Mycobacterium tuberculosis H37Rv: Rv3379c
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Entry
Rv3379c CDS
T00015
Symbol
dxs2
Name
(RefSeq) 1-deoxy-D-xylulose-5-phosphate synthase
KO
K01662
1-deoxy-D-xylulose-5-phosphate synthase [EC:
2.2.1.7
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00730
Thiamine metabolism
mtu00900
Terpenoid backbone biosynthesis
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
Module
mtu_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
Rv3379c (dxs2)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
Rv3379c (dxs2)
Enzymes [BR:
mtu01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase
Rv3379c (dxs2)
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Gene cluster
GFIT
Motif
Pfam:
DXP_synthase_N
Transket_pyr
Transketolase_C
TPP_enzyme_C
E1_dh
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-GeneID:
888080
NCBI-ProteinID:
NP_217896
TubercuList:
Rv3379c
UniProt:
O50408
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All DBs
Position
complement(3793257..3794867)
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AA seq
536 aa
AA seq
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MFDTGHQTYPHKLLTGRGKDFATLRQADGLSGYPNRHESPHDWVENSHASVSLAWVDGIA
KALALQGQCDRRVIAVIGDGALTGGVAWEGLNNLGAATRPVIVVLNDNGRSYDPTAGALA
AHLEELRVGTPRGPNLFENMGFTYIGPVDGHNIPDTCAVLRKAAAAARPVVVHAVTSKGR
GYPPAEADERDHMHACGVVDIATGLASTPSQRSWTDVFEDEIARIADDRSDVVGLTAAMR
LPTGLGALSRRYPHRVFDSGIAEQHLLASAAGLAAAGTHPVVAVYSTFLHRAFDQLLFDI
GLHRLPVTLVLDRAGVTGPDGPSHHGLWDLALLACVPGFQIACPRDAPRLRQQLRTAIAT
AAPTAVRFPKGAPGEPITAEHTIGGLDVLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLS
EEQIGVTVVDPQWVWPISPALTELAGRHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRT
YTLGLPPAYIPHASRDHILSSHGLTGPAIRIRCKSLLNALHEVPGPEDHPDSGDSY
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
gtgttcgacaccgggcaccaaacctatccgcacaagctgctcaccggccgcggtaaagac
ttcgccacgctgcgccaggccgatggtctatcggggtatcccaaccgccatgaatcgcca
catgactgggtcgagaactcccatgcctcggtcagcctcgcctgggtggacggcatcgcc
aaagcattggccctgcaggggcaatgcgaccgacgtgtcatcgcggtgatcggtgatggc
gccctcaccgggggcgtggcatgggagggcctgaacaacctcggtgccgctacccggccc
gtgatcgtcgtgctcaatgacaatggccgctcctacgaccccaccgctggggctcttgcg
gcacacctagaagaacttcgcgtcggcacaccccgagggccgaacctctttgagaacatg
ggatttacctacatcggtccggtcgatgggcacaacatccccgacacgtgcgcggttcta
cgaaaagcggccgcggcagctaggcccgttgttgttcacgcagtgactagtaagggccgg
ggttatcctccagccgaagctgacgagagggaccatatgcacgcctgcggggtggtcgac
attgccaccggcctcgctagcacacccagtcagcggagctggaccgacgtgttcgaggac
gaaatcgcgcgcattgctgacgaccgatccgacgtcgtcgggctgaccgcggcgatgcgt
ctgcccactggtctaggcgcgctgtcgaggcgatacccgcatcgggtgttcgattcgggc
atcgccgaacaacacctgttggccagcgcggccgggctagctgccgcgggaacccatccc
gttgtcgcggtgtactcgacgtttctgcaccgcgcctttgaccaacttctgttcgacatc
gggctgcaccggttacccgtgacgctggtgctggaccgggctggggtaaccgggcccgac
ggacccagccatcacggtttgtgggatctggcgctgctggcctgcgtgcccgggtttcag
atcgcctgtccgcgcgacgcgcctcggctacgacaacagttgcgtaccgcgatcgcgacc
gcggctcccaccgccgtgcgtttccccaaaggggcgccgggcgaaccgatcacggccgaa
cacaccatcggtggcctcgacgtcttgcatacaccaccaccgcattggcgacccgacgtg
ctcttggtcgcagtgggtgccatgagtcgaccatgcatggacgccgcccggtgcctcagc
gaggagcagatcggggtgacagtcgttgatccacaatgggtctggccaatcagcccggca
ctgaccgagctggctggccgccatcggatcaccgtgtgtgtcgaagatgcgattgccgac
gtgggaatcggcgcgcaccttagccaccacatcgggcggacacacccgcggacgcgcacc
tacacactgggactgccaccggcctacattccccacgccagccgcgaccacatcctttcc
agccacggactcaccggccccgcaatccgcataagatgcaaatcactacttaacgcacta
catgaagtccctggacccgaagaccatcctgattccggcgatagttattaa
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