KEGG   Mycobacterium ulcerans: MUL_1949
Entry
MUL_1949          CDS       T00435                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase IlvC
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
mul  Mycobacterium ulcerans
Pathway
mul00290  Valine, leucine and isoleucine biosynthesis
mul00770  Pantothenate and CoA biosynthesis
mul01100  Metabolic pathways
mul01110  Biosynthesis of secondary metabolites
mul01210  2-Oxocarboxylic acid metabolism
mul01230  Biosynthesis of amino acids
Module
mul_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mul_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:mul00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MUL_1949 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    MUL_1949 (ilvC)
Enzymes [BR:mul01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     MUL_1949 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C NAD_binding_2 F420_oxidored NAD_binding_7 AdoHcyase_NAD VirD1
Other DBs
NCBI-ProteinID: ABL04402
Pasteur: MUL_1949
UniProt: A0PPY3
LinkDB
Position
2154651..2155652
AA seq 333 aa
MFYDDDADLSIIEGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKEGSKSRAKVEEQGIE
VDTPAKVAEWADVIMVLAPDTAQAEIFANDIEPNLKPGDALFFGHGLNVHFGLIKPPADV
TVAMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGKGEALALSYAKAIGGTRAGVIKTT
FKDETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYPPEMAYFEVLHELKLIVDLMYEGG
IARMNYSVSDTAEFGGYLSGPRVIDAGTKERMRAILRDIQSGDFVKKLVANVEGGNKQLE
ALRKENAEHSIEVTGKKLRDLMSWVDRPITETA
NT seq 1002 nt   +upstreamnt  +downstreamnt
atgttctacgacgatgacgccgacctttcgatcatcgagggccgcaaggtcggtgtgatc
ggctacggcagccagggacatgcgcactcgctgagtctgcgcgactcgggtgtccaggtg
cgggtcgggctcaaagagggctcgaagtcgcgggccaaggtcgaggagcagggcatcgag
gtcgatacgccggccaaggtggccgagtgggccgacgtcatcatggtgctggcacccgac
accgcccaggccgagatctttgccaacgacatcgagcccaacctcaagcccggtgacgcc
ttgttcttcggtcacggcctcaacgtccacttcggcctgatcaagccgccggccgacgtc
accgtggccatggtggccccgaaggggcccggccacctggtgcgccgtcagttcgtcgac
ggcaagggcgtgccgtgtctgatcgcggtcgaccaggacccgaccggcaagggtgaggcg
ctggcgttgtcctatgccaaggcgatcggcggcactcgggccggcgtcatcaagaccacc
ttcaaagacgagaccgagaccgacctgttcggcgaacaggccgtgttgtgcggtggcaca
gaggaactggtgaagaccggtttcgacgtgatggtcgaggcgggctacccgccggagatg
gcctacttcgaggtgctgcacgagctcaagctgatcgtcgacctgatgtacgagggcggc
atcgcccggatgaactactcggtgtcggacaccgcggagttcggtggctacctgtccggt
ccgcgcgtgatcgacgcgggcaccaaggagcggatgcgcgccatcttgcgcgacatccag
agcggcgacttcgtcaagaagctggtcgccaacgtcgagggcggcaacaagcaactcgag
gcgctgcgcaaggagaacgccgagcactcgatcgaggtcaccggtaagaagctgcgcgac
ctgatgagctgggtggaccgcccgatcaccgagacggcctag

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