Mycobacterium tuberculosis H37Rv: Rv0780
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Entry
Rv0780 CDS
T00015
Symbol
purC
Name
(RefSeq) phosphoribosylaminoimidazole-succinocarboxamide synthase
KO
K01923
phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:
6.3.2.6
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00230
Purine metabolism
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
Module
mtu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Rv0780 (purC)
Enzymes [BR:
mtu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
Rv0780 (purC)
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Gene cluster
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Motif
Pfam:
SAICAR_synt
Motif
Other DBs
NCBI-GeneID:
888928
NCBI-ProteinID:
NP_215294
TubercuList:
Rv0780
UniProt:
P9WHN1
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Position
873343..874236
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AA seq
297 aa
AA seq
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MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFF
FGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKV
CGIALPPGLVEASRFATPLFTPATKAALGDHDENISFDRVVEMVGALRANQLRDRTLQTY
VQAADHALTRGIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDK
QFVRSWLTGSESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA
NT seq
894 nt
NT seq
+upstream
nt +downstream
nt
atgcgccccgcattgtccgactaccagcatgtggccagcggtaaggtccgcgagatctac
cgtgtcgatgacgagcacctgctgctggttgccagcgaccggatctcggcgtacgactac
gtcctggacagcaccatcccggacaagggccgcgtcctgaccgccatgagcgcattcttc
ttcgggctcgtcgatgcccctaaccatctggccgggccgccggacgacccgcgtatcccc
gacgaggtgctgggccgcgcgctggtggtgcgtcggctggagatgctgccggtggaatgt
gtggcccgtggctacctgaccggttcggggttactggattaccaggcaaccgggaaggta
tgcggtatcgcgctgccgccgggcctggtcgaggccagtcggttcgccacaccgctgttc
accccggcgactaaagccgcgttgggggaccacgacgagaacatctcgtttgaccgggtg
gtggagatggtaggcgcgttgcgtgccaaccagctgcgtgatcgtactctgcagacgtat
gtgcaggccgccgatcacgctctcacccgcggaatcattatcgccgacaccaagtttgaa
tttggcatcgaccgccacggcaacctgctgctggccgacgaaatcttcacaccggactcg
tcgcggtactggcctgccgacgactaccgggccggcgtggtccagaccagcttcgacaaa
cagtttgtccgcagctggctcaccggctccgagtccggctgggatagaggcagcgatcgg
ccgccgcctccgctccccgagcatatcgtcgaggccacgcgtgcccgttatattaatgca
tacgaacggatttccgaactaaaattcgacgactggatcggccctggcgcatga
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