Mycobacterium tuberculosis H37Rv: Rv3708c
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Entry
Rv3708c CDS
T00015
Symbol
asd
Name
(RefSeq) aspartate-semialdehyde dehydrogenase
KO
K00133
aspartate-semialdehyde dehydrogenase [EC:
1.2.1.11
]
Organism
mtu
Mycobacterium tuberculosis H37Rv
Pathway
mtu00260
Glycine, serine and threonine metabolism
mtu00261
Monobactam biosynthesis
mtu00270
Cysteine and methionine metabolism
mtu00300
Lysine biosynthesis
mtu01100
Metabolic pathways
mtu01110
Biosynthesis of secondary metabolites
mtu01120
Microbial metabolism in diverse environments
mtu01210
2-Oxocarboxylic acid metabolism
mtu01230
Biosynthesis of amino acids
Module
mtu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
mtu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mtu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mtu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
Rv3708c (asd)
00270 Cysteine and methionine metabolism
Rv3708c (asd)
00300 Lysine biosynthesis
Rv3708c (asd)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
Rv3708c (asd)
Enzymes [BR:
mtu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.11 aspartate-semialdehyde dehydrogenase
Rv3708c (asd)
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Motif
Pfam:
Semialdhyde_dhC
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
885118
NCBI-ProteinID:
NP_218225
TubercuList:
Rv3708c
UniProt:
P9WNX5
Structure
PDB
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Position
complement(4151180..4152217)
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AA seq
345 aa
AA seq
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MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETA
DPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRR
PKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGG
AEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPD
LLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDES
LVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL
NT seq
1038 nt
NT seq
+upstream
nt +downstream
nt
atgggcctgtcaatagggatcgtgggggccaccggtcaggtgggtcaggtcatgcgcacg
ttgctcgacgagcgggatttcccggcgagcgcggtgcggttcttcgcgtcggcccgatcg
cagggccgcaagctggccttccgcggccaggagatcgaagtggaagacgccgagacggcc
gacccgagcgggctggatatcgcgttgttctccgccggctcggccatgtcgaaggtgcag
gcgccccgctttgcggcggccggagtcacggtgatcgacaactcgtcggcgtggcgtaag
gaccccgacgtgccgttggtggtgtccgaggtgaactttgaacgcgacgcgcaccgccgg
cctaagggcatcatcgccaacccgaactgcaccaccatggccgcgatgccggtgctcaag
gtgctgcacgacgaagcccgactggtgcggttggtggtctcgtcgtatcaggcggtgtcc
ggtagcggcctggccggggtggccgagctggccgagcaggcgcgtgcggtcatcggtggg
gccgagcagctggtgtatgacggcggcgcgctcgagttcccgccgccgaacacctacgtc
gccccgatcgcgttcaacgtggtgccgctggccggatccctggtggacgacggctccggc
gagacagacgaggatcaaaagttgcgcttcgagagccgcaagatccttggcatccccgac
ctgttggtcagcggcacctgtgtgcgggttccggtgttcaccggacactctttgtcgatc
aacgccgagttcgcgcagccgctctcgccggagcgggcgcgcgagctgctcgacggtgct
acgggcgtgcagctggtcgacgtgccgacgccgctggccgccgccggtgtcgacgaatct
ctggtcggccggatccggcgcgacccgggggtgcccgacgggcgtggtctggcgctgttc
gtgtcgggggataacctgcgcaagggggcggcgctgaacaccatccagatcgccgagctg
ctgaccgccgacttgtga
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