Mycobacterium tuberculosis EAI5: M943_18185
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Entry
M943_18185 CDS
T02749
Name
(GenBank) 3-ketosteroid-delta-1-dehydrogenase
KO
K05898
3-oxosteroid 1-dehydrogenase [EC:
1.3.99.4
]
Organism
mtx
Mycobacterium tuberculosis EAI5
Pathway
mtx00984
Steroid degradation
mtx01100
Metabolic pathways
mtx01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mtx00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
M943_18185
Enzymes [BR:
mtx01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.99 With unknown physiological acceptors
1.3.99.4 3-oxosteroid 1-dehydrogenase
M943_18185
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Gene cluster
GFIT
Motif
Pfam:
FAD_binding_2
FAD_oxidored
DAO
HI0933_like
NAD_binding_8
Thi4
FAD_binding_3
Pyr_redox_2
Pyr_redox_3
GIDA
Pyr_redox
Lycopene_cycl
DUF6506
GDI
Motif
Other DBs
NCBI-ProteinID:
AGQ36673
LinkDB
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Position
3954995..3956695
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AA seq
566 aa
AA seq
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MFYMTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVEKAPHYGGSTARSGGGVWIPNNE
VLKRRGVRDTPEAARTYLHGIVGEIVEPERIDAYLDRGPEMLSFVLKHTPLKMCWVPGYS
DYYPEAPGGRPGGRSIEPKPFNARKLGADMAGLEPAYGKVPLNVVVMQQDYVRLNQLKRH
PRGVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVELNTAFTDLFVENG
VVSGVYVRDSHEAESAEPQLIRARRGVILACGGFEHNEQMRIKYQRAPITTEWTVGASAN
TGDGILAAEKLGAALDLMDDAWWGPTVPLVGKPWFALSERNSPGSIIVNMSGKRFMNESM
PYVEACHHMYGGEHGQGPGPGENIPAWLVFDQRYRDRYIFAGLQPGQRIPSRWLDSGVIV
QADTLAELAGKAGLPADELTATVQRFNAFARSGVDEDYHRGESAYDRYYGDPSNKPNPNL
GEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAAGNVSAPVMGHTYPG
PGGTIGPAMTFGYLAALHIADQAGKR
NT seq
1701 nt
NT seq
+upstream
nt +downstream
nt
gtgttctacatgactgtgcaggagttcgacgtcgtggtggtcggcagcggcgccgccggc
atggttgctgcgctggtcgccgctcaccgaggtctctcgacggtagtcgtcgagaaggcc
ccgcactacggcggctccaccgcacgctcgggcggcggcgtctggatccccaacaacgag
gtcctcaagcgccgcggcgttcgagatacaccggaggcggcacgcacctatctgcacggc
atcgtcggcgaaatcgtcgagccggaacgcatcgatgcttacctcgaccgcgggcccgag
atgctgtcgttcgtgctgaagcacacgccgctgaagatgtgctgggtacccggctactcc
gactactaccccgaggctccgggcggccgcccgggcggacgttcgatcgagccgaaaccg
ttcaacgcgcgcaagcttggtgccgacatggccgggctggagcccgcgtatggcaaggtt
ccgctcaatgtggttgtgatgcagcaggactacgttcgcctcaatcagctcaaacgtcac
ccccgtggcgtgctgcgcagcatgaaggtcggcgcccgcacgatgtgggcgaaggcaaca
ggtaagaacctggtcggcatgggtcgagccctcattgggccgttgcggatcgggttgcag
cgcgccggagtgccggtcgaactcaacaccgccttcaccgatcttttcgtcgaaaatggc
gtcgtgtccggggtatacgtccgcgattcccacgaggcggaatccgctgagccgcagctg
atccgggctcgccgcggcgtgatcctggcctgtggtggtttcgagcataacgagcagatg
cgaatcaagtaccagcgggcacccatcaccaccgagtggaccgtgggcgccagcgccaat
accggtgacggcattctcgccgccgaaaagctcggcgcagcactggatctgatggatgac
gcttggtggggcccgacggtaccgctggtcggcaaaccatggttcgcgctctcggagcgc
aactctcccggttcgatcatcgtcaacatgtcaggcaagcgattcatgaacgaatcgatg
ccatacgtcgaagcctgtcatcatatgtacggcggcgaacacggccaggggcccggaccg
ggcgagaacattccggcgtggctggtgttcgaccagcgataccgggaccgctacatcttc
gcgggactacaaccagggcaacgcattccgagcaggtggctggattccggcgtcatcgtc
caggccgatacccttgcggagctggccggcaaggccggtctacccgcggacgaactcact
gccaccgtccagcgtttcaacgcattcgcccggtccggtgtcgacgaggactaccaccgc
ggggaaagtgcctacgatcgctactacggcgacccgagcaacaagcccaatccgaacctc
ggcgaggtcggccacccgccctattatggcgccaagatggttccgggcgacctggggacc
aagggcggtatccgcaccgatgtcaacggacgtgctctgcgggacgacggcagcatcatc
gacggcctttacgctgcaggcaatgtcagtgccccagtgatgggacacacctaccccggt
ccgggcggcacgataggcccggcgatgacgttcgggtacctggcggcgctgcacattgcc
gatcaggcgggaaagcgctga
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