Mycobacterium tuberculosis H37Rv: Rv3377c
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Entry
Rv3377c CDS
T00015
Name
(RefSeq) type B diterpene cyclase
KO
K17811
halimadienyl-diphosphate synthase [EC:
5.5.1.16
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09190 Not Included in Pathway or Brite
09191 Unclassified: metabolism
99980 Enzymes with EC numbers
Rv3377c
Enzymes [BR:
mtu01000
]
5. Isomerases
5.5 Intramolecular lyases
5.5.1 Intramolecular lyases (only sub-subclass identified to date)
5.5.1.16 halimadienyl-diphosphate synthase
Rv3377c
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Mago-bind
Motif
Other DBs
NCBI-GeneID:
888073
NCBI-ProteinID:
NP_217894
TubercuList:
Rv3377c
UniProt:
O50406
Structure
PDB
PDBj
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Position
complement(3790848..3792353)
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AA seq
501 aa
AA seq
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METFRTLLAKAALGNGISSTAYDTAWVAKLGQLDDELSDLALNWLCERQLPDGSWGAEFP
FCYEDRLLSTLAAMISLTSNKHRRRRAAQVEKGLLALKNLTSGAFEGPQLDIKDATVGFE
LIAPTLMAEAARLGLAICHEESILGELVGVREQKLRKLGGSKINKHITAAFSVELAGQDG
VGMLDVDNLQETNGSVKYSPSASAYFALHVKPGDKRALAYISSIIQAGDGGAPAFYQAEI
FEIVWSLWNLSRTDIDLSDPEIVRTYLPYLDHVEQHWVRGRGVGWTGNSTLEDCDTTSVA
YDVLSKFGRSPDIGAVLQFEDADWFRTYFHEVGPSISTNVHVLGALKQAGYDKCHPRVRK
VLEFIRSSKEPGRFCWRDKWHRSAYYTTAHLICAASNYDDALCSDAIGWILNTQRPDGSW
GFFDGQATAEETAYCIQALAHWQRHSGTSLSAQISRAGGWLSQHCEPPYAPLWIAKTLYC
SATVVKAAILSALRLVDESNQ
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggagactttcaggactctgctagcgaaagcggcactaggcaacggcatctcgagcaca
gcctatgacaccgcgtgggtcgcgaagctgggccagctcgatgatgagctaagcgacctc
gccctcaactggctttgcgagcgccagcttcctgacggctcatggggagccgagttccct
ttctgctacgaagatcgactgctctccactttggcggccatgatcagcctcacgtcgaat
aagcatcgtcggaggcgcgcagcgcaagttgaaaaaggcttgctagccctgaagaacctt
acctcgggtgctttcgaaggccctcaacttgatataaaagacgcaaccgtcgggtttgag
ttaatcgcacctacgctgatggctgaggcggcgcgacttggccttgccatttgccacgag
gaatccatcctcggcgagcttgtcggagtgcgtgagcagaagttgagaaaactcggcgga
agcaaaatcaataaacatatcaccgcagctttctccgtagaactggccggccaagacggt
gtcggtatgttggatgtcgataacttgcaggagacaaatggatcggtcaagtattcgcca
tcagcgtcagcctacttcgcgttacatgttaaaccaggagacaagcgggccttggcgtac
atctcatcgataattcaagccggcgatggcggtgcgccggccttctatcaagccgagatt
tttgaaattgtttggtctctatggaatctctcgcgtacggatattgatttgtccgatcct
gagatcgttcgtacgtacctaccctatcttgaccatgtcgaacaacattgggtccgtggt
cgaggtgtggggtggacaggaaattccaccttggaagattgtgacaccacaagtgtggcc
tacgatgttttgtcgaagtttggacggtcgccggatatcggagccgtattacaattcgaa
gacgccgattggttccgtacctactttcacgaagtcggcccctcgatatcgacgaacgtc
cacgtgctcggtgcgttgaagcaggcgggctacgacaaatgtcatccacgagtacgaaag
gttctggaattcatccgatcaagcaaggagcctggacggttctgctggcgggataagtgg
caccgatcggcatattatacgactgcgcatctgatatgtgctgccagtaactatgatgat
gccctatgctcagatgcgattgggtggattcttaatacgcagaggcccgatggctcgtgg
ggatttttcgacggccaagcgactgcggaagagacagcatattgcattcaagctctggcg
cattggcagaggcacagcggcacatccttgtcggcgcagatcagtcgcgcgggtgggtgg
ctatcgcaacactgcgaaccgccatacgcgccgttgtggattgccaagacactttactgc
tcggcgacggtagttaaggctgccatcctaagtgcactgcggctggtcgatgagagtaac
caatga
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