KEGG   Mycobacterium tuberculosis EAI5: M943_12650
Entry
M943_12650        CDS       T02749                                 
Name
(GenBank) dihydrofolate synthase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
mtx  Mycobacterium tuberculosis EAI5
Pathway
mtx00790  Folate biosynthesis
mtx01100  Metabolic pathways
mtx01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:mtx00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    M943_12650
Enzymes [BR:mtx01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     M943_12650
    6.3.2.17  tetrahydrofolate synthase
     M943_12650
SSDB
Motif
Pfam: Mur_ligase_C Mur_ligase_M
Other DBs
NCBI-ProteinID: AGQ35729
LinkDB
Position
complement(2735285..2736748)
AA seq 487 aa
MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSP
QRSYPSIHIAGTNGKTSVARMVDALVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQY
VATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAFAAFADAPVDVAVVEVGMGGR
WDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPK
VMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAH
NAVLALASVEAFFGAGAQRQLDGDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGAS
ALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFDSVVVTHNGSPRALDVEALALA
AGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAGDAFSRTGIVITGSVVTAGAART
LFGRDPQ
NT seq 1464 nt   +upstreamnt  +downstreamnt
atgaattcgacgaattccggcccgcctgactcgggatcggccaccggcgtcgtgcccact
ccggacgagatcgcgtccctgctgcaggttgagcatctactcgaccaacgctggccggag
acccgcatcgatccgagcctgacccggatcagcgcgttgatggacctgctgggctcgccc
caacgcagctatccgtcgatccatatcgcgggcaccaacggcaagacctcggtggcgcgc
atggtcgacgcgctggtcaccgcgctgcaccggcgcaccggccgaaccaccagcccacac
ctgcagtcaccggtggaacgcatttcgatcgacggcaagccgatcagcccggcgcagtat
gtggcgacctaccgggagatcgagccgttggtggcgctgatcgaccagcagtcgcaggct
tctgcgggtaagggtggcccggcgatgagcaagttcgaggtgctcaccgcgatggcgttc
gcggcctttgcggacgcgcccgtcgacgtggcagtggtcgaggtgggcatgggcggacgt
tgggacgccaccaacgtgatcaacgcaccggtcgccgtcatcaccccgatcagcattgat
cacgtcgactatctcggtgccgatatcgccgggatcgccggggagaaggcgggcatcatc
actcgggcccccgacggttcgccggacaccgtcgcggtcatcgggcgtcaggtcccgaag
gtcatggaggtgctgctggccgaatcggtgcgcgccgacgcgtcggtggcccgggaggat
tccgaattcgcggtgctacggcgacagatcgcggtcggcggtcaggtactgcaactgcag
ggcctcggcggggtttactccgacatctacttgccgctgcacggtgaacaccaggcgcac
aacgcggtgctcgccctcgcttccgtcgaggcctttttcggtgccggtgcgcagcgtcag
ctcgacggcgacgccgtccgggccggctttgccgccgtcaccagtcccggccggttggag
cgcatgcgcagcgcacccacggtgttcatcgacgccgcgcacaatccggccggggcgagt
gctctggcacaaacgctggcgcatgagttcgacttccgatttctggtcggggtgctcagc
gtgctgggcgacaaggacgtggacggcatcctggccgcactggagccggtgttcgattcc
gtcgtcgtgacccacaacgggtcgccgcgggcgctggatgtcgaggccctggcgctggcg
gccggcgagcggttcggacccgaccgggtgcgcaccgccgagaacctgcgcgatgctatc
gacgttgccacctcactggtcgacgacgccgccgccgacccggatgtggccggggacgca
ttctcgagaaccgggatcgtcatcaccggctcggttgtcaccgcaggggcggctcggacc
ttgttcggtcgtgatccgcaatga

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