Mycobacterium tuberculosis H37Rv: Rv2682c
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Entry
Rv2682c CDS
T00015
Symbol
dxs1
Name
(RefSeq) 1-deoxy-D-xylulose 5-phosphate synthase
KO
K01662
1-deoxy-D-xylulose-5-phosphate synthase [EC:
2.2.1.7
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00730
Thiamine metabolism
mtu00900
Terpenoid backbone biosynthesis
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
Module
mtu_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
Rv2682c (dxs1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
Rv2682c (dxs1)
Enzymes [BR:
mtu01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase
Rv2682c (dxs1)
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Gene cluster
GFIT
Motif
Pfam:
DXP_synthase_N
Transket_pyr
Transketolase_C
TPP_enzyme_C
E1_dh
PFOR_II
Usp
Transketolase_C_1
Motif
Other DBs
NCBI-GeneID:
887461
NCBI-ProteinID:
YP_177898
TubercuList:
Rv2682c
UniProt:
P9WNS3
Structure
PDB
PDBj
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All DBs
Position
complement(2998052..2999968)
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AA seq
638 aa
AA seq
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MLQQIRGPADLQHLSQAQLRELAAEIREFLIHKVAATGGHLGPNLGVVELTLALHRVFDS
PHDPIIFDTGHQAYVHKMLTGRSQDFATLRKKGGLSGYPSRAESEHDWVESSHASAALSY
ADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAASRRPVIIVVNDNGRSYAPT
IGGVADHLATLRLQPAYEQALETGRDLVRAVPLVGGLWFRFLHSVKAGIKDSLSPQLLFT
DLGLKYVGPVDGHDERAVEVALRSARRFGAPVIVHVVTRKGMGYPPAEADQAEQMHSTVP
IDPATGQATKVAGPGWTATFSDALIGYAQKRRDIVAITAAMPGPTGLTAFGQRFPDRLFD
VGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVLDRAGITG
SDGASHNGMWDLSMLGIVPGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDI
SALERRGGVDVLAAPADGLNHDVLLVAIGAFAPMALAVAKRLHNQGIGVTVIDPRWVLPV
SDGVRELAVQHKLLVTLEDNGVNGGAGSAVSAALRRAEIDVPCRDVGLPQEFYEHASRSE
VLADLGLTDQDVARRITGWVAALGTGVCASDAIPEHLD
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgctgcaacagatccgcgggcccgctgatctgcagcacctttcccaggcgcagcttcgg
gagctggccgccgagatccgtgagttcctgatccacaaggttgccgccacgggggggcat
ctggggccgaacctgggagtggtggaactcaccttggcgctgcaccgggtattcgactcg
ccgcacgatccgatcatcttcgacaccggtcaccaggcctacgtccacaagatgttgacc
ggacgcagccaggacttcgcaaccctgcgtaagaagggcgggttgtcggggtatccgtct
cgtgccgagagcgagcacgactgggtggagtcgagccacgccagcgcggcgctgtcgtac
gcggacgggttggccaaggcgttcgagttgaccggacaccgcaaccggcatgtggtcgcg
gtggtcggtgacggtgcgctcaccggcggtatgtgctgggaggcgctgaacaatatcgcc
gcatcccgccggccggtgattatcgtggtcaacgacaatgggcgcagctacgcgcccaca
atcgggggcgtcgccgaccatctggccacgctgcggctgcagccggcctacgagcaggcg
ctggagacgggccgcgacctggtgcgcgcggtgccgcttgtcggcggtctgtggtttcga
ttcctgcacagcgtcaaggccggcatcaaggactcgctgtcgccgcagttgctgttcacc
gacctcgggttgaagtacgtcggcccggtcgacggccatgacgagcgggcggtggaggtc
gcgctgcgcagcgcgcggcgcttcggtgcaccggtgatcgtgcacgtcgtcacccgcaag
ggcatgggctacccgccggccgaggccgaccaggccgagcagatgcattccacggtcccg
atcgatccggccaccggacaagccaccaaggtggccggcccaggctggacggcgaccttc
tctgatgcacttatcggctacgcccagaaacgccgtgacatcgtggccattaccgcggcc
atgccgggccccaccgggctgaccgcgttcgggcagcgcttcccggatcgattgttcgac
gtcgggatcgccgagcaacacgcgatgacgtcggcggccgggttggcgatgggtgggctg
caccccgtggtggcgatctactcgacgttcctgaaccgggcgttcgaccagatcatgatg
gatgtggcgctgcacaagctgccggtcaccatggtgctggaccgtgccgggatcaccggt
agcgacggcgccagccacaacggaatgtgggacttgtcgatgctgggtatcgtgcccggc
atccgggtggcagcgcccagagacgccacccggttgcgtgaagaactcggcgaggcgctc
gacgtcgacgacggcccgacggcgttacggttccccaaaggtgatgtgggagaagatatt
tcggctttggagcggcgtggaggcgtggatgtgctggcggcgcccgccgatggtttgaac
cacgacgtcctgttggtggccatcggcgcgttcgcaccgatggcgttggcggtggccaag
cggctgcacaaccaggggatcggtgtgacggtgatcgacccgcgctgggtgttgccggtg
tctgacggtgtgcgcgaactggcggtgcagcacaagctgctcgtcacgctagaggacaac
ggggtcaacggtggggcggggtcagcggtgtcggccgcgctgcggcgcgcggagatcgac
gtgccctgccgcgatgtcgggttgccgcaggagttctacgagcacgcgtctcgaagcgag
gtgctggccgatctggggcttaccgaccaggacgtggcccggcggatcaccggctgggtc
gccgcgctgggtaccggggtgtgtgcgtccgacgcgattccagaacatctcgactaa
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