSVALVLGDNIFYGPGLGTSL
KRFQSISGGAIFAYWVANPSAYGVVEFGAEGMALSLEEKPVTPKSNYAVPGLYFYDNDVI
EIARGLKKSARGEYEITEVNQVYLNQGRLAVEVLARGTAWLDTGTFDSLLDAADFVRTLE
RRQGLKVSIPEEVAWRMGWIDDEQLVQRARALVKSGYGNYLLELLERN
NT seq
867 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgggatcatcttggccggcggttcgggcacccggctgtacccgatcaccatgggg
atcagcaagcagctgctgccggtctacgacaaaccgatgatctactacccgctcaccacg
ctgatgatggctgggatccgagacattcagttgatcaccaccccgcatgacgcgcccggc
tttcatcgactcctgggcgacggcgcgcacttgggagtgaacatcagctacgccacccag
gatcagcctgacggtctggcgcaggcgttcgtcattggcgccaaccacatcggcgccgat
tcggtggcattggtgttgggggacaacatcttctacggcccaggtctggggaccagcctg
aagcgcttccaatccatcagtggtggagcaattttcgcctattgggtagccaacccgtcg
gcctatggtgtcgttgagttcggcgccgagggcatggcgctgtctctggaggagaagccg
gtgaccccgaagtcgaattacgcggtgccgggcctgtatttctatgacaacgatgtgatc
gaaatcgccaggggtttaaagaaatcagcgcgcggggagtacgagatcaccgaggtcaac
caggtctacctcaatcagggtaggttggcggtcgaggtgctggcccgcgggacagcgtgg
ctggacaccgggacattcgactcgctgctggacgccgccgatttcgtccggaccctggag
cgtcggcagggcctgaaggtcagcatccccgaagaagtggcgtggcgcatgggctggatc
gacgacgagcagctggtgcagcgagcccgtgctctggtcaagtccggatatggtaactac
ctgctggagttgttggagcgcaactga
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