Meriones unguiculatus (Mongolian gerbil): 110550263
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Entry
110550263 CDS
T05884
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00562
Inositol phosphate metabolism
mun01100
Metabolic pathways
mun01521
EGFR tyrosine kinase inhibitor resistance
mun04012
ErbB signaling pathway
mun04014
Ras signaling pathway
mun04020
Calcium signaling pathway
mun04062
Chemokine signaling pathway
mun04064
NF-kappa B signaling pathway
mun04066
HIF-1 signaling pathway
mun04070
Phosphatidylinositol signaling system
mun04072
Phospholipase D signaling pathway
mun04360
Axon guidance
mun04370
VEGF signaling pathway
mun04380
Osteoclast differentiation
mun04611
Platelet activation
mun04613
Neutrophil extracellular trap formation
mun04625
C-type lectin receptor signaling pathway
mun04650
Natural killer cell mediated cytotoxicity
mun04662
B cell receptor signaling pathway
mun04664
Fc epsilon RI signaling pathway
mun04666
Fc gamma R-mediated phagocytosis
mun04670
Leukocyte transendothelial migration
mun04722
Neurotrophin signaling pathway
mun04750
Inflammatory mediator regulation of TRP channels
mun04919
Thyroid hormone signaling pathway
mun04933
AGE-RAGE signaling pathway in diabetic complications
mun04935
Growth hormone synthesis, secretion and action
mun05167
Kaposi sarcoma-associated herpesvirus infection
mun05169
Epstein-Barr virus infection
mun05170
Human immunodeficiency virus 1 infection
mun05171
Coronavirus disease - COVID-19
mun05200
Pathways in cancer
mun05205
Proteoglycans in cancer
mun05206
MicroRNAs in cancer
mun05214
Glioma
mun05223
Non-small cell lung cancer
mun05225
Hepatocellular carcinoma
Module
mun_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
110550263 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
110550263 (Plcg2)
04014 Ras signaling pathway
110550263 (Plcg2)
04370 VEGF signaling pathway
110550263 (Plcg2)
04064 NF-kappa B signaling pathway
110550263 (Plcg2)
04066 HIF-1 signaling pathway
110550263 (Plcg2)
04020 Calcium signaling pathway
110550263 (Plcg2)
04070 Phosphatidylinositol signaling system
110550263 (Plcg2)
04072 Phospholipase D signaling pathway
110550263 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110550263 (Plcg2)
04613 Neutrophil extracellular trap formation
110550263 (Plcg2)
04625 C-type lectin receptor signaling pathway
110550263 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
110550263 (Plcg2)
04662 B cell receptor signaling pathway
110550263 (Plcg2)
04664 Fc epsilon RI signaling pathway
110550263 (Plcg2)
04666 Fc gamma R-mediated phagocytosis
110550263 (Plcg2)
04670 Leukocyte transendothelial migration
110550263 (Plcg2)
04062 Chemokine signaling pathway
110550263 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
110550263 (Plcg2)
04919 Thyroid hormone signaling pathway
110550263 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
110550263 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
110550263 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
110550263 (Plcg2)
04380 Osteoclast differentiation
110550263 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110550263 (Plcg2)
05206 MicroRNAs in cancer
110550263 (Plcg2)
05205 Proteoglycans in cancer
110550263 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
110550263 (Plcg2)
05214 Glioma
110550263 (Plcg2)
05223 Non-small cell lung cancer
110550263 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
110550263 (Plcg2)
05171 Coronavirus disease - COVID-19
110550263 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
110550263 (Plcg2)
05169 Epstein-Barr virus infection
110550263 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
110550263 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110550263 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mun04131
]
110550263 (Plcg2)
Enzymes [BR:
mun01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
110550263 (Plcg2)
Membrane trafficking [BR:
mun04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
110550263 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
110550263 (Plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
110550263
NCBI-ProteinID:
XP_021495709
LinkDB
All DBs
Position
10:complement(10529216..10655634)
Genome browser
AA seq
1265 aa
AA seq
DB search
MSTMINVDSLPEYEKSQLKRALELGTVMTVFSARKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRHKGDCCFTIFYGTQFVLSTLSLATDSKEDAA
KWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKAILPIVNFKVSNV
KFLKDRVVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLQDFQRFLLHEQQEAWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKCDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRAGCRCIELDC
WDGPDGKPVIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRYMAKV
FKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHRTQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEEPVQDTPPTELHFGEKWFHKKVERR
TSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYY
LTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDML
MRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQII
EDNPLGPLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKPGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVE
TKADSIVRQKPLELLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEHDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccatgatcaacgtggacagccttccggaatatgagaagagtcagctcaagaga
gccctggagctagggacggtgatgaccgtgttcagcgcccgcaagtccaccccggagcgg
aggacggtccaggtgatcatggagactcgccaggtggcgtggagcaagactgcagacaag
atcgagggcttcttggacatcatggaaataaaggaaatccgtccagggaagaactccaag
gactttgagcgagccaaggctgtccgccacaagggagattgctgcttcaccatcttctac
ggcacccagttcgtcctcagcacactcagtttggcaactgactccaaggaggacgcagcg
aagtggctctctggcctgaagatcctgcaccaggaagcgatgagtgcgtccacacccacc
atgattgagagttggctgaggaagcagatttactcagtagatcaaacccgaagaaacagc
atcagcctccgggagctgaaggccatcttgcccatcgtcaacttcaaagtgagcaatgtc
aagttcctcaaggacagggtggtggaaattggtgcacagaaggatgagctcagttttgaa
cagttccatctcttctataaaaaactcatgtttgaacagcagaaatcgatactcgatgaa
ttcaaaaaagactcctccgtgtttatcctagggaacacagaccgccccgatgcctctgct
gtctacctgcaggacttccagaggtttctcttacatgaacagcaggaggcctgggctcag
gatctgaacaaagtgcgggagcggatgaccaagtttatcgacgacacgatgagggaaact
gcggagcccttcttgtttgtggacgagttcctcacgtacctgttctcccgagagaacagc
atctgggatgagaagtgtgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcttcttcccacaacacgtacctcaccggggaccagctgcgtagcgagtcc
tccccggaagcgtatatccgctgcctacgagctggctgtcgctgcatcgagttggactgc
tgggacgggcctgacgggaagcccgtaatctaccatggctggacacggaccaccaagatc
aagtttgacgacgttgttcaggccatccgagatcacgcctttgttacctccagcttcccc
gtgatcttgtctatcgaggagcactgcagtgtggagcagcagcgttacatggccaaggtg
ttcaaggaggtgctgggagacctgctgctgacgaagcccacggaggccagcgctgaccag
ctgccctcgcccagccagctccgagagaagatcattatcaagcataagaagttgggtccc
cgaggtgatgtcgatgtcaatgtggaagacaagaaagatgagcacaggacccagggcgag
ctgtacatgtgggactccatcgaccagaaatggactcgccactactgtgccattgctgac
gccaagctgtccttcagcgatgacattgagcagacggtggaggaggagccggtccaggac
actccccccacggagctgcattttggggagaaatggttccataagaaggtagagaggaga
accagtgcggagaagctgctgcaggaatactgcgccgagacgggggccaaggacggaacc
ttcctggtgcgggagagcgagaccttccccaatgactacacgctctccttctggcgttct
ggccgggtgcagcactgccgaatccgctccaccatggagggtggggtcatgaagtactac
ctgaccgacaacctcaccttcaacagcatctacgccctcatccagcactaccgcgaggca
cacctgcgctgtgccgagttcgagctgcggctcacagacccagtgcccaaccccaaccca
cacgagtctaagccgtggtactatgataggctgagcaggggggaagcagaggacatgctg
atgcggatcccccgagacggagccttcctcatccggaagcgggaggggaccgactcctat
gccatcaccttcagggccaggggcaaggtgaaacactgtcgcatcaaccgggatggccgg
cactttgtactggggacctctgcctactttgagagcctggtggagcttgtcagctactac
gagaagcacgcgctctaccgcaagatgaggctgcgctaccccgtgacccccgagctcctg
gagcgatataatatggaaagagacatcaactctctctatgacgtcagcaggatgtacgtg
gacccgagtgaaatcaacccttccatgcctcagaggactgtgaaagcgctctatgactac
aaagccaagcgcagtgacgagttgaccttctgccgcggtgccctcatccacaacgtctcc
aaggagcctgggggatggtggaaaggggactacgggacccggatccagcagtactttccg
tccaactacgttgaggatatctcagcaggcgacgccgaggagatggaaaagcagatcatt
gaagacaaccccctggggcctctttgcagaggcatcttggaccttaacacctacaatgtt
gtgaaggccccccaggggaaaaaccagaaagcgttcgtcttcatcctggagcctaagaag
ccaggggatcctcccgtggagtttgccaccgaccgcgtggaggagctctttgagtggttt
cagagcatcagagagatcacttggaagattgacaccaaggagaacaacatgaagtactgg
gagaggaaccagtccatcgccattgagctgtccgacttggttgtgtactgcaagccgact
agcaaaaccaaggaccatttggagaaccctgacttcagggaaatccgctcctttgtggag
acaaaggcagacagcattgtcaggcagaagccccttgagctactgaggtacaaccagaag
ggcctgacacgtgtctacccgaagggacagagggtcgactcctcaaactacgaccccttc
cgcctgtggctgtgtggctcccagatggtggcgctcaacttccaaactgcagacaagtac
atgcagatgaaccacgcgttgttttcactcaacgggaggacgggctacgtcctgcagccc
gagagcatgcggtctgagaagtatgacccgatgccaccagagtcccagaggaagatcctc
atgacactcacggtcaaggttctgggtgcacgccacctccccaaactagggcggagtatt
gcctgtccttttgtggaggtggaaatctgcggggctgagcatgacagcaacaagttcaag
acaacggttgtgaatgacaatggcctcagccctgtctgggctccaactcaggagaaggtg
acgtttgaaatttatgacccaaacctcgcattcctgcgctttgtggtctatgaggaagat
atgttcagtgaccccaacttcctggctcacgccacgtaccccatcaaaggcatcaaatca
gggtttagatcggtccctctgaagaatggctacagcgaagacatcgagctggcttccctt
ctggttttctgtgagatgcggccagtcctggagagtgaagaggaactctactcctcctgt
cgtcagctgcggaggcgtcaagaggagctcaacaaccagctcttcctgtacgacacgcac
cagaacctgcgcggagccaaccgtgatgccctggtcaaggagttcaacgttaacgagaac
cagctgcagctgtaccaggagaagtgcaaccggaggttgagagagaagagagtcagcaac
agcaggttctactcctag
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integrated database retrieval system
