KEGG   Meriones unguiculatus (Mongolian gerbil): 110548425
Entry
110548425         CDS       T05884                                 
Symbol
Cacna1s
Name
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun04010  MAPK signaling pathway
mun04020  Calcium signaling pathway
mun04022  cGMP-PKG signaling pathway
mun04024  cAMP signaling pathway
mun04260  Cardiac muscle contraction
mun04261  Adrenergic signaling in cardiomyocytes
mun04270  Vascular smooth muscle contraction
mun04723  Retrograde endocannabinoid signaling
mun04725  Cholinergic synapse
mun04726  Serotonergic synapse
mun04727  GABAergic synapse
mun04911  Insulin secretion
mun04912  GnRH signaling pathway
mun04921  Oxytocin signaling pathway
mun04924  Renin secretion
mun04925  Aldosterone synthesis and secretion
mun04927  Cortisol synthesis and secretion
mun04929  GnRH secretion
mun04934  Cushing syndrome
mun04935  Growth hormone synthesis, secretion and action
mun05010  Alzheimer disease
mun05020  Prion disease
mun05022  Pathways of neurodegeneration - multiple diseases
mun05207  Chemical carcinogenesis - receptor activation
mun05410  Hypertrophic cardiomyopathy
mun05412  Arrhythmogenic right ventricular cardiomyopathy
mun05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110548425 (Cacna1s)
   04020 Calcium signaling pathway
    110548425 (Cacna1s)
   04024 cAMP signaling pathway
    110548425 (Cacna1s)
   04022 cGMP-PKG signaling pathway
    110548425 (Cacna1s)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    110548425 (Cacna1s)
   04929 GnRH secretion
    110548425 (Cacna1s)
   04912 GnRH signaling pathway
    110548425 (Cacna1s)
   04921 Oxytocin signaling pathway
    110548425 (Cacna1s)
   04935 Growth hormone synthesis, secretion and action
    110548425 (Cacna1s)
   04924 Renin secretion
    110548425 (Cacna1s)
   04925 Aldosterone synthesis and secretion
    110548425 (Cacna1s)
   04927 Cortisol synthesis and secretion
    110548425 (Cacna1s)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    110548425 (Cacna1s)
   04261 Adrenergic signaling in cardiomyocytes
    110548425 (Cacna1s)
   04270 Vascular smooth muscle contraction
    110548425 (Cacna1s)
  09156 Nervous system
   04727 GABAergic synapse
    110548425 (Cacna1s)
   04725 Cholinergic synapse
    110548425 (Cacna1s)
   04726 Serotonergic synapse
    110548425 (Cacna1s)
   04723 Retrograde endocannabinoid signaling
    110548425 (Cacna1s)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    110548425 (Cacna1s)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110548425 (Cacna1s)
   05020 Prion disease
    110548425 (Cacna1s)
   05022 Pathways of neurodegeneration - multiple diseases
    110548425 (Cacna1s)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    110548425 (Cacna1s)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    110548425 (Cacna1s)
   05414 Dilated cardiomyopathy
    110548425 (Cacna1s)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110548425 (Cacna1s)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mun04040]
    110548425 (Cacna1s)
Ion channels [BR:mun04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   110548425 (Cacna1s)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 110548425
NCBI-ProteinID: XP_021492333
LinkDB
Position
11:57560676..57626741
AA seq 1870 aa
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRI
FRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWTSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSIMAKKLEQKSKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFT
AVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFIFACIGVQLFKGKFYSCNDL
SKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDANEEDTGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKQCDPESDYLPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFGEIEMEELESPVFLEDFPHNPGTHPLARANTNNANANVACGNSSHRNSPV
FSSICYEREFPEEADTPAREGPFRQPCRVSGPQSKSGVEKLKGQVAQRMSGGQVPPSPCQ
AEPPVQEERMGTLPRSLETPHNRNFEERVPRNAAHRCTAPATAVLIQEALVRGGLDSLAA
DANFIMATGQALADACQMEPEEVEVAATELLKQESPEGRAMXLGGLSLRPSLGSLRQHRG
SQKFLIPPRC
NT seq 5613 nt   +upstreamnt  +downstreamnt
atggagccgtcctcacctcaggatgagggcctgaggaagaaacagcccaagaaacctgtt
cctgagattctgccgaggccaccccgggccttgttctgcttgactctccagaaccctcta
aggaaggcctgcatcagcattgtggagtggaaaccctttgagaccatcatcttgctcacc
atttttgccaactgtgtggccctggcagtgtacctgcccatgcctgaagatgacaacaac
actctgaaccttggcctggagaagctggagtacttcttcctcatcgtcttctccatcgag
gctgccatgaagattatagcctacggcttcctgttccaccaggacgcttacctgcgcagc
ggctggaacgtgctggacttcatcattgtctttctaggtgtctttactgcgattctggag
caagttaacattattcagacgaacacggcccccatgagcagcaaaggagctggcttggat
gtgaaggccctgcgagctttccgcgtgctcagaccgctgcggctggtgtcaggggtgccc
agccttcaggtagtcctcaactccatcttcaaggccatgctccccctgttccacatagcc
ctgcttgtcctctttatggtcatcatctacgccatcattgggttggagctcttcaagggc
aagatgcacaagacttgctacttcattgggacggacattgtggccacagtggagaatgag
aagccatcaccctgtgctagaacgggctctgggcgcccctgcaccatcaacggcagtgag
tgccgaggaggctggccagggcccaaccacggcatcacccactttgacaacttcggcttc
tccatgctcaccgtgtaccaatgcatctccatggaggggtggacagatgtcctctactgg
gtcaacgatgccatcgggaatgagtggccttggatctattttgtcacccttattctgctg
ggttccttcttcatcctcaacctggtgctgggtgtcctgagcggagaattcaccaaggag
cgagagaaagccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggaccttcgaggctacatgagctggatcacccagggcgaggtcatggacgtggaggac
ctgagagaaggcaagctgtctctggatgaagggggctcagatacagagagcttgtatgaa
atcgagggcttgaacaaaatcatccagttcattcggcactggaggcagtggaatcgcatc
ttccgctggaagtgtcatgacctcgtgaaatccaaggtcttctattggctggtgatcctg
attgttgccctcaacaccctgtctattgcctcagagcaccataaccagccactctggctg
acccatttgcaagatgttgccaaccgcgtgctgctggccctcttcaccatcgaaatgctg
atgaagatgtatggcctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagattctgctggtggagtcgggagccatgaca
cccctgggcatctcagtgctccgctgcatccgccttcttaggctcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcctcactgctcaactccatccgctccatcgcc
tccctgctgctgctactctttcttttcatcgtcatctttgccctgctgggcatgcagctc
tttggaggtagatatgactttgaagacacggaagtacggcgcagcaactttgacaacttc
ccccaggccctcatcagtgtattccaggtcctgacgggtgaagactggacctctgtgatg
tacaatgggatcatggcctacggaggcccaacctaccctggtgtgctcgtgtgcatctac
ttcatcatcctttttgtttgtggcaactacatcctgctcaacgtcttcctggctatcgct
gtggacaacctggcagaggcagagagtctgacttctgcccagaaggccaaggccgaggag
agaaagcgcaggaagatgtctaagggtctcccagacaagtcagaagaagagaagtccata
atggctaagaagctggagcagaagtccaagggtgaaggcatccctaccaccgccaagctg
aaaattgatgagtttgaatctaacgtgaatgaggtgaaagacccgtacccttcagcagac
ttcccaggggacgatgaagaagatgagcctgaaatcccagtgagcccccgaccacgcccc
ctagctgagttgcagctgaaagagaaagcagtgcccattccagaggccagctccttcttc
atcttcagccccaccaataagatccgtgtcctatgtcaccgcattgtcaatgccacctgg
ttcaccaactttatcctgctcttcatcctgctcagtagtgctgcactggccgctgaggat
cccatccgggccgactccatgaggaatcagatccttgagtattttgattatgtgttcact
gctgttttcaccgtggaaatcgtccttaagatgaccacctacggagccttcctgcacaaa
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggctgtgtcactc
atctccatgggcctcgagtccagcgccatctctgtggtgaagatcttgagggttctgagg
gtgctacggccactccgagccataaacagagccaaagggttgaagcacgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaacatcgtgctggtcaccaccctcctgcagttc
atatttgcctgcatcggagtccagcttttcaagggaaagttctacagctgcaatgactta
tccaagatgactgaagaggagtgcaggggctactactacatatacaaggatggagacccc
acgcagatagagctgcgtccccgccagtggatacacaatgacttccactttgacaatgtg
ctctcagctatgatgtcactcttcacagtctccacctttgagggttggcctcagctgctg
tacaaggccattgacgcaaatgaggaggacacaggtcccatctacaataaccgagtggag
atggctattttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggctttgtcattgtcaccttccaggagcagggagagactgagtataagaactgtgag
ctggacaagaaccagcgccaatgtgtacagtatgccctgaaggcccgcccactgaggtgt
tacatccccaaaaacccataccagtatcaggtatggtacgtcgtcacttcctcctacttt
gaatacctgatgtttgctctcatcatgctcaacactatctgcctaggcatgcagcattac
aaccagtcagaacagatgaaccacatctcagacattctcaatgtggccttcaccatcatc
ttcaccctggagatgatcctcaagctcatagcattcaagcccaggggctattttggagat
ccctggaatgtgtttgacttcctaattgtcatcggcagcatcattgacgtcatcctcagt
gagatcgatactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagatgagagcgcccgcatctccagtgccttcttccgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggcgtgcgcaccttgttgtggacgttc
atcaagtccttccaggccctgccatatgtggctttgctcattgtcatgctcttcttcatc
tacgcggtcattggcatgcagatgttcgggaagatcgccttggtggacgggacgcaaata
aaccgcaacaacaactttcagactttccctcaagctgtgctgctgctcttcaggtgtgcc
acaggggaagcctggcaagagatcctgctggcctgcagctatggaaagcagtgtgaccca
gagtctgactacctgcccggggaggagcacacgtgcggcaccaactttgcttactactac
ttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatc
atggacaactttgactacctcacaagggactggtccattctgggccctcaccacctggat
gagttcaaggccatctgggctgagtatgaccccgaggctaagggcagaatcaagcacctg
gatgtggtgaccctgctgaggaggatccagccccctctgggctttgggaagttctgccca
cacagggtggcatgtaagaggctggtgggcatgaacatgcccctgaacagcgatggcacg
gtcaccttcaatgccacactctttgccctggtgcgcacagccctcaagatcaagacggaa
ggcaactttgaacaagctaatgaggagctgagagccatcatcaagaagatctggaagaga
accagcatgaaactcctggaccaagtcattcctcctataggagatgatgaggtgacggtg
gggaagttctacgccacattcctcatccaggagcacttccggaagttcatgaagcgccag
gaggaatactatgggtacagacccaaaaaggacacagttcagatacaggctggattacgg
accatagaggaagaggcagctcctgagatccaccgtgccatctcaggagacctgacggca
gaggaggaactggagagagccatggtggaggctgccatggaggagggaatattccggagg
actggaggactgtttggtcaagtggacaacttcctggaaaggaccaactctctgccccct
gtcatggccaaccaaagacccctccaatttggtgagatagagatggaagaactggagtca
cccgtcttcttggaggacttccctcataacccgggcacccacccgcttgctcgtgccaat
accaacaacgccaatgccaatgttgcctgtggcaacagcagccatagaaacagcccagta
ttttccagcatctgctatgaaagggagttcccagaagaggcagacacgcctgccagagaa
ggacccttcaggcagccctgcagggtttctggacctcagagcaaatctggtgtggagaaa
ctgaaaggacaggtggcccagagaatgtctggaggccaggtgcctccttccccatgccag
gcagagcctcctgtgcaggaagagagaatgggcaccttgccaagatctctggaaacaccc
cacaacaggaactttgaggagagagttccaaggaacgcagctcacaggtgcacagctcca
gctactgcagtgctgatccaggaggctctggttcgaggagggctagactccttagcagca
gatgctaatttcatcatggcaactggccaggccctggcagatgcctgccagatggaacca
gaggaagtagaggtggcagcaacagagctactgaagcaagaatctccagagggcagggcc
atgntcctgggaggcttgagcctcaggccctccctgggcagcctaagacagcaccggggc
tcccaaaagttccttattcctcccaggtgttag

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