Methylosinus trichosporium: CQW49_11210
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Entry
CQW49_11210 CDS
T05155
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mtw
Methylosinus trichosporium
Pathway
mtw00300
Lysine biosynthesis
mtw00550
Peptidoglycan biosynthesis
mtw01100
Metabolic pathways
mtw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CQW49_11210
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CQW49_11210
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CQW49_11210
Enzymes [BR:
mtw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CQW49_11210
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ATQ68385
UniProt:
A0A2D2D075
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All DBs
Position
2333925..2335349
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AA seq
474 aa
AA seq
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MKAESLWSGLGLVGALRARVSGGLPRDASGISIDTRTLAPGDLFFAIKGEARDGHDFVAA
AFERGAAGAVVDEAHAGALAGRAPLYVVKDVQESLERLGARARERSAAYVVGVTGSVGKT
STKEMAAAVLSRFGAAHASAASYNNQWGVPLSLARMPAATRFGVFEIGMNHAGEIAALAP
LVEPHVALVTRVAPVHLEHFACLEAIADAKSEIFSGVVDGGVAILNRDDETFERMLEAAA
ASRAAHVFGFGVSEGAQARLLSYDPRENSVEADIFGRRLRYRIGAPGRHFALNSLAVLTI
AHVLDLDLAQASAALAEFAPPKGRGRREQLPAGAVPLTLIDESYNANPTSMRAALELLGA
ERPIGRRVAVLGDMLELGPSAAELHAELASDLEAAGVDLLFTAGPLMARLYYAAPERMRG
AHRATARELEEAVLDSLGAGDVVMIKGSNGSRMTRIVEAIRTKFAPASDGATEQ
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcagaatccctatggtcggggctcggattggtcggagcgctgcgcgcgcgcgtc
agcggcggcctgccgcgcgacgcgtccggaatctcgatcgacacgcgcacgctcgcgccg
ggcgacctcttcttcgcgatcaagggcgaagcgcgcgacggccatgacttcgtggccgcc
gccttcgagcgcggcgccgccggcgccgtcgtcgacgaggcccatgcgggagcgctcgcc
gggcgcgcgccgctctatgtcgtcaaggacgtgcaggagtcgctggagcgtctcggcgcg
cgcgcgcgcgagcgctccgccgcttatgtcgtcggcgtcaccggctccgtcggcaagact
tcgacgaaggaaatggccgccgccgtgctgtcgcgcttcggcgccgcgcacgcctccgcc
gcatcctacaataatcaatggggcgtgccgctgtcgctggcgcgcatgccggcggcgacg
cgcttcggcgtgttcgagatcggcatgaatcacgccggcgagatcgctgcgctcgcgccg
ctggtcgagccgcatgtcgcgctggtgacgcgcgtcgcgccggtgcatctcgagcatttc
gcctgcctagaggcgatcgccgacgccaagtcggaaatcttctccggcgtcgtcgacggc
ggcgtcgccatactcaatcgcgacgacgagaccttcgagcgcatgctcgaggccgccgcc
gcctcgcgcgccgcgcatgtgttcggcttcggcgtgtccgaaggcgcgcaggcgcggctg
ctctcctatgatccgcgcgagaacagcgtcgaggccgatattttcgggcgccggctgcgc
tatcgcatcggcgcgccgggacgccatttcgcgctcaactcgctcgccgttctgaccatc
gcccatgtgctcgatctcgatctcgcgcaagcctcggcggcgctcgcggaattcgcgccg
cccaagggtcgcggaaggcgcgagcagctgcccgccggcgccgtgccgctgaccttgatc
gacgagagctacaacgccaatccgacctcgatgcgcgccgcgctcgagctgctcggcgcc
gagcggccgatcggccggcgcgtcgccgtgctcggcgacatgctggagctcggaccgagc
gccgccgaattgcacgccgagctggcgtccgatctggaggcggcgggcgtcgatcttctc
ttcaccgccggaccgctgatggcgcggctctattacgccgcgcccgagcgaatgcgcggc
gcgcatcgcgccacggcgcgcgagctcgaggaggcagtgctcgattcgctcggcgccggc
gacgttgtgatgatcaaaggctcgaacggctcgcgcatgacgcggatcgtcgaagcgata
aggacgaaattcgctcccgcgtcggatggcgcgaccgagcagtag
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