KEGG   Mycobacterium tuberculosis H37Rv: Rv2583c
Entry
Rv2583c           CDS       T00015                                 
Symbol
relA
Name
(RefSeq) bifunctional (p)ppGpp synthase/hydrolase RelA
  KO
K01139  GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00230  Purine metabolism
mtu01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    Rv2583c (relA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:mtu03009]
    Rv2583c (relA)
Enzymes [BR:mtu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.6  Diphosphotransferases
    2.7.6.5  GTP diphosphokinase
     Rv2583c (relA)
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.7  Diphosphoric-monoester hydrolases
    3.1.7.2  guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
     Rv2583c (relA)
Ribosome biogenesis [BR:mtu03009]
 Prokaryotic type
  Other maturation factors
   Rv2583c (relA)
SSDB
Motif
Pfam: HD_4 RelA_SpoT TGS ACT_4 HD ACT RelA_AH_RIS ACT_AHAS_ss
Other DBs
NCBI-GeneID: 887888
NCBI-ProteinID: NP_217099
TubercuList: Rv2583c
UniProt: P9WHG9
Structure
LinkDB
Position
complement(2907826..2910198)
AA seq 790 aa
MAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC
TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL
DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV
YDVYRVTSAA
NT seq 2373 nt   +upstreamnt  +downstreamnt
gtggccgaggaccagctcacggcgcaagcggttgcaccgcccacggaggcttctgcggct
ctcgagcccgctctcgagacgcccgagtcgccggtcgagactcttaagaccagcatcagc
gcgtcgcgtcgggtgcgggcccgattggcccggcggatgaccgcccagcgcagcaccacc
aatccggtgctcgagccgttggtggcggtgcaccgggagatctatcccaaggccgacctg
tcgatcttgcagcgagcctacgaggtcgctgaccaaaggcatgccagccagttgcggcag
tccggtgatccctacatcacccacccgttggccgttgccaacattctggccgagttgggc
atggacaccaccactttggtggccgcgctgctgcacgacaccgtcgaggacaccggttac
accctggaggcgttgaccgaggaattcggcgaagaggtgggccatctcgtcgacggggtg
accaagctggatcgggtggtgttgggcagcgccgccgaaggcgagactattcgcaagatg
atcaccgcgatggcccgcgatccgcgggtgctggtgataaaggtggctgaccggttacac
aacatgcgcaccatgcgcttcttgccgccggagaagcaggcccgcaaggcccgtgagacg
ttggaagtcattgcacccctggcgcatcggctgggcatggccagcgtcaagtgggagttg
gaggacctgtccttcgcgatcctgcatcccaagaagtacgaggagatcgtccggctggtc
gccggtcgcgcgccgtcccgggacacctacctggccaaggtgcgtgccgaaatcgtcaac
acgctgaccgcgtcgaagatcaaggcgacggtggagggccgccccaagcactattggtcg
atctaccagaagatgatcgttaagggccgcgacttcgacgacatccacgacctggtcggt
gtgcgcatcctgtgcgacgaaatccgggactgctacgcggctgtcggcgtagtgcattcg
ctatggcagccgatggcgggtcggttcaaggactacatcgcccagcccagatacggtgtg
taccagtcactgcacaccactgtggtcgggcctgagggcaagccgctggaagtgcagatc
cgtacccgcgacatgcaccgcaccgccgaatacggcatcgccgcgcattggcgctacaaa
gaagccaagggccgcaacggtgttcttcatccgcatgccgccgcggagatcgacgacatg
gcctggatgcgtcagctgctcgactggcaacgtgaggcggccgaccccggtgagttcttg
gaatcattgcgctacgaccttgcggtgcaagagattttcgtgtttacccccaagggcgac
gtgatcacgctgccaaccggttcgacgccggtggacttcgcttacgcggtgcacacagag
gtgggccaccgctgcatcggcgcccgagtgaacggccggttggtagcgctggaacgcaag
ctggaaaacggagaagttgtcgaggttttcacgtccaaggcgccgaacgccgggccgtcg
cgggactggcagcagttcgtggtgtcgccgcgcgcaaagacgaagatccgccagtggttc
gccaaggagcggcgtgaggaggcgttggagaccggtaaggatgcgatggcccgcgaggtg
cgccgcggtggacttccgttgcagcgcttggtcaatggtgagtccatggcggcggtggcc
cgcgagctgcactacgcggacgtgtcagcactctataccgccatcggtgaggggcacgtg
tcggcgaaacacgtcgtgcagcggttgttggccgagctcggcggtatcgaccaggcggaa
gaggaactcgccgagcggtccacgccggcgaccatgccgcggcgcccacgcagcaccgac
gatgtcggggtctccgtccccggcgccccgggcgtgctgaccaagctggccaagtgctgc
acgccggttccgggcgatgtgattatggggttcgtcacccgtggcggcggggtcagtgtg
caccgcaccgactgcaccaacgccgcatcgctgcagcagcaggccgagcgcatcatcgag
gtgctatgggcgccgtcgccgtcgtcggtgtttctggtggcaatccaggtcgaggcactc
gaccggcaccggctgctgtcggatgtgacgcgcgcactggccgacgagaaggtcaatatc
ctgtccgcgtcggtcaccacttcgggggaccgggtggcgatcagtcgattcaccttcgag
atgggtgaccccaagcacctcgggcacctgctcaacgccgtccgcaacgtcgaaggtgtc
tacgacgtctaccgggtgacctcggccgcgtag

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