Meriones unguiculatus (Mongolian gerbil): 110539471
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Entry
110539471 CDS
T05884
Symbol
Srd5a2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00140
Steroid hormone biosynthesis
mun01100
Metabolic pathways
mun05215
Prostate cancer
Module
mun_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
110539471 (Srd5a2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
110539471 (Srd5a2)
Enzymes [BR:
mun01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
110539471 (Srd5a2)
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
110539471
NCBI-ProteinID:
XP_021481997
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Position
1:105003504..105068905
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AA seq
250 aa
AA seq
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MQMCHQVPVLAGSITLATMGTLNLCRPEPASYGKYLSNTVPFLPARVAWFLQELPAFVVS
VGMLAWQPRSLFGPPGNVLLGLFCIHYFHRTFIYSLLTKGRPFPALIFLRAAAFCTGNGV
LQAYYLIYCAEYPEEWYTDARFCFGVLLFVLGMGVNIHSDHLLRQLRKPGEVTYKIPQGG
LFTYVSGANYLGEIIEWMGYALAAWSVPALAFAFFSLCFLGIRAFNHHRFYLKMFKDYPK
SRKALIPFIF
NT seq
753 nt
NT seq
+upstream
nt +downstream
nt
atgcagatgtgccatcaggtcccggtgctggcaggtagcattactttggccaccatgggc
accctgaacctgtgcagaccggaacctgccagttacgggaaatacctcagcaacaccgtt
cccttcctgcccgcgcgcgtcgcctggttcctgcaggagctgcctgccttcgtggtgtcc
gtagggatgctcgcttggcagccccgctccctcttcggaccgccggggaacgtgctgctg
ggtctcttctgcatacattacttccacaggacatttatttactctttgctcaccaaaggg
aggccttttccagcgctgatctttttgagggcggctgccttctgcacagggaatggagtc
cttcaagcctactacctaatttactgcgcggaatacccggaggagtggtacacagatgct
cggttttgcttcggtgtcctcctgtttgttttgggaatgggggtcaacatccacagtgat
cacctgctgcgccagcttaggaagcctggagaagtcacctacaagattccacaaggtggc
ttgtttacctatgtctccggagccaactacctgggtgagatcattgagtggatgggctat
gccttggctgcttggtccgttccagccctggcttttgcatttttctcactttgtttcctt
gggattcgagcttttaaccaccacaggttctacctcaagatgtttaaggattaccccaaa
tccaggaaagcccttattccattcatcttttaa
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