Mycobacterium ulcerans: MUL_0654
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Entry
MUL_0654 CDS
T00435
Symbol
menD
Name
(GenBank) bifunctional 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, MenD
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
mul
Mycobacterium ulcerans
Pathway
mul00130
Ubiquinone and other terpenoid-quinone biosynthesis
mul01100
Metabolic pathways
mul01110
Biosynthesis of secondary metabolites
mul01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mul00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
MUL_0654 (menD)
Enzymes [BR:
mul01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
MUL_0654 (menD)
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GFIT
Motif
Pfam:
TPP_enzyme_N
Motif
Other DBs
NCBI-ProteinID:
ABL03318
Pasteur:
MUL_0654
UniProt:
A0PLU9
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Position
676145..677791
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AA seq
548 aa
AA seq
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MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGF
LAIGLAVGAGAPACVAMTSGTAVANLGPAVVETNYARVPLIVLSANRPYELLGTGANQTM
EQLGYFGTQVRATISLGLAEDAHERLDSLNASWRSATCRMLAAAMGSRTANAGPVHFDIP
LREPLVPDPDPHGAVTPPGRPEGRPWTYTPPVTFDQPLEIDLSADTVVIAGHGAGVHPNL
VQLPTIAEPTAPAAPSGGNPLHPLALPLLRPRQVIMLGRPTLHRPVSALLADPEVPVFAL
TTGPRWPDVSGNSQATGTRAIVTGTPNPSWLDRCAQMNRHAVAAVREQLAAHPLTTGLHV
AAAVAGALRPGDQLVLGASNPVRDAALVGLDTAGLRVRSNRGVAGIDGTVSTAIGAALGY
ERDHHGRTVALIGDLTFVHDSSGLLIGPTEPTPRQLTIVVSNDNGGGIFELLEQGDPRFS
DVSSRIFGTPHDVDVGALCRAYHVENRQIEVDQLPAALDEPGSGLRVLEVKADRSSLRQL
HAAIKAAL
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccttcgacgacacaggcccgcgttgtcgttgacgagttgatccgcggtggggtt
cgcgatgtggtgctgtgccccggctcgcgcaacgcgccgctggccttcgcgttgcaggac
gccgaccggtccggtcgcattcggctgcacgttcgcatcgacgaacgcaccgccggcttc
ttggccatcgggctggccgtcggggcgggtgcgccggcgtgtgtggcgatgacctccggt
accgcggtggccaatctcggcccggcggtggtggagaccaattacgcccgggtgccgctg
atcgtgctctcggcgaaccggccctacgaactgctgggcaccggggccaaccagaccatg
gagcaactgggctacttcggcactcaagtgcgtgccacgatcagcctgggtctggccgag
gatgcgcacgaacgcctggactccctcaacgcgtcgtggcgatcggccacgtgccggatg
ctggcggccgccatggggtcgcgtaccgccaacgccggcccggtgcactttgacattccg
ttgcgggaaccgctggtgcccgacccggacccccacggtgcggtgaccccgccgggacgc
ccggagggccggccgtggacctacaccccaccggtcaccttcgaccaaccgctggaaatc
gacctgtccgccgacaccgtcgtcatcgccgggcacggcgccggtgtgcaccccaacctg
gtgcagctacccaccatcgccgagccgacagcaccggctgcgccgtccggtggcaaccct
ctgcacccgttggcactgccgctgctgcggccccggcaggtgatcatgctggggcgcccg
acgctgcaccggccggtatcggccttgctggccgatcccgaagtgccggtctttgcgttg
acgaccgggccccgctggccggatgtgtcgggaaactcgcaggccaccggaacccgggcg
atcgtcaccggcaccccgaacccgtcgtggctggaccgctgcgcgcagatgaaccgccac
gcggttgcggcggtacgcgagcagcttgccgcgcacccgctgaccaccggcctgcacgtc
gcggcggccgttgccggcgcgcttcgccccggcgaccagctggtgctgggcgcgtccaac
ccggtgcgcgatgcggccctggtcggcctggacactgcgggcctgcgggtgcgatccaat
cgcggggtcgccggtatcgacggcaccgtgtccacggccatcggggccgcgctgggctac
gaacgcgatcatcacgggcgcaccgtcgcgctgatcggtgatttgacgttcgtccacgac
agctccggcttgttgatcggccctaccgaaccgacaccgcggcagctgacgatcgtggtg
tccaacgacaatggcggcggcatttttgagctgctcgagcagggggatccgcggttctcc
gatgtctcgtcgcggatcttcggcaccccccacgacgtcgacgtgggcgcactgtgccgg
gcctaccacgtggagaacaggcagatcgaagtggaccagttgccggccgcgctggacgag
ccgggcagcggcctgcgggtgctcgaggtcaaggcggaccgctcctcgctgcggcaactg
cacgccgccatcaaggccgcgctatga
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