Meriones unguiculatus (Mongolian gerbil): 110541861
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Entry
110541861 CDS
T05884
Symbol
Lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun05012
Parkinson disease
mun05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110541861 (Lrrk2)
05022 Pathways of neurodegeneration - multiple diseases
110541861 (Lrrk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mun01001
]
110541861 (Lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mun04131
]
110541861 (Lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mun04147
]
110541861 (Lrrk2)
Enzymes [BR:
mun01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110541861 (Lrrk2)
Protein kinases [BR:
mun01001
]
Serine/threonine kinases: TKL group
LRRK family
110541861 (Lrrk2)
Membrane trafficking [BR:
mun04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
110541861 (Lrrk2)
Exosome [BR:
mun04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
110541861 (Lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_1
LRR_9
Ank_2
Arf
AAA_22
PduV-EutP
G-alpha
AAA_7
MMR_HSR1
T2SSE
AAA_16
nSTAND3
Ank_3
ABC_tran
NACHT
Kdo
Gtr1_RagA
Pox_A32
TrwB_AAD_bind
MobB
TsaE
AAA_29
TniB
Septin
LRR_6
AAA_33
Arm
SRP54
WD40_like
cobW
Motif
Other DBs
NCBI-GeneID:
110541861
NCBI-ProteinID:
XP_060244772
LinkDB
All DBs
Position
8:complement(10846062..10992314)
Genome browser
AA seq
2548 aa
AA seq
DB search
MNFPLSTAFIVSHKFGLRRTMASGACQGCDEEEEEEEALKKLIVRLNNVQEGKQIETLLQ
LLEDLLVFTYSARASKLFEGKNFHVPLLIVLDSYMRVASVQQVGWSLLCKLIEVCPGTLQ
SLIGPQDVGNDWEVLGIHRLILKMLTVHHANVNLSTVGLKALDLLLESGKITLLILDEEC
DIFLLIFDAMNTYSANGEVQKLGCKALHVLFERVSEEQLIEFIENKDYRVLLSTLSSFGR
DQEIVHHVLCCLHSLAVPCSNVEVLMSGNVRCYNIVVDAMKAFPTNEKIQEVSCSLLHRL
TLGNFFNILVLNEVHGFVEKAVWQYPENAALQISALSCLALLTETIFLNQDLEERSETQE
PSDEEDSEKLFWLEPCYKALTRHRKNKHVQEAACWALNNLLMYQNSLHQKIGDEDGQFPA
HREVMLSMLMHSSSKDVFQAAAHALSTLLEQNVYFRKILLAKGVYLNVLELMQRHAHAPE
VAESGCKMLSHLFEGSNTSLDTMAAVVPKILTVMKTHETSLSVQLEALRAVLHFVVPGAP
EESRDDAQCKLNVLKKQCFRTDIHKLVLAALNRFIGSPGIQKCGLKVISSVAHFPDALET
LSLHGAVDSVLHALQMYPDDQEIQCLGLHLMGCLITKKNFCIGTGHLLAKILVSSLQRFK
DVAEVQTTGLQTILSIFELSVSFSKLLVHYSFDLVIFHQMSSSIVERKDEQFLNLCCKCF
AKLAVDDDLKTTLLERACDQNNSIMVECLLLLGADANQVKGATSLIYQVCEKENSPKLVE
LLLNSGCREQDVRKALTVSIQKGDSQVISLLLRRLALDLANNSICLGGFCIGKIDPSWLG
PLFPDKSSNLRKQTNTGSVLARKVLRYQMKNTLQEGVASGSDGNFSEDALAKFGEWTFIP
DSSVDSVFGQSDDLDSEGSESSFLMKRKSNSVSVGELHRDPVLQRYSPNAQRHSSSLGPI
FDHEDLLRRKRKILSSDESLRSSKLQSHMRHSESSSSLASERESITSLDLSANELKDIDA
LSQKCCLSSHLEHLTKLELHQNALTGFPQQLCETLKCLTHLDLHSNKFTSFPSFLLKMTC
ITNLDASRNDIGPAVVLDPVLKCPSLKQLNLSYNQLSSIPENLAQAVEKLEQLLLEGNKI
SGICCPLSLKELKILNLSKNHIPSLPEDFLEACPKVESFSARNNFLTAMPALPSSITSLK
LSQNCFTCIPEVIFILPHLRSLDMSHNNIEHLPGPAHWKSLNLRELFFSNNQISTLDLSE
KPHVWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNVELRSFPNEMGKLSKIWDLPL
DGLHLNFDFKHVGCKAKDIIRFLQQRLKKAVPYNRMKLMLVGNTGSGKTTLLQQLMKTKK
SELGLQGATVGIDVRDWPIQIRGKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVY
DLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHSDVSDEKQRKACISKITKELLNKRGF
PTIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERK
AVPIEFPVINRKRLLQLVKEHQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVE
PKWLCKVMAQILTVKVEGCLKHPKGIISRRDVEKFLSKKKRFPKNYMAQYFKLLEKFQIA
LPIGEEYLLVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPFM
LSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVMDNRPESFLKITVPSCRKGCILLGQ
VVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDL
LINPDQPRLTVPISQIAPDLILADLPRNIMLDNDELEFEEAPEFLLGDGSFGSVYRAAYE
GEEVAVKIFNKHTSLRLLRQELVVLCHLHHPSLILLLAAGIRPRMLVMELASKGSLDRLL
QQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYG
IAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDIWTTGGRIVEGLRF
PNEFDEFAIQGKLPDPVKEYGCAPWPMVEKLIKKCLRENPQERPTSAQVFDILNSAELIC
LMRHILIPKNIIVECMVATNPNSKSATLWLGCGNTEKGQLSVFDLNTERYSYEEVTDSRI
LCLALVHLAAEKESWIVCGTQSGVLLVINVEDETKRHTLERMTDSVTCLYCNSFAKQSKQ
SNFLLVGTADGNLMIFEDKTVKCKGAAPLKTLHVGDVSTPLMCLSESLSSSERHITWGGC
GTKVFSFSSDFTIQKLIETRTNQLFSYAAFSDSNIIAVAVDTALYVAKKNSPVVEVWDKK
TEKLCELIDCVHFLKEVMVKTNKESKHKLSYSGRVKALCLQKNTALWIGTGGGHILLLDL
STRRVIRTIHNFCDSVRAMATAQLGNLKNVVLVLGYKRKTADGTEEQKEIQSCLFIWDIN
LPHEVQNLEKHIEVRTELADKMRRTAVD
NT seq
7647 nt
NT seq
+upstream
nt +downstream
nt
atgaactttcctcttagcactgctttcattgtgtcccataagtttggtctccgccgcacc
atggccagtggcgcctgtcagggctgcgatgaggaagaggaggaggaggaggctctgaag
aagttgatcgtcaggctgaacaatgtccaggaaggcaagcagatcgagacgctgctccag
ctcctggaggacttgctggtgttcacctactcagcccgcgcctctaagttatttgagggc
aaaaatttccacgtgcctctgttgattgtcctggattcctacatgagagttgccagtgtg
cagcaggtgggttggtcccttttgtgcaaattaatagaagtctgtccagggacattgcaa
agcttaataggaccacaggatgttggaaatgattgggaagtccttgggattcaccgactg
attcttaaaatgctgactgtccaccatgccaatgtaaacctgtcaacagttgggctaaaa
gccttagatctcctcctggagtcaggtaaaatcaccttgctgatactggatgaagaatgt
gatattttcttgttaatttttgatgccatgaacacgtactcagccaatggtgaagtccag
aaacttggatgcaaggctttacatgtgctttttgaaagagtttctgaggaacagctgatt
gagttcatcgagaacaaggattacagggtactgctgagcacactcagcagcttcggaagg
gaccaggagattgtgcatcacgtactctgctgcttgcattccctggcggttccttgcagc
aatgttgaagtcctcatgagtgggaatgtcaggtgttacaacattgtggtggacgccatg
aaagcatttcctaccaatgagaaaatccaagaagtgagctgctccttgctccatagactc
acattaggcaactttttcaacatcctggtgttgaatgaggtacatggctttgtggagaaa
gctgtctggcagtacccggagaacgcggccttacagatctctgcactcagctgtttagcg
ctcctcaccgagaccattttcttgaatcaagacttggaggaaagaagtgagactcaggag
cccagtgacgaggaggacagtgagaagcttttctggttggaaccctgctacaaagccctg
acgcgccatcggaagaacaaacacgtgcaggaggctgcatgctgggcactaaataatctc
ctcatgtaccagaacagtctacaccagaagattggagacgaagacggccagttccctgcg
cacagggaggtgatgctgtccatgctgatgcattcttcttccaaagatgtcttccaagca
gctgcgcatgcgctgtccactctcttggagcagaatgtttatttcaggaaaatcctgctg
gccaaaggagtatacctgaatgtcttggagttgatgcagaggcacgcccatgctccggag
gtggcagagagcggctgcaagatgctgagtcatctgtttgaaggaagtaacacctccctg
gatacgatggcggcagtggtccccaaaatactaacagtgatgaagacccacgagacatct
ctgtcagtgcagctggaggctctgcgagctgttttgcattttgtagtgccaggagcacca
gaggaatccagggatgatgctcagtgcaaactaaatgtgctcaaaaaacagtgtttccga
actgatatccacaagctggttctagccgctctgaaccggttcattgggagtcccgggatt
cagaaatgtggactgaaagtaatctcttctgtggcacattttcctgatgccttggagacg
ctgtccctgcatggcgccgttgactcagttcttcacgctttgcagatgtatccagacgac
caagaaattcagtgtctgggcttacatcttatgggatgcttgattacaaagaagaatttc
tgcatagggacagggcatctcctggcaaaaattctggtttccagtttacagcgatttaaa
gatgttgctgaagtgcagactacaggattacagacaatcttgtcaatatttgaactgtca
gtatccttctctaagcttctggtgcactattcatttgatttggtaatatttcatcagatg
tcttccagcattgtggaacggaaggatgaacagtttctcaacctatgttgcaaatgcttt
gcaaaactggccgtggatgatgacttgaaaaccacgttgctagagagagcctgcgatcaa
aataacagcattatggtggaatgtttgcttttgttgggagctgatgccaatcaagtgaag
ggggcaacttctttaatttatcaggtatgtgagaaagagaacagtcccaaattggtggaa
ctgttgcttaacagtggatgccgtgagcaagatgtacggaaagcactgacagtgagcatc
cagaagggcgacagccaggtcatcagcttgctcctgagaaggcttgctctggacctggcc
aacaacagcatttgccttggaggattttgcataggaaaaattgatccttcttggcttggt
cctttatttccagataagtcatctaatttaaggaaacaaacaaacacaggctctgtccta
gcaagaaaagtgctccggtatcagatgaaaaatactctgcaagaaggagtggcctcaggc
agtgatggcaacttttctgaagacgcactggcgaaatttggtgaatggaccttcattccc
gattcttctgtggacagtgtgtttggccaaagtgatgatctggatagtgaaggcagtgag
agctcctttctcatgaaaaggaagtcgaattcggttagtgtaggagaacttcacagagat
ccggttttgcagcgttactcaccaaatgcacagaggcattccagttcattgggtcccatt
tttgatcatgaggacttgctgagacgaaaaagaaaaatactgtcttcagatgagtctctc
aggtcatcaaagcttcagtctcacatgaggcactcagagagctcttcttccctggcttct
gagagagagagcatcacatccttggacctttctgccaatgaactgaaagatatcgatgcc
ctgagccagaagtgttgcctcagtagccacctggaacacctcaccaagctggagcttcac
cagaatgcactcacgggcttccctcagcagctgtgtgagactctaaagtgtttgacacat
ttggatttgcacagtaacaaattcacatcatttccctccttcctgctgaaaatgacgtgt
atcaccaacctagatgcctctcgcaatgacattggaccagcagtagttttagaccccgtg
ctgaagtgtccaagcctcaaacagcttaacctctcatacaaccagctctcttccatccca
gagaaccttgcccaggcggtggagaaactggagcagctcctattggaaggaaataaaata
tctgggatttgttgtcccttgagcctgaaggaactgaagattttaaatcttagtaaaaac
cacattccatccctacctgaagactttcttgaggcttgtccaaaagtggagagtttcagc
gctcggaataattttcttactgcaatgcctgccttaccttcttccataacaagcctaaaa
ttatctcaaaactgtttcacatgcattccagaagtgattttcattcttccacacttgcgg
tccttggatatgagccacaacaacattgaacatctgccagggcctgcacattggaagtct
ctgaacttgcgggaactcttctttagcaataatcagatcagcaccttggacttgagtgaa
aagccgcatgtgtggtcgagagtagagaaactgcatctctctcataataaactgaaagag
atccctcctgaaattggatgtcttgaaaatctgacatctcttgatgtcagttacaacgtg
gaactgaggtcttttccaaatgaaatggggaaattaagcaaaatatgggatcttcctttg
gatggactgcatctgaatttcgactttaaacatgtaggatgcaaagccaaagacatcata
aggtttcttcaacaacgactgaaaaaggctgtgccctacaaccgaatgaagctcatgctt
gtgggaaacactgggagtggcaagaccactttactgcagcagctcatgaaaacgaagaaa
tcggaactcggccttcagggtgctacggtcggcattgacgtgagagactggcctatccag
atacgaggcaaaaggaaacgggaccttgttctgaacgtgtgggactttgcaggtcgtgag
gaattctacagcacccacccccacttcatgacccagagagctctgtacctcgctgtctat
gatctcagcaagggacaggcagaggtggacgccatgaagccctggctcttcaacatcaag
gctcgtgcctcttcatccccagtgattctggtgggcacacattcggatgtttctgacgag
aagcagcgcaaagcctgcataagcaaaattaccaaggaacttctaaataagagaggattc
cccaccatccgggactaccacttcgtgaatgccaccgaggagtcggacgccctggcaaag
cttcggaagaccatcatcaacgagagtctgaatttcaagatccgagatcagcctgtagtc
gggcagctaattccagattgctatgtagaactggagaaaatcattttatcagagcgtaaa
gctgtgccaattgagtttcctgtaattaaccggaaacgtttattacaactagtgaaagaa
catcagctgcagctggatgagaatgagctcccacatgctgttcatttcctaaatgagtca
ggagtccttctgcattttcaagaccccgctctgcagttaagtgacctgtatttcgtggaa
ccaaaatggctttgtaaagtcatggcacagattttgacggtgaaggtggaaggctgtctg
aaacatcctaagggcatcatttcacggagagatgtggaaaaattcctttcaaagaaaaag
cgattcccgaagaactacatggcacagtactttaaactgttagaaaaatttcagattgcc
ttgccaatcggagaagaatatctgctggttccaagcagcctatctgaccacaggcctgtg
atagagctcccgcactgtgagaactctgagatcatcatccggctctacgaaatgccatac
tttccaatgggattttggtcaagactgattaatcgattacttgaaatctcacctttcatg
ctttctggaagagagagagcgctacgtccgaacagaatgtactggcgacaaggcatctac
ttgaactggtctccagaagcgtattgtctggtaggatccgaagtcatggacaatcgcccg
gagagtttcttaaaaattacagttccgtcttgtagaaaaggttgtattctcttgggccaa
gttgtggatcacattgactcactcatggaagaatggtttcctgggttgctggagattgac
atttgtggggaaggggaaactctgctgaaaaaatgggcgttgtacagttttaacgatggt
gaagaacatcagaagatcttactggacgacttgatgaagaaagcagaagaaggagacctg
ctaataaatccagatcaaccacggctcactgttccaatatctcagattgctcctgacttg
attttggccgacctgcctagaaatattatgttggacaatgatgagttggaatttgaagaa
gcacctgagtttctcttaggcgatggaagttttggatcagtttatcgagccgcctacgaa
ggggaggaagtggccgtgaagatctttaataaacacacgtcacttaggctgttaagacaa
gagttggtggtactttgccacctccaccaccccagcttgatactgttgctggcggccggg
atccgtcctcggatgttggtcatggagttggcctccaagggttccttggaccgcctgctg
cagcaggacaaggccagcctcacaagaaccctccaacacaggattgcactgcatgtggct
gacggcctgaggtacctccactcagccatgattatttaccgtgatctgaaaccccacaat
gtgctgctttttaccctctatcccaacgctgccatcattgcgaagattgcggactacggg
attgcacagtactgctgtagaatgggaataaagacatcagaaggcaccccagggttccgg
gcacctgaagttgccagaggaaatgtcatttataaccagcaggctgatgtttattcattt
ggcttactgctgtatgatatttggacaactggcggtagaattgtagagggtttgaggttt
ccaaatgagtttgatgaatttgcaatacaagggaaattaccagatccagttaaagaatat
ggctgtgccccatggcctatggttgagaagttaattaaaaagtgtttgagagagaatcct
caagaaaggcccacttctgcacaggtctttgacattttgaattcggctgaattaatttgt
ctcatgcggcacattttaatacctaagaacattattgttgaatgcatggttgctacaaat
cccaatagcaagagcgctactctttggttgggctgtgggaacactgaaaagggacagctc
tctgtctttgacttaaacacggaaagatacagctatgaggaagttactgatagtagaata
ctgtgcttggctttggtgcatcttgctgctgagaaagagagctggattgtgtgtgggaca
cagtctggggttctgctggtcatcaacgtggaagacgagacaaagaggcacaccctggaa
aggatgactgactctgtcacttgtttgtactgcaattcctttgccaagcagagcaagcaa
agtaattttcttttggtgggaaccgctgatggtaatttaatgatatttgaagataagacc
gttaagtgtaaaggagctgctcccttgaagacactgcacgtaggcgatgtcagtacaccc
ctgatgtgcttgagtgagtccctgagttcatccgaaagacacatcacatggggagggtgt
ggcacaaaggtcttctccttttccagcgatttcaccattcagaaactcatcgagacgaga
accaaccagctgttttcctacgcagccttcagtgattccaacatcatagcagtggcagtg
gacacggccctctatgttgccaagaaaaacagccccgtggtcgaggtgtgggacaagaag
actgaaaagctctgtgaattaatagactgtgtgcacttcttaaaggaggtgatggtaaaa
acaaacaaggagtccaaacacaagctgtcctactccgggagggtgaaagctctctgcctg
cagaagaacacggctctctggatcggaactgggggaggccacatcttactcctggatctc
tctactcgccgagtcatacgcaccattcataacttctgtgattctgtgagagccatggcc
acagcacaattaggcaaccttaaaaacgtcgtgctggttttggggtacaagcggaagact
gcagacggtaccgaagaacaaaaagagatacaatcctgcttgtttatttgggacattaat
cttccacacgaagtacaaaatttagaaaagcacattgaagtaaggacagaattagctgat
aaaatgcggagaacggctgttgactag
DBGET
integrated database retrieval system
