Mycobacterium tuberculosis H37Rv: Rv3509c
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Entry
Rv3509c CDS
T00015
Symbol
ilvX
Name
(RefSeq) acetohydroxyacid synthase large subunit
KO
K01652
acetolactate synthase I/II/III large subunit [EC:
2.2.1.6
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00290
Valine, leucine and isoleucine biosynthesis
mtu00650
Butanoate metabolism
mtu00660
C5-Branched dibasic acid metabolism
mtu00770
Pantothenate and CoA biosynthesis
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
mtu01210
2-Oxocarboxylic acid metabolism
mtu01230
Biosynthesis of amino acids
Module
mtu_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mtu_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
Rv3509c (ilvX)
00660 C5-Branched dibasic acid metabolism
Rv3509c (ilvX)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Rv3509c (ilvX)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Rv3509c (ilvX)
Enzymes [BR:
mtu01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.6 acetolactate synthase
Rv3509c (ilvX)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
TPP_enzyme_C
TPP_enzyme_N
Motif
Other DBs
NCBI-GeneID:
888267
NCBI-ProteinID:
NP_218026
TubercuList:
Rv3509c
UniProt:
O53554
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Position
complement(3936877..3938424)
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AA seq
515 aa
AA seq
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MNGAQALINTLVDGGVDVCFANPGTSEMHFVAALDAVPRMRGMLTLFEGVATGAADGYAR
IAGRPAAVLLHLGPGLGNGLANLHNARRARVPMVVVVGDHATYHKKYDAPLESDIDAVAG
TVSGWVRRTEAAADVGADAEAAIAASRSGSQIATLILPADVCWSDGAHAAAGVPAQAAAA
PVDVGPVAGVLRSGEPAMMLIGGDATRGPGLTAAARIVQATGARWLCETFPTCLERGAGI
PAVERLAYFAEGAAAQLDGVKHLVLAGARSPVSFFAYPGMPSDLVPAGCEVHVLAEPGGA
ADALAALADEVAPGTVAPVAGASRPQLPTGDLTSVSAADVVGALLPERAIVVDESNTCGV
LLPQATAGAPAHDWLTLTGGAIGYGIPAAVGAAVAAPDRPVLCLESDGSAMYTISGLWSQ
ARENLDVTTVIYNNGAYDILRIELQRVGAGSDPGPKALDLLDISRPTMDFVKIAEGMGVP
ARRVTTCEEFADALRAAFAEPGPHLIDVVVPSLVG
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
gtgaacggtgctcaggccctgatcaacaccctggtcgacgggggtgtcgatgtgtgcttc
gccaaccctggcacgtcggaaatgcatttcgtggcggcgctagacgccgtcccgcgcatg
cgtggcatgctgaccctgttcgaaggcgtggctaccggggccgccgacggttatgcccgc
attgctggccggccggcggcggtgctgctgcatctgggccccggactgggcaacggcctg
gccaacctgcacaacgcgcgccgtgcccgggtgccgatggtggtggttgtcggagaccac
gcgacttaccacaagaagtacgacgccccgctggaatccgatatcgatgcggtcgctggc
accgtttcgggatgggtgcgccggacggaggctgccgccgacgtcggggccgacgctgaa
gcggccattgcggccagccggtcaggttcacagatcgcgacgctgattctgcccgcggat
gtgtgttggagcgacggtgcccacgcggccgcgggcgtgccggctcaggcggcggcggcg
ccagtggacgtggggccggtggctggggtgctgcgctcaggggaacccgccatgatgctg
atcggtggggatgccacccgcgggccggggctgaccgcggctgcgcggatcgtgcaggca
accggggcccgttggttatgcgagacgtttccgacgtgcctggaacgtggcgccggtatc
cccgccgtcgaacggctggcctatttcgctgaaggtgccgcggcccagctggacggggtc
aaacatctcgtgctggccggggccaggtcgccggtgtcgtttttcgcctacccgggtatg
cccagtgacctggtgccggccggttgtgaggtgcacgtgcttgccgaacccggtggtgcg
gccgacgcactggccgcgttggccgacgaggtagcgcccgggacggttgccccggtggcg
ggcgcgtcacgtccgcagctgccgacgggtgacctgacgtcggtgtcggcggccgatgtg
gtcggtgcgttgctgccggaacgggcgattgttgtcgacgagtcgaatacttgtggtgtc
ctgctgccgcaggccaccgccggggccccggcccatgactggcttacgctgaccggcggg
gcaatcggttacggcatcccggctgcggtcggtgccgcggtcgccgcgcccgaccgcccg
gtgttgtgcctggaatccgacgggtcggcaatgtacacgatttcaggattgtggagccaa
gcgcgggagaacctcgacgtcaccaccgtcatctacaacaacggcgcctacgacattctg
cggatcgagctgcaacgtgtcggcgcggggtcggatcctggcccgaaggccctggatctc
cttgatatatcgcgtcccacaatggatttcgtcaagatcgccgaaggtatgggtgttcct
gcacgtcgtgtcaccacctgcgaggaattcgccgacgccctgcgcgcggccttcgccgag
cccgggccgcatctgatcgatgtagtggtgccatcgcttgtggggtag
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