KEGG   Mycobacterium tuberculosis H37Rv: RVBD_3464
Entry
RVBD_3464         CDS       T02178                                 
Name
(GenBank) dTDP-glucose 4,6-dehydratase RmlB
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
mtv  Mycobacterium tuberculosis H37Rv
Pathway
mtv00521  Streptomycin biosynthesis
mtv00523  Polyketide sugar unit biosynthesis
mtv00525  Acarbose and validamycin biosynthesis
mtv00541  Biosynthesis of various nucleotide sugars
mtv01100  Metabolic pathways
mtv01110  Biosynthesis of secondary metabolites
mtv01250  Biosynthesis of nucleotide sugars
Module
mtv_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:mtv00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    RVBD_3464
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    RVBD_3464
   01055 Biosynthesis of vancomycin group antibiotics
    RVBD_3464
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    RVBD_3464
   00525 Acarbose and validamycin biosynthesis
    RVBD_3464
Enzymes [BR:mtv01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     RVBD_3464
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD RmlD_sub_bind NAD_binding_4 Polysacc_synt_2 NAD_binding_10 adh_short Sacchrp_dh_NADP VbhA NmrA KR
Other DBs
NCBI-ProteinID: AFN51482
UniProt: P9WN65
LinkDB
Position
3882016..3883011
AA seq 331 aa
MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
LRTTIDWYRDNESWWRPLKDATEARYQERGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgcggttgctagtcaccggtggcgcgggattcatcggcacgaatttcgtgcacagcgcc
gtacgtgagcatccagacgatgcggttaccgtactcgacgccctgacctacgccggccgg
cgcgagtcgctggccgacgtggaggatgccatccggctggttcagggcgatatcaccgac
gccgagctggtttcgcagctggtggccgagtccgacgcggtggtgcattttgccgccgaa
tcccatgtcgacaatgcactggacaatccggagccgtttctgcacaccaacgtcatcggg
accttcaccatcctggaagcggtgcgacgccacggtgtgcgcctgcaccacatctccacc
gacgaggtctacggcgacttggagctcgacgaccgggcgcggttcaccgaatcgacgccc
tataacccgtccagcccttactcggcgaccaaggcgggcgcagacatgttggtccgggcc
tgggttcggtcctatggcgtacgcgcgacgatctccaactgctccaacaactacgggccg
tatcagcacgtcgagaagttcattccgcgtcagatcaccaatgtgctcaccgggcggcgg
cccaagctctacggcgcgggcgccaatgtccgtgactggatccacgtcgacgaccacaac
agcgcggtgcggcgaatcctggacagaggccgcatcggccgaacctacctgatcagctcc
gagggcgagcgtgacaacctgaccgtgctgcgcacgctgctgcgactgatggaccgcgat
ccggacgacttcgaccacgtcaccgaccgcgtcggccacgacctgcgctatgccatcgac
ccgtccacgctctacgacgaattatgctgggcgccaaagcataccgatttcgaggagggc
ctgcggaccacgatcgactggtaccgcgacaacgaatcgtggtggcgtccactaaaagac
gccacggaggcccgctatcaagaacgcggtcaatga

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