Meriones unguiculatus (Mongolian gerbil): 110555618
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Entry
110555618 CDS
T05884
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00310
Lysine degradation
mun01100
Metabolic pathways
mun05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
110555618 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
110555618 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mun03036
]
110555618 (Dot1l)
Enzymes [BR:
mun01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
110555618 (Dot1l)
Chromosome and associated proteins [BR:
mun03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
110555618 (Dot1l)
HMT complexes
Dot1-containing complex
110555618 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
VPS13_M
Motif
Other DBs
NCBI-GeneID:
110555618
NCBI-ProteinID:
XP_021504591
LinkDB
All DBs
Position
17:17337673..17379124
Genome browser
AA seq
1736 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATSCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNAATPTKVP
EGKAGTTEAPADSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAS
AERKSKKSQSALDLLRSPPPAPPSASPQDAYRPPHSPFYHLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLDYTKTPQYKANLQKLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKGALGRDLEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAAGYEL
CSAASRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKSSGLALPDYTRLSPAKIVLR
RHMNQDHSGASKAAASEPHPRAEHAKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSSTLEKQIGASAHGAGASAAGSKSLALGPTGFYTGSVAISGALASSPAPLAP
GMESAVFEESSGPGSLFASMGSRSTPPQHPPLLPQSRNSGPASPGHQLAASPRLSVTTQG
PLPDTGKGELPSDPAFSDPESEAKRRIVFSIAAGSSSKQSPSTRHSPLTSGTRGDCVQNH
GQDSRKRSRRKRASAGTPSLSTGVSPKRRALPAVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPENSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSTR
IERKIATISLESKSPPKTLENGGGLAGRKSAPSSEPINSSKWKSTFSPISDLSLAKAVDS
PLQAGSALSHSPLFSFRPALEEPAAEAKLPTHPRKSFAGSLAPAEGPSPGANPPNGLAFS
GGLAADLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGG
LKGEGNAGKESGEALPPCGPADKATLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGL
LGGPGLVTVASSAGSATPTAQAPRPFLSTFTPGPQFTLGPMSLQANLGSVAGSSVLQSLF
STVPTAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVSSG
AVCSSATLGLSPLQAAASTSASSFQAAASLETRPPPPPPLLPPQHLGRPPAGPPVLHAPP
PPNVALPPPPALLASNPEPVLLQGLASLPANNAFLPPSSAASLQPANASLSVKLASLPHK
VSRPSFTVHHQPLPRLALAQAAPAAPQASSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5211 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcccgtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccatgatgctgctcatgagattatcgagact
atccggtgggtctgcgaggaaatcccggatctcaagctggccatggagaattatgtcctg
attgactatgacaccaaaagttttgaaagcatgcagaggctgtgtgacaaatacaaccgt
gccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaagctgaatact
aggccgtccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactccgtcacc
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtatggggagacgtcc
ttcgacctggtggctcagatgatcgacgagatcaagatgaccgaggatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggtcgctgcggccaccagctgcaag
catcactacggagtggagaaagcggacatcccggccaagtacgcagagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcggaggagtggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggcggcagaatcgtatcctcaaagccctttgcccctctgaacttcaggatcaac
agcaggaacttgagtgacatcggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctctgtgtcgtggactgggaagcctgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactatttttctagtttgaaaaatccaaaactcagggaggagcaggaggca
gcgcgacgccggcagcagcgggagaacaagagcaacgcagccacccccaccaaggtccct
gagggcaaggcgggcaccacggaggcccctgcggattctggtgctgaggaagaaaagtca
ggtgtggccactgtcaaaaagccatctccttccaaagcccggaagaagaaactcaacaag
aaagggagaaagatggctggccggaagcgcgggcggcccaagaaaatgagtgctgcaagt
gcagagcgcaagtccaagaagagccaaagtgcactggatctcctgcgctctccgccccca
gccccaccctcagcctcaccccaggatgcatacaggccacctcacagcccattctaccac
ctacctccgagcacacagctccactcgcccaatccactgctggtggcccccaccccgcct
gcattgcagaagcttttagagtccttcaagatccagtacctgcagttcctggactatacg
aagaccccacaatacaaggccaacctccagaagcttctggaccaggagaaggagaagaac
acacaactgctgggcacggcgcagcagctcttcggtcattgccaggcccagaaggaagag
atccgcaggctgttccaacagaagctggatgagttgggcgtgaaggcgctgacctacaat
gacctgattcaagcccagaaggagatctctgcccacaaccagcagctgcgggagcagtca
gagcagctggagaaggacaacagtgagctgaggagccagagcctgcggctgctcagggcc
cggtgtgaggagctgaggctggactggtccaccctatccctggagaacctgcgcaaagag
aagcaggccctgaggagccagatctcagagaagcagcgacactgcctggagctgcagatc
agcattgtggagctggagaagagccagcgccagcaggagctcctgcagttgaagtcctgt
gtaccgccagatgatgctctgtccctgcatctgcgtggcaagggtgccctgggccgagac
ctggaggctgatgctgggcgcttgcgccttgagctggactgtgccaagatttccctgcca
cacctcagcagcatgagccccgagctctccatgaatggccatgccgccggctacgagctc
tgcagtgcagccagtcggccctcgtccaagcagaacaccccccagtacctggcctccccc
ttggaccaggaggtcgtaccctgcacccctagccatagtagccggcctcgtctagaaaag
tcatctggcttggctctgcctgactatacccgcttgtcacctgccaagattgtgttgagg
cggcacatgaaccaggaccacagcggggctagcaaagcagctgccagtgagccacaccct
cgggcagagcacgccaaggagagcagccttccttaccaaagccccggcttgtccaacagc
atgaagctcagcccccaggatccaccactggcctccccggcgacctcgcccctcacctcc
gaaaagggtagtgagaagggtgtgaaggagcgtgcctacagcagccatggggagaccatc
accagcctgcctgtcagcattccgcttagcacagtccagcccaacaagctgcctgtcagc
atcccactggccagcgtggtgctgcccagccgtgccgagagggcgaggagcactcccagc
cctgtgccgcagccccgagactcctcatccacacttgaaaagcagatcggtgcttccgcc
catggtgcaggggccagtgcagcagggagcaagagcctcgccctgggacccacaggcttc
tacactggctccgtggccatcagcggggccctggccagcagcccagcacctctggcccct
ggaatggagtctgctgttttcgaagagtcctctggccctggcagcctcttcgccagcatg
gggtcccgcagcacacctccacagcacccgcctctgctgccgcagtcccgcaattccggc
cctgcctctcctggccaccaactcgcagccagtccacgcctgagtgtgaccacccagggt
cccctgccggacaccggcaagggggagctgccttccgaccctgccttctccgacccagag
agtgaagctaagaggaggattgtgttcagcatcgccgccggttccagctccaagcagtcg
ccttccaccaggcacagccccttgacctctggcacccgtggggactgtgtacagaaccac
gggcaggatagtcgtaagcgcagcagaaggaagcgtgcgtcagccggaaccccaagcctc
agcacgggtgtatcccccaagcgccgggctctgccggctgtcgctggcctcttcacacag
tcctctgggtctcctctcaaccttaactccatggtcagcaacatcaaccagcccctggag
atcacagccatctcatcccccgagaactccctcaagagctcccccacgccctaccaggac
cacgatcagcctccggtgctcaggaaggagcggcccctgggccctaccaatggggcccat
tactcgccgctgacctcagacgaggagccaggctctgaggacgagcccagcagtacccga
attgagagaaaaattgcaacaatctccttagaaagcaagtctcccccaaagacgctggaa
aatggtggtggcttagcgggaaggaagtcagccccctcaagcgagcccataaacagcagc
aaatggaagtccaccttctcgcctatctccgacctcagcttggccaaggccgtggacagt
ccgctgcaggctggctctgcgctgagccacagccccctgttctctttccggccggcccta
gaggagcccgctgctgaggccaagcttcccacccacccaaggaagagctttgccggctct
ctggctccagctgagggaccgagccctggcgctaatcctcccaacggcctggccttcagc
ggaggcctcgctgcagacctcggtttacacagcttcaacgacggtgcttccctctcccac
aagggccccgatgtgaccggcctgagtgcctccctgagcttcccgtcccagaggggcaag
gacagtaccacagaagccaaccccttcctcagcaggcggcagccggagggcctgggtggc
ctgaagggcgagggcaatgcgggcaaggagtcaggcgaggccctgcccccgtgcgggccg
gcggacaaggccacactgccacatggtagcagggccagcaaaggccgtgatcgcgagctg
gacttcaagggtggccacaacctcttcatctccgctgcagctgtgcctccaggtggcctc
ctcggtggccctggtcttgtaactgtggcttcctctgcgggcagtgcgacgcccactgcc
caggccccccggcctttcctgagcaccttcaccccagggccccagtttactctgggaccc
atgtccctgcaggccaacctgggctctgtggctggctcctccgtgcttcagtccttgttc
agcactgtgccgactgccgcaggcctagtgcatgtatcatccactgcgacccgactgacc
aactcgcacaccatgggcagcttctcctccggggtggccggcggaaccgttggaggtgtc
tttacccacgcggtgccctccgcctctgctcacccgtttggagctggcgtcagcagcggg
gctgtgtgtagcagtgccacgctgggcctgagcccgctgcaggcggcggccagcacctcg
gcttcttcctttcaggccgcggcttcccttgagactcggccgccccctccacctccccta
cttcctcctcagcacctgggccggccccctgcggggccacctgtcctccatgcaccccct
cctcctaacgtcgccttgcctcctccgcctgcgctgctggcttctaaccctgagccagtg
cttctgcagggcctggcttccctcccggctaacaacgctttcttacccccctcctctgcc
gcctctctgcagcctgctaatgcctctctatctgtcaagctcgcctccctcccacacaag
gtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggccctggcacag
gccgcgcccgcagccccacaggccagctcctcggggccatctgctgtgtgggtttccctt
ggcatgccgcctccttatgccgcgcacctttcgggggttaagcctcgataa
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