Mycobacterium tuberculosis EAI5: M943_04195
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Entry
M943_04195 CDS
T02749
Name
(GenBank) phosphoribosylglycinamide synthetase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
mtx
Mycobacterium tuberculosis EAI5
Pathway
mtx00230
Purine metabolism
mtx01100
Metabolic pathways
mtx01110
Biosynthesis of secondary metabolites
Module
mtx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mtx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M943_04195
Enzymes [BR:
mtx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
M943_04195
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
FGAR-AT_PurM_N-like
Motif
Other DBs
NCBI-ProteinID:
AGQ34309
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Position
894437..896737
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AA seq
766 aa
AA seq
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MSPLARTPRKTSVLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYS
VMWSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHP
SYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGN
SLGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGI
GGVSVLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSC
ATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKW
EVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAK
LSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGR
GIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQF
TQAVRGLADGCADLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAE
PGETLMLLGDTRDEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAH
DLSEGGLAQAIVESALAGETGCRILLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMC
EARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG
NT seq
2301 nt
NT seq
+upstream
nt +downstream
nt
atgtctccgctcgcccggaccccgcgcaaaacgtcggtgctggacaccgtcgaacacgcc
gcgaccacacccgaccaaccacaaccgtatggtgagctgggcctcaaagacgacgagtac
cggcggattcgccagatcctgggccgccggcccaccgacaccgagctggccatgtactcg
gtgatgtggagcgaacactgttcgtacaagtcctccaaggtgcacctgcgctacttcggt
gagaccacctccgacgagatgcgcgcggccatgctggccggcatcggcgagaacgccggc
gtcgtcgacatcggcgacggctgggcggtcaccttcaaggtggagtcacacaaccacccg
tcctacgtcgagccctaccagggcgcggccaccggggtgggcggcatcgtccgcgacatc
atggccatgggcgcccgaccggtcgccgtgatggaccagcttcggttcggcgccgccgac
gcccccgatacccgccgcgtgctcgacggcgtggtccgcggcatcggcggatacggcaac
tccctgggcctgcccaacattggcggagagaccgtcttcgacccgtgctacgccggcaac
cccttagtgaacgcgttgtgtgtcggcgtattacggcaggaggacctgcatttggcgttc
gcctccggcgccggcaacaagatcatcctgtttggcgcgcgcaccgggctcgacggtatc
ggcggggtgtcggtgctggcgtcggacaccttcgatgccgagggatcccgcaagaagctg
ccctcggtgcaggtcggcgacccgttcatggagaaggtgctcatcgaatgctgtctcgag
ctctacgcgggcggcctggtgatcggcatccaagacctgggcggagccggattatcttgt
gccacatcggagttagcatccgccggtgatggcggaatgacgatccagctggacagcgtc
ccgctgcgggccaaggagatgacgcccgccgaggtgctctgcagcgaatcgcaggagcgg
atgtgcgcggtggtctccccgaagaacgtcgacgcattcctggcggtgtgccgcaagtgg
gaggtgctggcgacggtgatcggcgaggtcaccgacggcgaccggctgcagatcacctgg
cacggcgagacggtggtcgacgtgccgccgcgcaccgtagctcacgaaggtccggtatat
cagcgcccggtcgcccgccccgatacgcaggacgcgctgaacgccgaccgctcggccaag
ctgtcacggccggtcaccggcgacgagctgcgcgcgactttgcttgcgttacttggcagc
ccgcacctgtgcagccgcgcgttcatcaccgagcagtacgaccgctatgtgcgcggcaac
acggtgctcgccgagcacgccgacggcggcatgctgcgcatcgacgagtcgaccggccgg
ggcatcgcggtatcgaccgacgcgtcgggacgctacacgctgctggatccctacgctggc
gcgcaactcgcgttggccgaggcgtaccgcaacgtcgccgtcaccggcgccaccccggtc
gcggtgaccaactgcctgaacttcggttcccccgaggaccccggcgtgatgtggcagttc
acgcaggcggtccgcggtctggccgatggctgtgcggacctcgggattccggtgaccggt
ggcaacgtgagtttctacaaccaaaccggttcggcggcaatcctgcccacgccggtggtc
ggggtgctcggcgtcatcgacgatgtgcgtcggcgcatccctaccggcctgggcgccgag
cccggggaaacgttgatgctgttgggcgacacccgcgacgagttcgacggttccgtgtgg
gcgcaggtgaccgcagaccacctgggtggattgccgccggtagtcgatctggcgcgggag
aagctgctggccgcggtgctgagctcggcgtcgcgggacgggctagtgtccgcggcgcac
gatctgtccgagggtgggctggcccaagccatcgtggaatcggcgttagcgggtgaaacc
ggttgccgcatattgcttcccgaaggggctgacccgtttgtgctgctgttctccgagtcg
gcgggtcgggtgctggtcgcggtgccacgcaccgaggagagccggtttcgcgggatgtgt
gaggcgcggggacttcccgcggtccgcatcggcgtcgtcgatcaaggttcggacgcggtt
gaggtgcagggcttgttcgcggtgtcgttggccgaactgcgtgcgacatccgaggcggtg
ttgccgcgatacttcggatga
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