Micromonospora tulbaghiae: CSH63_27590
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Entry
CSH63_27590 CDS
T05651
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mtua
Micromonospora tulbaghiae
Pathway
mtua00290
Valine, leucine and isoleucine biosynthesis
mtua00620
Pyruvate metabolism
mtua01100
Metabolic pathways
mtua01110
Biosynthesis of secondary metabolites
mtua01210
2-Oxocarboxylic acid metabolism
mtua01230
Biosynthesis of amino acids
Module
mtua_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mtua00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CSH63_27590 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CSH63_27590 (leuA)
Enzymes [BR:
mtua01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CSH63_27590 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AYF31135
UniProt:
A0A386WRT7
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Position
complement(5913587..5915332)
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AA seq
581 aa
AA seq
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MAQPVTETDPFASQRPSRMPVHRYVPYDREFGVDLPDRAWPTRRVEAAPRWCAVDLRDGN
QALIDPMSPERKRRMFQLLVQMGYKEIEVGFPSASQTDYDFVRQLIEQDLIPEDVTIQVL
TQCREHLIERTFESLRGARRAIVHFYNSTSTLQRRVVFGLDRDGITDIATQGARLCQKYA
EIHTPDTDIHYEYSPESYTGTELEYALEVCSAVIDVIDPTPDRKLIINLPATVEMAMPNV
YADSIEWMHRRLPRRDSLVLSLHPHNDRGTGVAAAELGLLAGADRIEGCLFGNGERTGNV
DLVTLGLNMFSQGIDPMIDFSNIDEIKRAVEYCNQLPVHERHPYAGDLVYTAFSGSHQDA
INKGFAALNADATAAGVPVDDFTWAVPYLPIDPKDLGRTYEAVIRVNSQSGKGGVAYIMK
TEHQLDLPRRLQIEFSGVVQQVTDHDGGEVEPGAMWEIFARNYLVDHQVDPAVKLADYTI
GTVDGKVEIDARVGFGGDTRALTAVGNGPIDAYVNALQSLGVAVRVLDYHEHALSSGGDA
QAAAYVECEVDGRTVWGVGVDANIVTASIKAVTSAVNRTRA
NT seq
1746 nt
NT seq
+upstream
nt +downstream
nt
atggctcaacctgtcaccgagaccgatccgttcgccagccagcgccccagccggatgccg
gtccaccgctacgttccgtacgaccgtgagttcggcgtcgacctgccggaccgcgcctgg
ccgacccgccgcgtcgaggccgcgccccgctggtgcgcagtcgacctccgcgacggcaac
caggccctgatcgacccgatgtcgcccgagcgcaagcgccggatgttccagctcctggtg
cagatgggctacaaggagatcgaggtcggctttccgtcggcgagccagaccgactacgac
ttcgtacggcagctgatcgagcaggacctgattcccgaggacgtcaccatccaggtgctg
acccagtgccgggagcacctgatcgagcggaccttcgagtcgctgcgcggcgcccgccgg
gccatcgtgcacttctacaactccacctcgacgctgcagcgccgggtggtcttcggcctg
gaccgcgacggcatcaccgacatcgccacgcagggcgcgcggctgtgccagaagtacgcg
gagatccacaccccggacaccgacatccactacgagtactcgccggagtcgtacacgggc
accgagctggagtacgcgctggaggtctgctcggcggtcatcgacgtgatcgacccgacg
ccggaccggaagctgatcatcaacctgccggccaccgtcgagatggcgatgccgaacgtc
tacgccgactcgatcgagtggatgcaccggcgcctgccccggcgggacagcctggtgctg
agtctgcacccgcacaacgaccggggcaccggcgtggccgccgccgagctgggcctgctg
gccggcgccgaccggatcgagggctgcctgttcggcaacggcgagcgcaccggcaacgtg
gacctggtgacgctgggcctgaacatgttctcccagggcatcgacccgatgatcgacttc
tcgaacatcgacgagatcaagcgcgccgtcgagtactgcaaccagctcccggtgcacgag
cgccacccgtacgcgggcgacctggtctacaccgcgttctccggctcgcaccaggacgcg
atcaacaagggcttcgccgcgctgaacgccgacgccacggcggccggggtgccggtcgac
gacttcacctgggcggtgccctacctgccgatcgacccgaaggacctgggccgcacctac
gaggcggtcatccgggtcaactcgcagtccggcaagggcggcgtcgcgtacatcatgaag
accgagcaccagctcgacctgccgcgccgcctccagatcgagttctccggcgtggtgcag
caggtcaccgaccacgacggcggcgaggtcgagccgggcgccatgtgggagatcttcgcc
cgcaactacctggtcgaccaccaggtcgacccggccgtcaagctggccgactacaccatc
ggcaccgtcgacggcaaggtcgagatcgacgcccgcgtcggcttcggcggcgacacccgc
gcgctcaccgctgtcggcaacggcccgatcgacgcgtacgtcaacgcgttgcagtccctg
ggcgtggcggtacgggtgctcgactaccacgagcacgcgctgtcctccggcggggacgcg
caggccgccgcgtacgtggagtgcgaggtggacggccgcacggtgtggggcgtcggggtg
gacgccaacatcgtcaccgcctcgatcaaggcggtcacgagcgcggtgaaccgcacccgc
gcctga
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