Meriones unguiculatus (Mongolian gerbil): 110540896
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Entry
110540896 CDS
T05884
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00230
Purine metabolism
mun01100
Metabolic pathways
mun04927
Cortisol synthesis and secretion
mun04934
Cushing syndrome
mun05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110540896 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
110540896 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110540896 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110540896 (Pde8b)
Enzymes [BR:
mun01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
110540896 (Pde8b)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
Motif
Other DBs
NCBI-GeneID:
110540896
NCBI-ProteinID:
XP_060241565
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All DBs
Position
6:complement(67937781..68150922)
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTSSLSQGPTAPLHGLFVQTDAADAMPPSRAPG
PPGAVRVRRSRAELGSGSSTGSSGPAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQSWNFDAEAVCRSIRATNPSEHTVILAVVSQVSDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINACIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTADSNKQIHRIHRDSGDNAQTEPHLFRHKSRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHTQLSMPIAI
NDVPPSVAQLLDNEESWDFNVFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTEATLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDHLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDAKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCDCNPTGKNLPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRSTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcgcagagcggcgtgatctactgccgggactcg
gatgagtccaactcgccccgccagaccagcagcctgtcgcagggccccacggcgcccctg
cacggcctcttcgtgcagaccgacgccgccgacgccatgcccccgagccgcgcgcctgga
cccccgggcgccgtccgcgtccgcaggtcccgggccgagctgggcagcggcagcagcacc
gggtcctcgggccccgccgcgaccacctgccggggccggaggcgccactgctgcagcagc
gccgaggccgagacccagaccagctacaccagtgtcaagcaggtgtcttctgcggaggta
cgcattgggcccatgagactgacacaggaccctatccaggttttgctaatctttgcaaag
gaagatagccagagtgatggcttctggtgggcctgtgacagagctggctatagatgcaac
attgcccgcactccagagtcggccctggagtgctttctggacaagcatcatgaaattatc
gtgattgatcacaggcaaagctggaacttcgatgcagaagcggtgtgtaggtcaatccgg
gccacaaacccctctgagcacacagtgatcctggccgtggtttcacaagtatctgatgac
catgaagaggcctcagttctccctcttctccatgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaaattacgggcctgtaactcagtgtttacagcgttagaccactgccatgaa
gccatagaaataacaagcgatgaccatgtgattcagtatgtcaaccctgcctttgagagg
atgatgggctaccacaaaggggagctcctggggaaagaactcgctgacctacctaagagt
gacaagaaccgggcagatctcctggacaccatcaatgcgtgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaag
atcaccccggtgattggccaaggagggaaaattaggcattttgtctccctcaagaagctg
tgctgtaccgctgacagtaacaagcagattcacaggattcatcgtgattctggggacaat
gctcagacagagcctcatttgttcagacacaagagcaggaggaaagagtccattgatgtg
aaatcaatatcttcccgaggcagtgatgcaccaagcctacagaatcgccgctacccctcc
atggcaaggatccactccatgaccattgaggcccccatcacaaaggttataaatataatc
aatgcagctcaagaaaacagtccagttacagtagcagaagccttggacagagttctagag
attttgcggaccacagaactgtactcccctcagctgggaaccaaagatgaagaccctcac
accagcgatcttgttggaggcctgatgactgatggcttaagaagattatcagggaatgag
tatgtgtttacaaagaatgtccaccagagccacactcagctctccatgcccatcgccatc
aatgatgtcccccctagtgtcgcccagctactagacaacgaggagagttgggacttcaac
gtctttgaattggaagcagttacccataaacggcctctggtgtacttgggcttaaaggtc
ttctctcggtttggagtatgtgagtttttaaactgtactgaagccacccttcgggcctgg
ctgcaagtgatcgaagccaactaccactcttccaacgcctaccacaactccacccacgct
gctgacgtcctgcacgccacagccttcttcctcggaaaggagcgggtgaagggaagcctc
gatcacctggatgaggtggctgcactgattgctgccacggtccatgacgtggatcaccct
ggaagaaccaactccttcctgtgcaacgcaggcagcgagctggccgtgctctacaacgac
accgctgtcttggagagccaccacactgccctggccttccagctcacggtcaaggatgcc
aaatgtaacatcttcaagaatatcgacaggaaccattatcgcacactgcgccaggctata
atcgacatggttttggccacagagatgacgaaacactttgaacacgtgaacaaatttgtg
aacagcatcaacaagccactggcagctgagagtgagggcagcgactgtgactgcaaccct
accgggaagaacctccccgaaaaccaaatcctgatcaagcgcatgatgattaagtgtgct
gatgtggccaacccgtgccgccccttggacctgtgcatcgagtgggctggaaggatctcc
gaggagtacttcgcacagactgatgaggagaagaggcaggggcttcctgtagtgatgcca
gtgtttgaccgcagcacctgcagcatccccaagtcccagatctctttcatcgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacatctgccagccctgatgcagcac
ttggccgacaactacaaacactggaagacactggatgacctcaagtgcaaaagtctgcgg
cttccatctgacagctaa
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