KEGG   Mycobacterium ulcerans: MUL_4300
Entry
MUL_4300          CDS       T00435                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase LeuA
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mul  Mycobacterium ulcerans
Pathway
mul00290  Valine, leucine and isoleucine biosynthesis
mul00620  Pyruvate metabolism
mul01100  Metabolic pathways
mul01110  Biosynthesis of secondary metabolites
mul01210  2-Oxocarboxylic acid metabolism
mul01230  Biosynthesis of amino acids
Module
mul_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mul00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    MUL_4300 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MUL_4300 (leuA)
Enzymes [BR:mul01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     MUL_4300 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: ABL06315
Pasteur: MUL_4300
UniProt: A0PVE6
LinkDB
Position
4776991..4778691
AA seq 566 aa
MPVNRYRPFAEEVEHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFD
LLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFEACAG
ASKVIVHFYNSTSILQRRVVFRADRAAVEAIATDGARRCVEEAAKYPDTQWRFEYSPESY
TGTELEYAKQVCDAVAEVIQPTPENPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV
ILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLATLGLNLFSRGVDPQI
DFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMEFDADAADSD
MDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRA
IQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKI
DGKEAEISGSGNGPLAAFVHALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTV
WGVGIAPSITTASLRAVVSAINRASR
NT seq 1701 nt   +upstreamnt  +downstreamnt
atgccggtcaaccgttaccggccgttcgccgaggaagtcgaacacatccgggttaccgac
cgcacctggcccgaccgcgtcatcgaccgcgcccccctgtggtgcgcggtggacctgcgt
gacggcaaccaggcactgatcgatccgatgagcccggcccgcaagcggcgcatgttcgac
ctgctagttcggatgggttacaaggagatcgaggtcggctttccctcggccagccagacc
gacttcgacttcgtccgcgagatcatcaccgaaggcgccattcccgacgacgtcaccatc
caggtgctgactcagtgccgccccgagctgatcgagcgcacgttcgaggcgtgcgctggg
gcgtcgaaggtgatcgtgcacttctacaactcaacgtcgatcctgcagcgccgcgtggtg
ttccgcgccgaccgggccgcggtagaagcgatcgcgaccgacggcgcccgcagatgcgtc
gaggaagcggccaaataccccgacacccagtggcgcttcgagtactcaccggagtcctac
acgggcaccgagctggaatacgccaaacaggtgtgcgacgcggtggccgaagtcatccag
cccaccccggaaaacccgatcatcttcaatctgcccgccactgtggagatggccaccccg
aacgtctacgccgactcgatcgagtggatgagccgcaacctggccaaccgggagtcggtc
attctgagcctgcatccccacaacgatcgcggaaccgccgtcgccgcagccgaattgggc
ttcgccgcaggcgccgaccggatcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtgtgtctggcgaccctggggctgaacctgttctcccgcggcgtggacccgcagatc
gatttctccaacatcgacgagatccggcgcaccgtggagtactgcaaccagctgccggtg
cccgaacgtcacccctacggcggggacctggtctacaccgcgttctccggcagccaccag
gacgccatcaacaagggcctggacgcgatggagttcgatgccgacgctgccgattccgac
atggacgacatgctgtggcaggtgccctacctgcccatcgaccccaaggacgtcggacgc
acctacgaagcggtgatccgagtcaactcgcagtccggcaagggtggggtggcctacatc
atgaaggccgaccacggcctggccctgccacgacggctgcagatcgagttctcgcgcgcg
atccaagagatcgccgagggcagcgcgggcgaagggggcgaggtctcgcccaaagagatg
tgggacgcgttcgccgaggagtacctggcgccggtgcgcccgctggagcggatcaaacag
cgcgtcattgccgccgaggaagatggcggcaccaccagcatcgacgccaccgtcaagatc
gacgggaaagaggccgagatcagtggctcgggcaacggtccgctggccgcgttcgttcac
gcgctgggcaccgtcgggttcgacgtggccgtgttggactactccgagcacgcgatgagc
gccggcgacgacgctcaggcggcggcgtacgtggaggcctccgtggccggcaagacggtg
tggggcgtgggcatcgcgccgtcgatcaccaccgcgtcactgcgggccgtcgtgtcggcg
atcaaccgggcgtcgcgctag

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