Mycobacterium tuberculosis KZN 605: TBXG_000269
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Entry
TBXG_000269 CDS
T02141
Name
(GenBank) 5-oxoprolinase oplA
KO
K01469
5-oxoprolinase (ATP-hydrolysing) [EC:
3.5.2.9
]
Organism
mtz
Mycobacterium tuberculosis KZN 605
Pathway
mtz00480
Glutathione metabolism
mtz01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
mtz00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
TBXG_000269
Enzymes [BR:
mtz01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.9 5-oxoprolinase (ATP-hydrolysing)
TBXG_000269
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Gene cluster
GFIT
Motif
Pfam:
Hydantoinase_B
Hydantoinase_A
Hydant_A_N
Hydant_A_C
PucR-like_N
Motif
Other DBs
NCBI-ProteinID:
AFM47650
LinkDB
All DBs
Position
complement(317464..321093)
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AA seq
1209 aa
AA seq
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MVGAGWHFWVDRGGTFTDVVARRPDGRLLTHKLLSDNPARYRDAAVAGIRALLANGEAGT
RVDAVRMGTTVATNALLERTGERTLLVITRGFGDALRIAYQNRPRIFDRRIVLPEMLYER
VVEVDERVTADGRVLRAPDLEALGEKMRQAHADGIRAVAVVCLHSYLYPGHEREIGTLAQ
RIGFAQISLSSEVSPLMKLVPRGDTTVVDAYLSPVLRRYINQVADQMRGVRLMFMQSNGG
LAQAGHFRGKDAILSGPAGGIVGMVRMSALAGFDHVIGFDMGGTSTDVSHYAGEYERVFT
TQVAGVRLRAPMLDIHTVAAGGGSILHFDGSRYRVGPDSAGADPGPACYRGGGPLCVTDA
NVMLGRIQPTHFPSVFGPSGDQPLDAGTVRRGFTDLAADIAARTGDDRSPEQVAEGYLRI
AVANMANAVKKISVQKGHDVTRYALTTFGGAGGQHACAVADALGIRTVLIPPMAGVLSAL
GIGLADTTAMREQSVEIPLGPAAPQRLASVAESLERAARAELLDEGVPGERIRVVRRVHL
RYEGTDTAIPVQLAEIETMATAFESSHRALYTFLLDRPLIAEAISVEATGLTDQPDLSQL
GDQANDTTGSSETVRIYSNGLWRDAPLRRREAMRPGDVLTGPAIIAEANATTVVDDGWQA
TMTETGHLLAQRVVTPPRPDAATRAGFEAGFEADPVLLEIFNNLFMSIAEQMGFRLEATA
QSVNIRERLDFSCALFDPDGNLVANAPHIPVHLGSMGTTVKEVIRRRLSGMKPGDVYAVN
DPYHGGTHLPDITVITPVFNTGGEDVLFFVASRGHHAEIGGITPGSMPADSREIHEEGVL
FDNWLLAENGRFREAETRRLLTEAPFGSRNPDTNLADLRAQIAANQKGVDEVGKMIDHFG
RDVVAAYMRHVQDNAEEAVRRVIDRLDNGAYRYRMDSGATIAVRITVDRAARSATIDFTG
TSAQLDTNFNAPTSVVNAAVLYVFRTLVADDIPLNDGCLRPLRIVVPEGSMLAPTHPAAV
VAGNVETSQAITGALFAALGVQAEGSGTMNNVTFGNERHQYYETVGSGSGAGDGYHGASV
VQTHMTNSRLTDPEVLEWRYPVLLREFAVRQGSGGAGRWRGGDGAVRRLEFTEPMTVSTL
SGHRRVRPYGMAGGSPGELGRNRVERADGSTVELAGCGSTHVEPGDTLVIETPGGGGYGP
ASTSARRRR
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
gtggttggcgcggggtggcacttctgggtcgaccggggtggcacgttcaccgacgttgtg
gcgcgccggccggacggacggctgctgacccacaagctgctgtcggacaacccggcacgc
tatcgcgacgccgcggtggccggcatccgtgcgctgctagcgaacggcgaggcgggcacg
cgcgtcgacgcggtgcggatgggcaccacggtggcgaccaatgcgttgctcgagcgcacg
ggtgagcgcacactgctggtgatcacccgcggtttcggcgacgccctgcgcatcgcctac
cagaatcgtccgcgcatcttcgaccggcggatcgtgttgcccgagatgctttatgagcgg
gtcgtcgaggtcgatgaacgggtcacagccgacggccgggtgctgcgggcacccgacctg
gaggcattgggcgagaagatgcggcaggcccatgcggacggaatccgcgcggtcgcggtg
gtgtgcctgcacagttacctctacccgggacacgagcgagaaatcggtacgctggcgcag
cgcatcggcttcgcccagatctcgttgtcatctgaggtcagcccgctgatgaaactggtc
ccgcgcggggataccaccgtggtcgacgcctacttgtccccggtgctgcgccgatacatc
aaccaggtggccgaccagatgcggggtgtgcgactgatgttcatgcagtccaacgggggg
ctggcgcaggccgggcacttccgcggcaaggacgcgattctgtctggtccggccggcggc
atcgtcggcatggtgcggatgtcggcgctggccggcttcgatcatgttattggcttcgac
atgggcggcacctcgaccgacgtgtcgcactacgccggcgagtacgaacgcgtcttcacg
acccaggttgccggggtccggctgcgcgcgccgatgctggacatccacacggtggccgcc
ggcggcgggtcgattctgcatttcgacgggagccgctaccgagtcggcccggactcggcc
ggagccgaccccggcccggcctgctaccgcggcggcggaccgctgtgcgtcaccgacgcc
aacgtgatgctcggccgcatccagcccacccacttcccgtccgtattcggtccttccggc
gaccagccgctggacgccgggaccgtgcggcgtggcttcaccgacctggccgccgacatc
gccgcgcggaccggcgacgaccggtcacccgagcaggtcgccgagggatatctgcggatc
gcggtggcgaacatggccaacgcggtcaaaaagatctccgtgcaaaagggacacgacgtg
acgcggtacgcgctgacgacgttcggcggcgccggcggtcagcacgcatgtgcggtggcc
gacgccctcggcatccgcacggtgctgatcccaccaatggccggcgtgctttccgcgctg
gggatcggcctggccgacaccaccgcaatgcgcgaacaatcggtggagatcccgctcgga
cccgccgcgccacagcgtttggccagcgttgcggaatccctcgaacgagccgcccgcgcc
gagttgctggacgagggcgtcccgggtgagcgcatccgggtggttcgccgggtgcacctg
cgctatgagggaaccgataccgcgatccccgtgcaactggccgagatcgagaccatggcc
acggcgtttgaaagcagccaccgcgcgctgtacacgttcctgctggatcgtccgctgatc
gccgaagcgatctcggtcgaggcgaccgggctcaccgaccagcccgacctgtcccagctg
ggcgatcaggccaacgacaccaccggctcgtcggaaaccgtgcggatctattcgaacgga
ttgtggcgcgacgcaccgctgcggcgtagggaggcgatgcggccgggcgacgtgctgacc
ggtccggcgatcatcgccgaggccaacgccaccaccgtcgtcgacgacggctggcaggcg
acgatgacggagaccgggcacctgctcgcgcaacgagtggtcaccccgccgcggcccgat
gcggccactcgggccggtttcgaggccggtttcgaggccgacccggtgctgttggagatc
ttcaacaacctgttcatgtcgatcgccgagcagatgggcttccggctggaagccaccgcc
cagtcggtgaacatccgggagcggctggacttctcctgcgcgctgttcgatccggacggc
aacctggtcgccaacgccccgcacattccggtgcacctcggctcgatgggcaccaccgtc
aaggaagtgatccgccggcgcttgagcggcatgaagcccggtgacgtatacgccgtcaac
gacccgtaccacggcggcacccacctgccggacatcacagtgatcaccccggtgttcaac
accggcggcgaggacgtcctattctttgtcgcctctcgcgggcaccacgccgaaatcggc
ggcatcacccccggctccatgcccgccgacagccgcgagatccacgaagagggcgtgctg
ttcgacaactggctgctcgccgagaacggacggttccgcgaggccgaaacccggcgcctg
cttaccgaggcgccgttcggttcccgcaatcccgacaccaacctcgccgatctgcgcgcg
cagatcgccgccaaccaaaagggcgtcgacgaggtcggaaaaatgatcgaccacttcggc
cgcgacgtggtggcggcctacatgcgccacgtccaggacaacgccgaggaagcggtccgc
cgggtcatcgaccggctcgacaacggcgcctaccgctaccgcatggattcgggcgcgacg
atcgccgtgcgcatcaccgtcgaccgcgccgcccgcagcgcgaccatcgacttcaccgga
acctcggctcagctggacaccaacttcaacgcaccgacctcggtggtgaatgcggcggtg
ctctacgtgttccggaccctggtcgccgacgacatcccgctcaacgacggttgcctgcgc
ccgttgcgtatcgtcgtccccgaaggctcgatgctcgcaccaacccatcccgccgcggtg
gtcgctggcaacgtcgaaacctcgcaggcgatcaccggcgcgctgttcgccgcgttgggt
gtgcaggccgagggatccgggacgatgaacaacgtcacgttcggcaacgagcggcaccag
tactacgaaaccgtaggatcgggctccggggccggtgacgggtaccacggggcctcggtg
gtgcagacgcacatgaccaactcccggctcaccgatcccgaggtgctggagtggcgctac
ccggtgttgctgcgcgagttcgccgtacgtcagggcagcgggggcgccggtcgctggcgg
ggcggcgacggcgccgtccgacgcctcgagttcaccgagccgatgacggtcagcacgctc
tccggtcatcggcgggttcggccctacggcatggccggcggctcccccggagagctggga
cgcaaccgagtggaacgcgccgacggcagcaccgtcgagttggccggatgcggctcaacg
cacgtcgagccgggcgacacgctggtgatcgaaacccccggcggcggcggatacgggcca
gcaagtaccagcgcccgacgccggcggtaa
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