Micromonospora tulbaghiae: CSH63_02300
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Entry
CSH63_02300 CDS
T05651
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mtua
Micromonospora tulbaghiae
Pathway
mtua00300
Lysine biosynthesis
mtua00550
Peptidoglycan biosynthesis
mtua01100
Metabolic pathways
mtua01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtua00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CSH63_02300
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CSH63_02300
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CSH63_02300
Enzymes [BR:
mtua01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CSH63_02300
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6707
Motif
Other DBs
NCBI-ProteinID:
AYF26315
UniProt:
A0A386WDD6
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Position
474856..476265
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AA seq
469 aa
AA seq
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MIPLTLAEVAAAVDGRLVGADPDARVTGTVEFDSRKVSPGGLFVAFPGERVDGHDYAAGA
ISAGAVAVLGTREVPGVPMVLVGDALDAMGRLARAVVDRLPGLTVIGLTGSSGKTTTKDL
IAQLAVRLGPTVAPPGSFNNELGHPYTALQATPETRYLVMEKGARGVGHVRYLCDVVPPR
ISVVLNVGVAHLGEFGSVETIALAKGELVEALPDDGLAVLNADDPRVDAMASRTGARVVR
YGESERADVRAVDVTLDGRGRPSYTLVTPEGSAPVRLGLTGRHQVSNSLAAAAVGRELGL
PLPDLAAALNELGLVSTRRMDVFERPDGVTVIDDSYNANPASTGVALRALASMRGDGRTV
AVLGYMAELGDFELQGHQQVGRLAAELGVDRLLVVGEPAAPIHEGATAVGNWGGESVLLT
DQAAAVEVLRSELRPGDVVLVKGSRYRTWEVADALRADARAGATEGGAA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
gtgatcccgctgacgctggccgaggtggccgccgccgtcgacggccggctcgtcggcgcc
gacccggacgcccgggtcaccggcaccgtcgagttcgactcccgcaaggtgagcccgggc
gggctgttcgtcgccttccccggcgagcgggtcgacggccacgactacgcggccggtgcg
atctcggccggcgcggtggcggtgctcggcacccgggaggtgccgggcgtgccgatggtg
ctcgtcggcgacgcgctcgacgcgatgggccggctggcccgcgcggtggtggaccggctg
cccgggctgaccgtgatcgggctgaccggctcgtccggcaagaccaccaccaaggacctg
atcgcccagctcgcggtgcggctcggcccgacggtggcgccgcccggctcgttcaacaac
gagctggggcacccgtacaccgcgttgcaggccacgccggagacccgctacctggtgatg
gagaagggcgcccgcggggtcgggcacgtccgctacctgtgcgacgtggtgccgccgcgg
atctccgtggtgctcaacgtgggcgtggcgcacctgggcgagttcggctcggtggagacc
atcgcgctcgccaagggcgaactggtcgaggcgctgcccgacgacgggctggcggtgctc
aacgcagacgacccgcgggtggacgcgatggcgtcgcgtaccggtgcccgggtggtgcgc
tacggcgagtcggagcgcgccgacgtgcgcgccgtggacgtgacgctcgacggccgggga
cggccctcgtacaccctggtgacgccggagggcagcgcgccggtacggctcgggctgacc
ggccggcaccaggtctccaactcgctcgccgccgcggctgtcggccgggaactgggcctg
ccgctgcccgacctggcggcggcgctgaacgagctgggcctggtctcgacccgccggatg
gacgtcttcgagcgtcccgacggggtgaccgtgatcgacgactcgtacaacgccaacccg
gcgtccaccggcgtggcgctgcgggcgctggccagcatgcgtggcgacgggcgtaccgtc
gcggtgctcggctacatggccgagctgggtgacttcgaactccaggggcatcagcaggtc
ggccggctcgcggccgagctgggagtggaccggctgctcgtggtgggcgagccggcggcg
ccgatccacgagggcgcgacagcggtaggtaattggggaggagagtcggtgctgctcacc
gatcaggcggcggccgtcgaggtgctgcggagcgagctgcgtccaggggacgtggtgctg
gtgaagggctcccggtaccggacctgggaggtggccgacgcgttgcgcgcggacgcccgt
gcgggtgcgacggagggcggcgccgcatga
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