Mycobacterium tuberculosis H37Rv: RVBD_2678c
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Entry
RVBD_2678c CDS
T02178
Name
(GenBank) uroporphyrinogen decarboxylase HemE
KO
K01599
uroporphyrinogen decarboxylase [EC:
4.1.1.37
]
Organism
mtv
Mycobacterium tuberculosis H37Rv
Pathway
mtv00860
Porphyrin metabolism
mtv01100
Metabolic pathways
mtv01110
Biosynthesis of secondary metabolites
mtv01240
Biosynthesis of cofactors
Module
mtv_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mtv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RVBD_2678c
Enzymes [BR:
mtv01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.37 uroporphyrinogen decarboxylase
RVBD_2678c
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Gene cluster
GFIT
Motif
Pfam:
URO-D
DUF6726
Motif
Other DBs
NCBI-ProteinID:
AFN50651
UniProt:
P9WFE1
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All DBs
Position
complement(2993999..2995072)
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AA seq
357 aa
AA seq
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MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE
ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ
AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA
LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP
MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV
VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgagtacccgtcgcgaccttccgcagtcgccgtatctggccgccgtcaccggccgcaag
cccagccgggtgccggtgtggttcatgcggcaggccgggcgctcgttgcccgaataccgg
gcgctgcgcgagcggtacagcatgctggcggcctgtttcgaaccggacgtggcctgtgag
attaccctgcagccgatacgccgctacgacgtcgacgcggccatcctgttctccgacatc
gtggtgccgctacgggcggccggcgtggatttggacatcgtcgccgacgttgggccggtg
atcgcggacccggtgcgcaccgccgccgatgtcgccgccatgaaaccacttgatccacaa
gcgattcaaccggtattggtggcggcttcgttgttggtcgctgagcttggcgacgtgccg
ctgatcggtttcgccggcgcgccgttcacgctggcctcctacctcgtggagggcggaccg
agccgccatcacgcccacgtcaaggcgatgatgttggccgagccggcgagctggcacgcg
ctgatggccaagctgaccgacctcaccatcgcgtttctggtcggccaaatcgacgcgggg
gtggacgccatccaggtattcgactcctgggccggggcgctctcgccgatcgactaccgc
cagtacgtgttgccgcacagcgcccgggtgttcgctgcgctgggcgagcatggcgtgccg
atgacgcacttcggggttgggaccgccgaattgctgggcgcgatgtcggaggccgtgaca
gccggggagcggccaggccgaggggccgtcgtcggcgtggactggcggaccccgctgacc
gacgccgccgcccgggtggtgcccggcacggcgttacagggcaacctcgatccggcggtg
gtcctggcgggctggccggcggtggaacgtgccgcacgtgccgttgtcgacgacggacgc
cgcgccgtcgacgccggtgcggccggccatatcttcaacctcggccacggggtgctgcca
gaaagcgatcccgcggtgctggccgacctggtctcgctcgtacactcgctatga
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