Mycobacterium ulcerans: MUL_3505
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Entry
MUL_3505 CDS
T00435
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mul
Mycobacterium ulcerans
Pathway
mul00300
Lysine biosynthesis
mul00550
Peptidoglycan biosynthesis
mul01100
Metabolic pathways
mul01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mul00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MUL_3505 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MUL_3505 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MUL_3505 (murF)
Enzymes [BR:
mul01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MUL_3505 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABL05660
Pasteur:
MUL_3505
UniProt:
A0PTJ1
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Position
complement(3885157..3886734)
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AA seq
525 aa
AA seq
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MIDYTVAEIAEIVGGTLVDISPQEAEQRRVTGTVEFDSRAVGPGGLFLALPGARADGHDH
AAAAVAAGAVAVLAARPVGVSAIVVSPEPDSTADALTGVLEHDADGSGAAVLAALAKLAK
AVAAELMAGGLTIIGITGSSGKTSTKDLVAAVLKPLGEVVAPPGSFNNELGHPWTVLRAT
RSTDYLILEMSARHPGNIAALARVAPPAIGVVLNVGTAHLGEFGSREIIAQTKSELPQAV
PASGVVILNADDPAVAAMAEVTAARVVRVGRATATGAGWAGPGDVWAGPVSLDRLARPQF
TMHAGDAAAQVRLGVYGDHQVSNALCAGAVALECGASVSQVAAALAEAGPVSRHRMRVST
RPDGVTVIDDAYNANPDSMRAGLQALAWIARGEAESTAASQPGVRPQSRRSWAVLGEMAE
LGADAITEHDHIGRLAVRLDVSRLVVVGTGRSMSAIYHGAVMEGSWGTEAVSVPDRDAAL
ALLRAEIQPGDVVLIKASNSAGLGELADALACADAGCQDRGSAHS
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgatcgactacaccgtcgccgagatcgccgagattgtcggggggacgctggtcgacatc
tcgccgcaagaggctgagcaacggcgggtcaccgggaccgtggagttcgattcgcgggcg
gtcggcccgggcggattgtttctggctctgcccggcgcgcgtgccgacggacacgatcac
gcggcggcggcggtcgcggccggtgccgtcgccgtgctcgccgcccgccccgtcggggtc
tcggcgatcgtggtttcacccgaaccggactcgaccgccgacgcgttgaccggggtgctc
gagcacgacgccgacgggtcgggtgcggccgtgctggccgccctggccaagttggccaag
gctgtggccgcggagctgatggccggcggactgaccatcatcgggatcaccgggtcgtcg
ggcaagacatcgaccaaggatctggtggccgcggtgctcaaacctttgggcgaggtcgtc
gcaccacccgggtccttcaacaacgaactcgggcatccctggaccgtgctgcgtgccacc
cgcagcaccgactacctgattctggagatgtcggcacgccatcccggcaatatcgccgcg
ctggcacgggtggcaccaccggccattggggtggtgctcaacgtcggcaccgcacacctg
ggggagttcggttcacgcgagatcattgcccaaaccaaatctgagctgccgcaagccgtc
ccggcatccggggtggtcatcctcaacgcggatgacccggctgtggcggccatggccgag
gtgactgccgcccgggtggttcgggtgggtagagccaccgccaccggagccggctgggcc
ggtcccggtgatgtctgggcgggaccggtctcgctggatcggctggcccggccgcagttc
accatgcacgccggtgacgccgcggcccaggtacgactcggggtgtacggggaccaccag
gtctccaacgcgttgtgcgccggcgcggtggccctcgaatgcggcgcgagcgtgtcgcag
gtggcggccgcactcgccgaggcggggcccgtgtcgcggcaccggatgcgggtgagcacc
cggccggacggggtgacggtgatcgatgacgcctacaacgccaacccggattccatgcgc
gccgggctgcaggcgctggcgtggatcgcccgcggtgaggcggagtcgaccgccgcgagt
cagcctggtgtccggcctcaaagtcggcgcagttgggcagtgctgggcgagatggctgag
ctcggcgcggacgcgataaccgagcacgatcacatcggcaggctcgccgtgcgcttagat
gtgtctcgactcgttgtcgtgggaactgggaggtcgatgagcgccatataccacggagcg
gtcatggagggttcgtggggcacggaggcggtcagcgtcccggaccgcgacgctgccctg
gcattgttgcgcgcggagatccaacccggagatgtcgtcctgatcaaggcctcgaactcg
gccggcctgggtgagctggccgacgcgctggcttgcgcagacgcaggctgtcaagaccgc
gggagtgcgcactcatga
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