KEGG   Mycobacterium tuberculosis BT2: HKBT2_3675
Entry
HKBT2_3675        CDS       T03153                                 
Symbol
rmlB
Name
(GenBank) dTDP-glucose-4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
mtuu  Mycobacterium tuberculosis BT2
Pathway
mtuu00521  Streptomycin biosynthesis
mtuu00523  Polyketide sugar unit biosynthesis
mtuu00525  Acarbose and validamycin biosynthesis
mtuu00541  Biosynthesis of various nucleotide sugars
mtuu01100  Metabolic pathways
mtuu01110  Biosynthesis of secondary metabolites
mtuu01250  Biosynthesis of nucleotide sugars
Module
mtuu_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:mtuu00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    HKBT2_3675 (rmlB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    HKBT2_3675 (rmlB)
   01055 Biosynthesis of vancomycin group antibiotics
    HKBT2_3675 (rmlB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    HKBT2_3675 (rmlB)
   00525 Acarbose and validamycin biosynthesis
    HKBT2_3675 (rmlB)
Enzymes [BR:mtuu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     HKBT2_3675 (rmlB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD RmlD_sub_bind NAD_binding_4 Polysacc_synt_2 NAD_binding_10 adh_short Sacchrp_dh_NADP VbhA NmrA KR
Other DBs
NCBI-ProteinID: AHJ48472
LinkDB
Position
3872589..3873584
AA seq 331 aa
MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
LRTTIDWYRDNESWWRPLKDATEARYQERGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgcggttgctagtcaccggtggcgcgggattcatcggcacgaatttcgtgcacagcgcc
gtacgtgagcatccagacgatgcggttaccgtactcgacgccctgacctacgccggccgg
cgcgagtcgctggccgacgtggaggatgccatccggctggttcagggcgatatcaccgac
gccgagctggtttcgcagctggtggccgagtccgacgcggtggtgcattttgccgccgaa
tcccatgtcgacaatgcactggacaatccggagccgtttctgcacaccaacgtcatcggg
accttcaccatcctggaagcggtgcgacgccacggtgtgcgcctgcaccacatctccacc
gacgaggtctacggcgacttggagctcgacgaccgggcgcggttcaccgaatcgacgccc
tataacccgtccagcccttactcggcgaccaaggcgggcgcagacatgttggtccgggcc
tgggttcggtcctatggcgtacgcgcgacgatctccaactgctccaacaactacgggccg
tatcagcacgtcgagaagttcattccgcgtcagatcaccaatgtgctcaccgggcggcgg
cccaagctctacggcgcgggcgccaatgtccgtgactggatccacgtcgacgaccacaac
agcgcggtgcggcgaatcctggacagaggccgcatcggccgaacctacctgatcagctcc
gagggcgagcgtgacaacctgaccgtgctgcgcacgctgctgcgactgatggaccgcgat
ccggacgacttcgaccacgtcaccgaccgcgtcggccacgacctgcgctatgccatcgac
ccgtccacgctctacgacgaattatgctgggcgccaaagcataccgatttcgaggagggc
ctgcggaccacgatcgactggtaccgcgacaacgaatcgtggtggcgtccactaaaagac
gccacggaggcccgctatcaagaacgcggtcaatga

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