Mycobacterium tuberculosis H37Rv: Rv2496c
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Entry
Rv2496c CDS
T00015
Symbol
bkdB
Name
(RefSeq) 3-methyl-2-oxobutanoate dehydrogenase subunit beta
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00280
Valine, leucine and isoleucine degradation
mtu00640
Propanoate metabolism
mtu00785
Lipoic acid metabolism
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
mtu01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Rv2496c (bkdB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Rv2496c (bkdB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Rv2496c (bkdB)
Enzymes [BR:
mtu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Rv2496c (bkdB)
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Gene cluster
GFIT
Motif
Pfam:
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-GeneID:
888571
NCBI-ProteinID:
NP_217012
TubercuList:
Rv2496c
UniProt:
P9WIS1
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All DBs
Position
complement(2809936..2810982)
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AA seq
348 aa
AA seq
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MTQIADRPARPDETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVAVEGGVF
RVTEGLADTFGADRCFDTPLAESAIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHL
AKYRTRTRGEVDMPVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLL
RHAIACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGNLVSTALS
SADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGAGLAARIQ
EEMFYQLEAPVLRACGFDTPYPPARLEKLWLPGPDRLLDCVERVLRQP
NT seq
1047 nt
NT seq
+upstream
nt +downstream
nt
atgactcaaatcgcagaccgtccggccaggccggatgagacgcttgcggtagcggtgagc
gacatcacgcagtcgttgaccatggtccaggcgatcaaccgcgccctgtacgacgcgatg
gccgccgacgagcgggtattggtgtttggcgaggatgtcgcggtcgagggtggggtgttt
cgggtgaccgagggactggccgatacgttcggtgcagaccggtgcttcgacacgccactg
gcggagtccgcgatcatcggaatagccgtcgggttggcactacgtggctttgtgccggtg
ccagaaatccagttcgacggcttttcctatccggctttcgaccaagtggtgagccatctg
gccaagtaccggactcgcacccgcggtgaggtggacatgccggtgaccgtccggatcccc
tcgtttggcggtatcggtgcggccgaacatcattcggactccacggagtcctactgggtg
cacaccgcgggcctcaaggtggtggtgccgtcgacacccggtgacgcttactggctgctg
cggcacgctatcgcctgcccggaccccgtgatgtatctggagcccaaacgccgctaccac
ggccgcgggatggtcgacactagccggccggaaccgccgatcgggcacgcgatggtgcgc
cggtccggcaccgatgtgaccgtggtaacgtacggaaacctggtgagcaccgccctgtct
agcgcggatactgcagagcagcaacatgattggagtctggaggttatcgatctgcggtcg
ttggcgccgctggacttcgacaccattgctgcgtcgatccagcgcaccgggcgttgcgtg
gtgatgcacgaagggccgcgcagcctcggctatggtgccggtctggccgcgcgcatccag
gaagagatgttctaccaattggaggctccggtgttgcgtgcctgcggttttgacacaccc
tacccgcctgcgcggttggaaaaattgtggttacccggccccgaccggctgttggactgc
gtcgaacgtgtgctgcgtcagccatga
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