Mycobacterium tuberculosis H37Rv: RVBD_2225
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Entry
RVBD_2225 CDS
T02178
Name
(GenBank) 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB
KO
K00606
3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:
2.1.2.11
]
Organism
mtv
Mycobacterium tuberculosis H37Rv
Pathway
mtv00770
Pantothenate and CoA biosynthesis
mtv01100
Metabolic pathways
mtv01110
Biosynthesis of secondary metabolites
mtv01240
Biosynthesis of cofactors
Module
mtv_M00119
Pantothenate biosynthesis, valine/L-aspartate => pantothenate
Brite
KEGG Orthology (KO) [BR:
mtv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
RVBD_2225
Enzymes [BR:
mtv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase
RVBD_2225
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GFIT
Motif
Pfam:
Pantoate_transf
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
AFN50175
UniProt:
P9WIL7
Structure
PDB
PDBj
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Position
2497750..2498595
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AA seq
281 aa
AA seq
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MSEQTIYGANTPGGSGPRTKIRTHHLQRWKADGHKWAMLTAYDYSTARIFDEAGIPVLLV
GDSAANVVYGYDTTVPISIDELIPLVRGVVRGAPHALVVADLPFGSYEAGPTAALAAATR
FLKDGGAHAVKLEGGERVAEQIACLTAAGIPVMAHIGFTPQSVNTLGGFRVQGRGDAAEQ
TIADAIAVAEAGAFAVVMEMVPAELATQITGKLTIPTVGIGAGPNCDGQVLVWQDMAGFS
GAKTARFVKRYADVGGELRRAAMQYAQEVAGGVFPADEHSF
NT seq
846 nt
NT seq
+upstream
nt +downstream
nt
atgtctgagcagactatctatggggccaatacccccggaggctccgggccgcggaccaag
atccgcacccaccacctacagagatggaaggccgacggccacaagtgggccatgctgacg
gcctacgactattcgacggcccggatcttcgacgaggccggcatcccggtgctgctggtc
ggtgattcggcggccaacgtcgtgtacggctacgacaccaccgtgccgatctccatcgac
gagctgatcccgctggtccgtggcgtggtgcggggtgccccgcacgcactggtcgtcgcc
gacctgccgttcggcagctacgaggcggggcccaccgccgcgttggccgccgccacccgg
ttcctcaaggacggcggcgcacatgcggtcaagctcgagggcggtgagcgggtggccgag
caaatcgcctgtctgaccgcggcgggcatcccggtgatggcacacatcggcttcaccccg
caaagcgtcaacaccttgggcggcttccgggtgcagggccgcggcgacgccgccgaacaa
accatcgccgacgcgatcgccgtcgccgaagccggagcgtttgccgtcgtgatggagatg
gtgcccgccgagttggccacccagatcaccggcaagcttaccattccgacggtcgggatc
ggcgctgggcccaactgcgacggccaggtcctggtatggcaggacatggccgggttcagc
ggcgccaagaccgcccgcttcgtcaaacggtatgccgatgtcggtggtgaactacgccgt
gctgcaatgcaatacgcccaagaggtggccggcggggtattccccgctgacgaacacagt
ttctga
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