Mycobacterium tuberculosis H37Rv: RVBD_3708c
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Entry
RVBD_3708c CDS
T02178
Name
(GenBank) aspartate-semialdehyde dehydrogenase Asd
KO
K00133
aspartate-semialdehyde dehydrogenase [EC:
1.2.1.11
]
Organism
mtv
Mycobacterium tuberculosis H37Rv
Pathway
mtv00260
Glycine, serine and threonine metabolism
mtv00261
Monobactam biosynthesis
mtv00270
Cysteine and methionine metabolism
mtv00300
Lysine biosynthesis
mtv01100
Metabolic pathways
mtv01110
Biosynthesis of secondary metabolites
mtv01120
Microbial metabolism in diverse environments
mtv01210
2-Oxocarboxylic acid metabolism
mtv01230
Biosynthesis of amino acids
Module
mtv_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
mtv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
mtv_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mtv00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
RVBD_3708c
00270 Cysteine and methionine metabolism
RVBD_3708c
00300 Lysine biosynthesis
RVBD_3708c
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
RVBD_3708c
Enzymes [BR:
mtv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.11 aspartate-semialdehyde dehydrogenase
RVBD_3708c
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Motif
Pfam:
Semialdhyde_dhC
Semialdhyde_dh
Motif
Other DBs
NCBI-ProteinID:
AFN51729
UniProt:
P9WNX5
Structure
PDB
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Position
complement(4151358..4152395)
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AA seq
345 aa
AA seq
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MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETA
DPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRR
PKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGG
AEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPD
LLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDES
LVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL
NT seq
1038 nt
NT seq
+upstream
nt +downstream
nt
atgggcctgtcaatagggatcgtgggggccaccggtcaggtgggtcaggtcatgcgcacg
ttgctcgacgagcgggatttcccggcgagcgcggtgcggttcttcgcgtcggcccgatcg
cagggccgcaagctggccttccgcggccaggagatcgaagtggaagacgccgagacggcc
gacccgagcgggctggatatcgcgttgttctccgccggctcggccatgtcgaaggtgcag
gcgccccgctttgcggcggccggagtcacggtgatcgacaactcgtcggcgtggcgtaag
gaccccgacgtgccgttggtggtgtccgaggtgaactttgaacgcgacgcgcaccgccgg
cctaagggcatcatcgccaacccgaactgcaccaccatggccgcgatgccggtgctcaag
gtgctgcacgacgaagcccgactggtgcggttggtggtctcgtcgtatcaggcggtgtcc
ggtagcggcctggccggggtggccgagctggccgagcaggcgcgtgcggtcatcggtggg
gccgagcagctggtgtatgacggcggcgcgctcgagttcccgccgccgaacacctacgtc
gccccgatcgcgttcaacgtggtgccgctggccggatccctggtggacgacggctccggc
gagacagacgaggatcaaaagttgcgcttcgagagccgcaagatccttggcatccccgac
ctgttggtcagcggcacctgtgtgcgggttccggtgttcaccggacactctttgtcgatc
aacgccgagttcgcgcagccgctctcgccggagcgggcgcgcgagctgctcgacggtgct
acgggcgtgcagctggtcgacgtgccgacgccgctggccgccgccggtgtcgacgaatct
ctggtcggccggatccggcgcgacccgggggtgcccgacgggcgtggtctggcgctgttc
gtgtcgggggataacctgcgcaagggggcggcgctgaacaccatccagatcgccgagctg
ctgaccgccgacttgtga
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