Mycobacterium tuberculosis EAI5/NITR206: J114_05140
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Entry
J114_05140 CDS
T02653
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mtue
Mycobacterium tuberculosis EAI5/NITR206
Pathway
mtue00230
Purine metabolism
mtue00670
One carbon pool by folate
mtue01100
Metabolic pathways
mtue01110
Biosynthesis of secondary metabolites
Module
mtue_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mtue00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
J114_05140 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
J114_05140 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mtue04147
]
J114_05140 (purH)
Enzymes [BR:
mtue01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
J114_05140 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
J114_05140 (purH)
Exosome [BR:
mtue04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
J114_05140 (purH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Phage_zn_bind_3
DUF7127
Motif
Other DBs
NCBI-ProteinID:
AGL30405
LinkDB
All DBs
Position
1066661..1068232
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AA seq
523 aa
AA seq
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MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL
TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG
ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL
AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT
AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV
LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA
CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE
TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgacgacggaagacggccgatccgccgtgcgctgatcagcgtgtacgacaag
accgggctggtagacctggcacagggcctgagcgcggccggcgtcgagatcatctcgact
gggtcaacggccaagaccattgccgacaccgggattccggtgacccccgtggagcagctg
accggctttcccgaggtgctcgatggccgggtcaagacactgcacccgcgagtgcatgcc
gggctgctggctgacctgcgcaagtccgagcacgccgcggccctcgagcaactcgggatc
gaggctttcgaactcgttgtagtcaacttgtatccgttcagccagaccgtcgaatccggc
gccagtgtcgacgactgcgtcgagcagattgatatcggcgggccggcgatggtgcgggcc
gccgccaaaaaccatcccagcgcggcggtggtcaccgatccgcttgggtaccatggcgtg
cttgccgcactgcgcgccggcggattcaccctcgccgagcgcaaaaggctggcgtcgtta
gcgtttcagcatatagccgagtacgacatcgccgtcgcgagctggatgcaacagacccta
gcgcccgaacatcctgttgccgcctttccgcagtggttcggccgaagctggcgccgcgtg
gcgatgctgcgctacggcgagaacccgcaccaacaggccgctctctacggcgaccccacc
gcctggccggggctggcccaggccgagcaactgcacggaaaagacatgtcctacaacaac
ttcaccgatgcggacgcagcctggcgggccgccttcgaccacgaacaaacgtgcgtggcg
atcatcaagcacgccaacccgtgcggcatcgcaatctcgtccgtttcggtcgccgacgcg
catcgcaaggctcacgaatgcgatccgctgagcgcctacggcggggtcatcgccgccaat
accgaggtcagtgtcgaaatggccgagtatgtgagcaccatcttcaccgaagtcatcgtc
gcgcctggctacgcccccggggccctcgatgtgctggcccgcaagaagaacatccgggtg
ctggtagccgcggagccactggccggtggcagcgagttgcgtccgatcagcggtggactg
ctgatacagcagagcgaccagcttgacgcgcacggtgacaacccggcgaactggaccttg
gcgaccgggtcacctgcggaccccgcgacgctgaccgacctggtcttcgcgtggcgagcc
tgccgtgcggtcaagtcgaacgcgatagtgatagctgccgacggcgccaccgtcggcgtc
gggatgggtcaggtcaaccgtgtcgacgccgcccggttggccgtcgaacgcggcggcgag
cgggttcgcggcgcggtggcagcctcggatgcgttcttcccctttcccgacggcctggaa
acgttggccgccgcgggggtcaccgcggtcgtccaccccggtggctcggtgcgcgacgag
gaagtgaccgaagcggcggccaaggccggtgtcaccctatatctcaccggggcgcggcac
ttcgcgcactga
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