Mycobacterium tuberculosis H37Rv: Rv1493
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Entry
Rv1493 CDS
T00015
Symbol
mutB
Name
(RefSeq) methylmalonyl-CoA mutase large subunit
KO
K01847
methylmalonyl-CoA mutase [EC:
5.4.99.2
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00280
Valine, leucine and isoleucine degradation
mtu00630
Glyoxylate and dicarboxylate metabolism
mtu00640
Propanoate metabolism
mtu00720
Other carbon fixation pathways
mtu01100
Metabolic pathways
mtu01120
Microbial metabolism in diverse environments
mtu01200
Carbon metabolism
mtu04980
Cobalamin transport and metabolism
Module
mtu_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
Rv1493 (mutB)
00640 Propanoate metabolism
Rv1493 (mutB)
09102 Energy metabolism
00720 Other carbon fixation pathways
Rv1493 (mutB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Rv1493 (mutB)
09150 Organismal Systems
09154 Digestive system
04980 Cobalamin transport and metabolism
Rv1493 (mutB)
Enzymes [BR:
mtu01000
]
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.2 methylmalonyl-CoA mutase
Rv1493 (mutB)
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SSDB
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Paralog
Gene cluster
GFIT
Motif
Pfam:
MM_CoA_mutase
B12-binding
RPAP1_C
Ca_hom_mod
Motif
Other DBs
NCBI-GeneID:
886509
NCBI-ProteinID:
NP_216009
TubercuList:
Rv1493
UniProt:
P9WJK5
Structure
PDB
PDBj
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All DBs
Position
1684005..1686257
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AA seq
750 aa
AA seq
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MTTKTPVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTP
VYIAADRAAAEAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRR
NLAAGQKGLSVAFDLATHRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVS
MTMNGAVLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRIISDI
FAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAGLNAGLDIDSFAPRL
SFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGWSLTAQDVFNN
VARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWG
GSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPV
VGVNKYQVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAEQGR
AGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIA
AATELVEKFAEADGRRPRILIAKMGQDGHDRGQKVIATAFADIGFDVDVGSLFSTPEEVA
RQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGA
TAIFPPGTVIADAAIDLLHRLAERLGYTLD
NT seq
2253 nt
NT seq
+upstream
nt +downstream
nt
atgacaaccaagacacccgtgatcggcagcttcgccggcgttccgctgcatagcgagcgt
gccgcgcaatcgcccacagaggccgcggtgcacacgcatgtcgccgccgccgcggcggcg
cacgggtacacgcccgaacagttggtgtggcacacgccggaaggcattgacgtcacaccg
gtatacatcgccgccgaccgggccgccgccgaagccgagggctacccgctgcacagcttc
ccgggcgagcccccctttgtgcgcggcccctatccgacgatgtatgtgaaccagccgtgg
accatccgccagtacgccgggttttccaccgccgcggattccaatgcgttttaccgacgc
aacctggccgccggccagaaggggctgtcggtggccttcgatctggccacccaccgcggc
tacgactccgaccatccccgcgtgcagggcgatgtcggaatggccggtgtggcaatcgat
tccattctcgacatgcgacagctgttcgacggcatcgacctgtcgaccgtgagcgtgtcg
atgacgatgaacggtgcggtgctgccgatcctggcgctgtatgtggttgccgccgaggag
cagggcgtggcgccggagcagctggccggcaccatccagaacgacatcctcaaagagttc
atggtccgcaacacctacatctatccgccgaagccgtcgatgcggatcatctccgacatc
ttcgcctacaccagcgccaagatgcccaagttcaactccatctccatttccggctatcac
atccaagaagccggtgccacggcggatttggagctggcctacaccctggccgacggcgtc
gactacatcagggcgggcctgaacgccggcctggacatcgacagcttcgcgccccggcta
tcgttcttctggggcatcgggatgaatttctttatggaggtcgccaaactgcgggccggc
cggttgctgtggagtgagctggtcgcacagttcgcgcccaagagcgccaaatccctttcg
ctgcgtacacattcgcaaacatcggggtggtcactgaccgcccaggatgtgttcaacaac
gtggcgcgcacatgcatcgaggcgatggccgccacccaggggcacacccagtcgctgcac
accaacgccctggacgaggcgctggcgctgcccaccgatttttcggcccgcatcgcgcgc
aacacccagctggtgttgcagcaggagtcgggcaccacgcggccgatcgacccgtggggg
ggctcctactatgtggagtggctgacccatcggctcgcgcggcgagcccgggcgcacatc
gccgaggtcgctgaacatggcggcatggcgcaggccatcagcgacggcatccccaagctg
cgcatcgaggaggcggccgcgcgcacccaggcccgcatcgactccggtcagcaaccggtg
gtcggggtgaacaaataccaggtgcccgaggaccacgagatcgaggtgctcaaggtcgaa
aacagccgggtgcgcgccgagcagctggccaaactgcagcggctgcgggcaggccgggac
gagccggcggtacgggccgcgctggccgagctgacccgcgccgccgccgagcaaggacgc
gccggagcagacgggctgggcaataatctgctggccctggccatcgacgccgcccgggcc
caggccaccgtgggcgagatctccgaagcgctggagaaggtgtacggacggcaccgggcc
gagatccgtaccatttccggggtctaccgcgacgaagttggaaaggcccccaacatcgca
gccgcaaccgagctagtggagaagttcgccgaggccgacggccgccggcccaggattctg
atcgccaagatgggccaggacggccacgaccgcgggcagaaggtgatcgcgaccgcgttc
gccgacatcgggttcgacgtcgacgtggggtcgctgttttccacccccgaggaggtggcg
cgtcaggccgccgacaacgacgtgcacgtgatcggggtgtcctcgctggccgccggccat
ctgacgctggtgccggcgctgcgcgacgcgttggcgcaggtgggcaggcccgacatcatg
atcgtggtcggtggtgtcatcccgccgggcgacttcgacgagctgtacgccgccggggcc
accgccattttcccgccggggacggtgattgccgacgcggcgattgacctgctgcacagg
ctggccgagcggctggggtacacgctggattag
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