Mycobacterium ulcerans: MUL_1968
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Entry
MUL_1968 CDS
T00435
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase (large subunit) LeuC
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mul
Mycobacterium ulcerans
Pathway
mul00290
Valine, leucine and isoleucine biosynthesis
mul00660
C5-Branched dibasic acid metabolism
mul01100
Metabolic pathways
mul01110
Biosynthesis of secondary metabolites
mul01210
2-Oxocarboxylic acid metabolism
mul01230
Biosynthesis of amino acids
Module
mul_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mul00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MUL_1968 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MUL_1968 (leuC)
Enzymes [BR:
mul01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MUL_1968 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MUL_1968 (leuC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ABL04415
Pasteur:
MUL_1968
UniProt:
A0PPZ6
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All DBs
Position
2175142..2176563
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AA seq
473 aa
AA seq
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MALQTREARTLAEKVWDDHVVVSGRNEAPDLIYIDLHQVHEVTSPQAFDGLRLAGRPVRR
PDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDVEQGIVHVVGP
QLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLWPFKTMAVNVDGQ
LPAGVSAKDIILALIAKIGTGGGQGHVIEYQGSAIESLSMEGRMTICNMSIEAGARAGMV
APDETTYEYLRNRPHAPTGAQWDAALGYWQQLRTDPGAVFDTEVHLDAAELSPFVTWGTN
PGQGVPLCATVPDPELIGDDGERQAAEKALAYMDLEPGKAMRDIAVDAVFVGSCTNGRIE
DLRVVAEVLRGRKVAPGVRMLIVPGSMRVRAQAEKEGLGEVFTVAGAEWRQAGCSMCLGM
NPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLN
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atggcactgcagacgcgcgaggcgcgcacgctggctgagaaggtctgggacgaccacgtc
gtggtgtccggtcggaacgaggctcccgacctgatctacatcgatctgcatcaggtgcat
gaggtcaccagcccgcaggcattcgatggtctgcgcctggccggccgcccggtgcgacgg
cccgatctgaccatcgccaccgaggatcacaatgtgccgaccgtcgatatcgataagccg
atcgccgacccggtgtctcggacccaggtggagacattgcggcgtaattgcgcggaattc
ggcatccggctgcaccccatgggtgatgtcgagcagggcatcgtgcacgtcgtgggacct
cagttgggcctcactcagccgggaatgaccatcgtctgtggtgacagccacacttcgacc
catggcgcgttcggtgccttggcgatgggcatcggcacttccgaagtcgagcatgtgctc
gcaacacagacgctgccgttgtggccgttcaagacgatggcggtcaatgtggatgggcaa
ctacccgcaggagtgtcggccaaggacatcatccttgcgctgatcgccaagatcggcacc
ggcggtgggcaggggcacgtcatcgaataccagggcagcgccattgaatcgctgtccatg
gaaggccggatgacgatctgcaacatgagcattgaggccggcgcccgagccgggatggtg
gcgccggacgagaccacttacgagtacttgcgaaaccggccacacgccccaaccggtgcc
cagtgggatgccgcgcttgggtactggcaacaactgcggaccgatcctggcgccgtcttc
gacaccgaggtccatctcgacgccgccgagctgagcccctttgttacgtggggaaccaat
cccggccagggcgtgccgctttgcgccacggtgcccgatcccgagctcatcggcgatgac
ggcgagcgccaggccgccgagaaagcattggcgtacatggaccttgagccaggaaaagcc
atgcgcgatatcgcggtcgatgccgtgttcgtcgggtcgtgcaccaacggccggatcgag
gatctgcgggtcgtggccgaagtgctgcgtggccgcaaggtcgccccaggggtgcgaatg
ctcatcgttcccggctccatgcgggtgcgtgcccaggccgagaaggagggcctgggtgag
gtcttcacggtcgcgggcgccgaatggcggcaggcgggatgctctatgtgcctagggatg
aaccccgatcagctcgcgccgggggagcgctgtgcggcgacgtccaaccgcaacttcgag
gggcgccagggcaagggcgggcggacacatttggtctcgccggcggtggccgccgcaacc
gcggttcgcggcaccctatccgcgcctgccgatttgaattga
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