KEGG   Mycobacterium tuberculosis H37Rv: Rv1638
Entry
Rv1638            CDS       T00015                                 
Symbol
uvrA
Name
(RefSeq) excinuclease ABC subunit UvrA
  KO
K03701  excinuclease ABC subunit A
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    Rv1638 (uvrA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mtu03400]
    Rv1638 (uvrA)
DNA repair and recombination proteins [BR:mtu03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Rv1638 (uvrA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     Supressor
      Rv1638 (uvrA)
SSDB
Motif
Pfam: UvrA_inter UvrA_DNA-bind ABC_tran AAA_29 AAA_21 AAA_16 RsgA_GTPase AAA_25 ScfRs DnaJ_CXXCXGXG NACHT Viral_helicase1 DUF1421
Other DBs
NCBI-GeneID: 885685
NCBI-ProteinID: NP_216154
TubercuList: Rv1638
UniProt: P9WQK7
Structure
LinkDB
Position
1843741..1846659
AA seq 972 aa
MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSA
YARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPH
CPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRV
DGVVHPLTDPPKLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVDH
ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELVV
PDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAKARKAILEGADE
QVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRL
KPEILAVTLAGESKGEHGAKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSR
LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRR
LIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKDS
ITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVLTSVTGVSGSGK
STLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLVRVDQSPIGRTPRSNPATYTGV
FDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCEVCQ
GARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPA
PTLSGGEAQRVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIV
IEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVGGGASAA
TSRSNRRRNVSA
NT seq 2919 nt   +upstreamnt  +downstreamnt
gtggctgaccgcctgatcgtcaagggtgcgcgcgaacacaatctgcgcagcgtcgacctc
gacctgccccgcgacgcgctgatcgtcttcaccgggttatccggatcgggcaagtcctcg
ctcgcgttcgacaccatcttcgccgaggggcagcggcgttacgtggagtcgctgtcggcc
tacgcccgccaatttctcgggcagatggacaagccggacgtcgacttcatcgaggggctg
tctccggcggtgtccatcgaccagaagtcgaccaaccgcaacccacgatcgacggtcggg
accatcaccgaggtgtacgactacctgcggctgttgtatgcgcgcgcgggcacgccgcac
tgcccgacctgcggggagcgagtcgcgcgccaaaccccgcaacaaatcgtcgatcaggtg
ctggccatgccggagggcactcggtttctggtgctggccccggtggtgcgtacccgcaag
ggcgagttcgccgatctgttcgataagctcaacgcccagggctacagccgggtgcgggtc
gacggtgtggtgcatccgctgaccgatccgccgaagctgaaaaagcaggaaaagcacgac
atcgaggtggtggtggaccgtctcaccgtcaaggccgccgccaagcggcggctcaccgat
tcggtggaaaccgcgctgaatttggccgacgggatcgtggtgctcgaattcgtcgatcat
gaactgggtgcaccgcatcgcgagcagcggttctccgagaagctggcctgccccaacggg
cacgcgctggccgtcgacgacctggagccgcggtcgttctcgttcaactcgccctacggc
gcctgccccgaatgcagtggtctgggcatccgcaaggaggtcgacccggagctggtggtg
cccgatccggatcgcaccctggcgcagggtgcggtggcgccgtggtcgaacggccacacc
gcggagtacttcacccggatgatggccggccttggcgaggcgctcgggttcgacgtcgac
acgccctggcgcaagctgccggccaaggcccgcaaggcgattctggaaggcgccgacgag
caggtgcacgtgcgctaccgcaaccgctacggacgcacccggtcgtattacgccgatttc
gagggtgtgctggcgttcctgcaacgcaagatgtcccaaaccgagtccgagcagatgaag
gagcgctacgagggtttcatgcgggacgtgccctgcccggtgtgtgcgggcacccggctc
aagcccgagattctggcggtgacgctggctggggagtccaagggggagcacggcgccaag
tccatcgccgaggtgtgtgagctgtcgatcgccgactgcgcggacttcctgaacgcgctc
acgctgggtccgcgcgagcaagcgatcgccgggcaggtgctcaaggagatccggtcgcgg
ctcgggtttctgctcgacgtcgggctggagtacctgtcgctgtcccgggcggcggccacg
ctgtccggcggtgaggcacaacgtatccggctggccacccagatcggctccggcctggtg
ggtgtgctctacgtgctcgacgagccgtccatcgggctgcaccagcgcgacaaccgtcgt
cttatcgaaaccctcacccggttacgggatttggggaacactttgatcgtcgtcgagcac
gacgaggacaccatcgagcatgcggactggatcgtcgacatcggcccgggggccggtgag
cacggtggccgcatcgtgcacagcgggccctacgatgaactgctacgcaacaaggattcg
atcaccggcgcctacctgtccggccgggaaagcattgagataccggcgattcggcgttcc
gtcgacccccgtcgtcaactcaccgtcgtcggcgcccgcgagcacaacttgcgcgggatc
gatgtgtctttcccgctgggtgtgctgacctcggtgaccggtgtctcgggttcgggcaag
tcgacgttggtcaacgacatcctggccgcggtgctggccaaccgcctcaacggcgcccgg
caggtccccggccggcacacccgggtcaccgggctggactatctggacaagctggtgcgg
gtggaccaatcgccgatcgggcgcacaccgcgatccaacccggccacctacaccggtgtg
ttcgacaagatccgcaccctgttcgccgccaccaccgaggccaaggtccgcggctatcaa
cccggacgattctcgttcaacgtcaagggcggtcgctgcgaggcctgcaccggcgacggc
accatcaagatcgagatgaacttcctgcccgacgtgtacgtgccgtgcgaggtctgccag
ggggcccggtacaaccgcgaaaccctcgaggtgcactacaagggcaagaccgtctcggaa
gtgctggacatgtccatcgaggaagcggcggagttcttcgagccgatcgccggcgtccat
cgctatctacgcaccctggtcgacgtgggcctgggctacgtgcggctcggccagcccgcg
cccacgctgtccggcggtgaggcccagcgggtcaagctggcctcggagctgcagaagcgc
tccaccgggcgcaccgtctacatcctcgacgagccgacgacgggactgcacttcgacgac
atacgcaagctgctcaacgtgatcaacggcctggtcgacaagggcaatacggtgatcgtc
atcgaacataacctggacgtgatcaagacatcggattggatcatcgacctgggcccggag
ggcggtgccggcggcggaaccgttgtcgcccaaggcactccggaggacgttgccgcggtg
ccggcgagctacaccgggaagtttctcgctgaggtcgtcggcggcggtgcctcggccgcc
acatcgcggtcgaacagacggcgcaacgtcagcgcctga

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