Mycobacterium tuberculosis H37Rv: Rv1475c
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Entry
Rv1475c CDS
T00015
Symbol
acn
Name
(RefSeq) iron-regulated aconitate hydratase
KO
K27802
aconitate hydratase A / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00020
Citrate cycle (TCA cycle)
mtu00630
Glyoxylate and dicarboxylate metabolism
mtu00640
Propanoate metabolism
mtu00720
Other carbon fixation pathways
mtu01100
Metabolic pathways
mtu01120
Microbial metabolism in diverse environments
mtu01200
Carbon metabolism
mtu01210
2-Oxocarboxylic acid metabolism
mtu01230
Biosynthesis of amino acids
Module
mtu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mtu_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
mtu_M00012
Glyoxylate cycle
mtu_M00982
Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Rv1475c (acn)
00630 Glyoxylate and dicarboxylate metabolism
Rv1475c (acn)
00640 Propanoate metabolism
Rv1475c (acn)
09102 Energy metabolism
00720 Other carbon fixation pathways
Rv1475c (acn)
Enzymes [BR:
mtu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
Rv1475c (acn)
4.2.1.99 2-methylisocitrate dehydratase
Rv1475c (acn)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
Aconitase_C
Motif
Other DBs
NCBI-GeneID:
886545
NCBI-ProteinID:
NP_215991
TubercuList:
Rv1475c
UniProt:
O53166
LinkDB
All DBs
Position
complement(1663215..1666046)
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AA seq
943 aa
AA seq
DB search
MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDH
IEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAP
ADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQ
VNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLI
PRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNM
SPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELN
LSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPA
SDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCT
NTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYL
VGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVI
AYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFK
GDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTD
HISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVS
GGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAV
IAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQ
ATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
NT seq
2832 nt
NT seq
+upstream
nt +downstream
nt
gtgactagcaaatctgtgaactcattcggagcccacgacaccctgaaggtcggcgaaaag
agttaccagatctatcgtctcgacgccgtccccaataccgcgaaactcccctacagcctc
aaagtgctcgccgagaacctgttgcgcaacgaggacggcagcaacatcaccaaggaccac
atcgaggccatcgccaactgggaccctaaggccgagcccagcatcgagatccagtacacg
cccgcccgggtggtgatgcaggacttcaccggcgtaccgtgcatcgtcgacttggccacc
atgcgcgaggcgatcgccgatctgggcggcaacccggacaaggtcaacccgctggcgccc
gcagacttggtgatcgaccactcggtgatcgccgatttgttcggccgcgccgacgcattc
gagcgcaacgtcgaaatcgaataccagcgcaacggtgagcgttaccaattcctgcgctgg
ggccaaggcgctttcgacgacttcaaagtggtgccgccgggcaccggcatcgtgcaccag
gtcaatatcgagtacctggccagcgtggtgatgactcgcgacggagtggcctaccccgac
acctgcgtgggcaccgactcacacaccaccatggtcaacggcctgggtgtgctcgggtgg
ggtgtcggcggcatcgaggcggaggccgcgatgctgggtcagccggtatcgatgctgatc
ccgcgggtcgtgggtttcaggttgaccggcgagatccagccgggagtcaccgccaccgac
gtggtgttgaccgtcaccgagatgctgcgccagcacggcgtcgtcggcaaattcgtcgag
ttctacggcgagggcgtggccgaggtgccgctggccaaccgcgccaccctgggcaacatg
agtcccgaattcggttccaccgcagcgattttcccgatcgacgaagaaaccatcaagtat
ctgcggtttaccggtcgcacgccggagcaggtcgcactggtcgaggcctacgccaaggcg
cagggcatgtggcacgatcccaagcacgagccggagttctcggaatacctcgaactcaac
ctatccgacgtggtgccgtcgatcgccggaccaaagcgtccacaggaccgaatcgcgttg
gcgcaagccaaatcaacattccgcgagcagatttaccactatgtcggcaatggttccccg
gattccccccacgacccgcactcgaagctggacgaggtagtcgaggagacattcccggcc
agcgacccggggcagctgacgttcgccaacgacgacgtcgccactgacgaaaccgtgcac
tcggctgccgcgcatgccgatggccgggtgagcaacccagtgcgggtgaagtcggacgaa
ctcggcgaattcgtgctcgaccacggcgcggtggtgattgccgcgatcacgtcctgcacc
aacacctccaaccccgaagtaatgctgggcgcggcgctgctggcccgcaacgccgtcgaa
aagggactgacctcgaagccgtgggtgaagaccacgattgccccgggctcgcaagtggtc
aacgactactacgacagatccggcctgtggccgtatctggagaagctcggcttctatctg
gtcggctacggctgcaccacctgcatcggcaactccgggccgctgcccgaggaaatctca
aaagcggttaacgacaacgacctttcggtgaccgcggtactgtccggcaaccggaacttc
gagggccgtatcaacccagacgtgaagatgaactacctggcatcgccgccgctggtcatc
gcctacgcgctggccgggaccatggacttcgacttccaaacccagccgctcggtcaagac
aaagacggtaagaacgtttttctccgcgatatctggccatcgcagcaggatgtctccgac
accatcgccgcggcgatcaaccaggagatgttcacccgcaactacgccgacgtgttcaag
ggcgacgaccgctggcgcaacctgccaaccccgagcggcaacacctttgagtgggacccg
aattcgacctacgtgcgcaagccgccgtatttcgaggggatgacagccaaacccgaaccg
gtcggcaacatcagcggtgcccgggtgctggcgctgctcggtgattcggtgaccaccgac
cacatctcccccgccggcgccatcaagcccggaactcccgcggcgcgctacctcgacgaa
cacggtgtcgaccgcaaggactacaactccttcggttctcgccgcggcaaccacgaggtg
atgattcgtggcaccttcgccaacatccggctgcgtaaccaactgctagacgacgtgtcc
ggcggttatacccgcgacttcacccagccgggcggtccgcaggcgttcatctacgacgcc
gcgcagaactatgcggcgcaacacattccgctggttgtgttcggcggcaaagagtacggg
tcgggttcgtcacgggactgggcggccaaaggcacattgctactgggcgtgcgggcggtg
atcgccgagtcattcgagcggatccaccggtccaacctgatcggcatgggcgtgatcccg
ctgcagttccccgaaggaaagtcagcgtcgtcgttgggactcgacggtaccgaggtcttc
gacatcaccggtatcgacgtgcttaacgacggcaagacacccaagacggtgtgcgtccag
gccaccaagggcgacggcgccacgatcgagttcgacgccgtggtgcgcatcgacaccccc
ggtgaggcggactactaccgcaacggcggcatcctgcagtacgtgctgcgcaacatactg
aagtcaggctga
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