Mycobacterium tuberculosis H37Rv: Rv2218
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Entry
Rv2218 CDS
T00015
Symbol
lipA
Name
(RefSeq) lipoyl synthase
KO
K03644
lipoyl synthase [EC:
2.8.1.8
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00785
Lipoic acid metabolism
mtu01100
Metabolic pathways
mtu01240
Biosynthesis of cofactors
Module
mtu_M00881
Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Rv2218 (lipA)
Enzymes [BR:
mtu01000
]
2. Transferases
2.8 Transferring sulfur-containing groups
2.8.1 Sulfurtransferases
2.8.1.8 lipoyl synthase
Rv2218 (lipA)
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Motif
Pfam:
Radical_SAM
LIAS_N
Motif
Other DBs
NCBI-GeneID:
887922
NCBI-ProteinID:
NP_216734
TubercuList:
Rv2218
UniProt:
P9WK91
Structure
PDB
PDBj
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Position
2485273..2486208
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AA seq
311 aa
AA seq
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MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC
PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV
TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN
VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG
CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE
QARNSRALASR
NT seq
936 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtcgctgccgagggccggcgcctgttacgcctggaggtgcgcaacgcgcagacc
ccaatcgagcgcaaaccgccgtggatcaagacacgagcccgcatcgggccggagtacacc
gagctgaagaacctggtccgccgcgaggggctgcacacggtctgcgaggaggccggctgc
cccaacatcttcgaatgctgggaggaccgagaagccaccttcctgatcggcggtgaccag
tgcacccgccgatgcgatttctgccagatcgacaccggaaagcccgccgagctggaccgc
gacgagccacgccgagtcgccgacagcgtgcgcacgatgggcctgcgctatgccaccgtc
accggcgtggctcgcgacgacctgcctgacggcggggcctggctgtacgccgcgaccgtg
cgcgccatcaaggaactcaatccgtcgaccggcgtcgaactgctgattcccgacttcaac
ggcgaaccaacccggctggccgaggtcttcgagtccggcccggaagtcctggcacacaat
gtcgaaaccgtgccccgtatcttcaagcggatccggccggcgttcacgtaccggcgcagc
ctgggtgtgcttaccgctgcgcgcgacgccggcctggtcaccaagagcaacctcatcctc
ggcctgggcgaaacctccgacgaggtgcgcaccgccctgggcgatctgcgcgacgccggc
tgcgacatcgttaccatcacccaatacctgcggccgtcggcgcgccaccatccggtcgag
cgctgggtgaagcccgaggagttcgtccagttcgcgcgattcgccgaagggctgggcttc
gccggggtattggcgggacccctggttaggtcgtcatatcgggcgggccggctctacgaa
caggcacgtaactcacgggccttggcatcccgctag
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