Meriones unguiculatus (Mongolian gerbil): 110552278
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Entry
110552278 CDS
T05884
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00270
Cysteine and methionine metabolism
mun00480
Glutathione metabolism
mun01100
Metabolic pathways
mun01240
Biosynthesis of cofactors
mun04216
Ferroptosis
Module
mun_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
110552278 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
110552278 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
110552278 (Gclc)
Enzymes [BR:
mun01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
110552278 (Gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
110552278
NCBI-ProteinID:
XP_021499120
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Position
6:complement(11149150..11191825)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKVQLFLNGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEATSVLGENQALCTITSFPRLGCPGFTLPEHKPNPEEGSASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVETFPEDEEASKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNRFRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIHEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKINLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAVVDGCSKAQTSSEPAAEEYALMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVVTDEINYS
LILKCNQIANELCECPELLGSGFRKAKYSGGRSDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgctgagctgggaggagacccagcgccacgccgac
cacgtgcggcggcacggcatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggtgacgaggtggaatacatgttggtgtcctttgatcat
gaaaatagaaaagtccagttgttcctgaatggagaagacgttcttgaaactctgcaggag
aagggggaaagaacaaaccccaaccacccaaccctctggagaccggagtatgggagctac
atgattgaaggaacacctggccagccttatggaggaacaatgtcggagttcaacacagtg
gaggacaacatgaggaaacgccggcaggaggctacctctgtattgggagaaaaccaggct
ctttgcacgataacttcatttcccagactaggctgccctggattcaccctgccggagcac
aaacccaacccagaggaaggaagtgcatctaagtccctcttctttccagacgaagccata
aacaagcacccccgttttggcaccctaacaagaaacatccggcataggagaggagagaag
gttgtcatcaatgtgccaatattcaaggacaagaatacaccatctccatttgtagaaaca
tttcctgaagatgaggaggcatcaaaggcttctaagccagaccatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacattccaagcctgcagcatatct
gaggccagatacctttatgaccagctggctactatctgcccaattgttatggctttgagt
gctgcatctccattttaccgaggctatgtgtcagacattgattgtcgctggggagtcatt
tctgcatctgttgatgatagaacacgggaggagagaggactggagcctctgaagaacaat
cgctttagaattagtaaatctcggtatgattcaatagatagctacctctctaagtgtggt
gagaaatacaatgacatcgacctgaccattgataaagaaatccacgagcagctcttacag
gaaggtattgaccatcttctggcacagcacgttgctcatctttttattagagacccgctc
accctttttgaagagaaaataaacctggatgatgccaatgagtcggaccattttgagaat
atccaatccacaaactggcagacaatgaggtttaagccccctcctccaaactcagatatt
ggatggagagtagagttccgacccatggaggtgcagttaacagactttgagaactctgcc
tatgtggtatttgtggttctgctcaccagggtgattctctcatacaaactggatttcctc
attccactgtccaaggttgatgaaaacatgaaagtggcacagaagcgagatgctgtcttg
caggggatgttttatttcaggaaagacatttgcaaaggtggcaacgctgtggtggatggg
tgtagtaaggcgcagaccagctctgagccagcagcagaggagtacgccctcatgagcatc
gacaccatcatcaacgggaaggaaggggtgtttcctggactcatccccatcctgaactcc
tatcttgaaaacatggaagtagatgtggacaccagatgcagtattctgaactacctgaag
ctgattaagaagagagcgtcgggagaactaatgactgttgccaggtggatgagagagttt
atcgcaaaccatcctgactacaagcaagacagtgtagtaactgatgagattaactatagc
ctcattttgaagtgtaaccaaattgcaaatgaattatgtgaatgtccagagttactcgga
tcaggatttagaaaagcgaagtacagtggaggcagaagcgacccttcgaactag
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