KEGG   Meriones unguiculatus (Mongolian gerbil): 110563159
Entry
110563159         CDS       T05884                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00562  Inositol phosphate metabolism
mun01100  Metabolic pathways
mun04015  Rap1 signaling pathway
mun04020  Calcium signaling pathway
mun04022  cGMP-PKG signaling pathway
mun04062  Chemokine signaling pathway
mun04070  Phosphatidylinositol signaling system
mun04071  Sphingolipid signaling pathway
mun04072  Phospholipase D signaling pathway
mun04081  Hormone signaling
mun04082  Neuroactive ligand signaling
mun04261  Adrenergic signaling in cardiomyocytes
mun04270  Vascular smooth muscle contraction
mun04310  Wnt signaling pathway
mun04371  Apelin signaling pathway
mun04540  Gap junction
mun04611  Platelet activation
mun04613  Neutrophil extracellular trap formation
mun04621  NOD-like receptor signaling pathway
mun04713  Circadian entrainment
mun04720  Long-term potentiation
mun04723  Retrograde endocannabinoid signaling
mun04724  Glutamatergic synapse
mun04725  Cholinergic synapse
mun04726  Serotonergic synapse
mun04728  Dopaminergic synapse
mun04730  Long-term depression
mun04742  Taste transduction
mun04750  Inflammatory mediator regulation of TRP channels
mun04911  Insulin secretion
mun04912  GnRH signaling pathway
mun04915  Estrogen signaling pathway
mun04916  Melanogenesis
mun04918  Thyroid hormone synthesis
mun04919  Thyroid hormone signaling pathway
mun04921  Oxytocin signaling pathway
mun04922  Glucagon signaling pathway
mun04924  Renin secretion
mun04925  Aldosterone synthesis and secretion
mun04926  Relaxin signaling pathway
mun04927  Cortisol synthesis and secretion
mun04928  Parathyroid hormone synthesis, secretion and action
mun04929  GnRH secretion
mun04933  AGE-RAGE signaling pathway in diabetic complications
mun04934  Cushing syndrome
mun04935  Growth hormone synthesis, secretion and action
mun04961  Endocrine and other factor-regulated calcium reabsorption
mun04970  Salivary secretion
mun04971  Gastric acid secretion
mun04972  Pancreatic secretion
mun04973  Carbohydrate digestion and absorption
mun05010  Alzheimer disease
mun05016  Huntington disease
mun05017  Spinocerebellar ataxia
mun05022  Pathways of neurodegeneration - multiple diseases
mun05142  Chagas disease
mun05143  African trypanosomiasis
mun05146  Amoebiasis
mun05163  Human cytomegalovirus infection
mun05200  Pathways in cancer
mun05415  Diabetic cardiomyopathy
mun05417  Lipid and atherosclerosis
Module
mun_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mun00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    110563159
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110563159
   04310 Wnt signaling pathway
    110563159
   04371 Apelin signaling pathway
    110563159
   04020 Calcium signaling pathway
    110563159
   04070 Phosphatidylinositol signaling system
    110563159
   04072 Phospholipase D signaling pathway
    110563159
   04071 Sphingolipid signaling pathway
    110563159
   04022 cGMP-PKG signaling pathway
    110563159
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    110563159
   04081 Hormone signaling
    110563159
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    110563159
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110563159
   04613 Neutrophil extracellular trap formation
    110563159
   04621 NOD-like receptor signaling pathway
    110563159
   04062 Chemokine signaling pathway
    110563159
  09152 Endocrine system
   04911 Insulin secretion
    110563159
   04922 Glucagon signaling pathway
    110563159
   04929 GnRH secretion
    110563159
   04912 GnRH signaling pathway
    110563159
   04915 Estrogen signaling pathway
    110563159
   04921 Oxytocin signaling pathway
    110563159
   04926 Relaxin signaling pathway
    110563159
   04935 Growth hormone synthesis, secretion and action
    110563159
   04918 Thyroid hormone synthesis
    110563159
   04919 Thyroid hormone signaling pathway
    110563159
   04928 Parathyroid hormone synthesis, secretion and action
    110563159
   04916 Melanogenesis
    110563159
   04924 Renin secretion
    110563159
   04925 Aldosterone synthesis and secretion
    110563159
   04927 Cortisol synthesis and secretion
    110563159
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110563159
   04270 Vascular smooth muscle contraction
    110563159
  09154 Digestive system
   04970 Salivary secretion
    110563159
   04971 Gastric acid secretion
    110563159
   04972 Pancreatic secretion
    110563159
   04973 Carbohydrate digestion and absorption
    110563159
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    110563159
  09156 Nervous system
   04724 Glutamatergic synapse
    110563159
   04725 Cholinergic synapse
    110563159
   04728 Dopaminergic synapse
    110563159
   04726 Serotonergic synapse
    110563159
   04720 Long-term potentiation
    110563159
   04730 Long-term depression
    110563159
   04723 Retrograde endocannabinoid signaling
    110563159
  09157 Sensory system
   04742 Taste transduction
    110563159
   04750 Inflammatory mediator regulation of TRP channels
    110563159
  09159 Environmental adaptation
   04713 Circadian entrainment
    110563159
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110563159
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    110563159
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110563159
   05142 Chagas disease
    110563159
   05143 African trypanosomiasis
    110563159
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110563159
   05016 Huntington disease
    110563159
   05017 Spinocerebellar ataxia
    110563159
   05022 Pathways of neurodegeneration - multiple diseases
    110563159
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110563159
   05415 Diabetic cardiomyopathy
    110563159
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    110563159
   04934 Cushing syndrome
    110563159
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mun04131]
    110563159
Enzymes [BR:mun01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     110563159
Membrane trafficking [BR:mun04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    110563159
 Endocytosis
  Macropinocytosis
   Phospholipase C
    110563159
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 PLC-beta_C EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 110563159
NCBI-ProteinID: XP_060227811
LinkDB
Position
18:complement(6384054..6752402)
AA seq 1207 aa
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCVFKVDEFGFFLTWKSEGKEGQVL
ECSLINSIRLAATPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAESPE
VTKQWVEGLRAIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM
MEAGESAAPASILEDDNEEEIESAADQEEEAHPEYKFGNDLSADDFGHKEAVANSVKKTS
DDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERN
VHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMV
SLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV
ISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDL
AVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDG
FGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTP
QSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHA
KEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEIKKETEIKIQTLTS
DHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLRKLLISAHEQQTQQLKL
SHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAM
KQSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSS
VKLQGAN
NT seq 3624 nt   +upstreamnt  +downstreamnt
atggccaaaccttatgaatttaactggcagaaggaagtgccctctttcttgcaagaagga
gcagtttttgacagatatgaagaggaatcttttgtgtttgagcccaactgcgtcttcaaa
gtggatgaatttggcttcttcctcacctggaagagtgaaggcaaggaaggacaagtgcta
gaatgttccctcatcaacagtatccggctggcagccacaccaaaggatcccaaaatcctg
gctgccctcgaagctgttggaaaatctgaaaatgatctggaagggcggatattgtgtgtc
tgcagcggcacggatctggtgaacatcggctttacctacatggtggctgaaagcccagaa
gtaacaaagcaatgggtagaaggcctgagagcaatcatccacaacttcagagcgaacaac
gtcagccccatgacgtgcctcaagaagcactggatgaaactggcctttctgaccaacacc
agtggtaaaataccggtgaggagtattactagaacctttgcatcggggaaaacagaaaag
gtcatctttcaagcgctcaaggaactaggtcttcccagtggaaagaatgatgaaatcgag
cctgctgcatttacttatgaaaagttctatgaactgacacaaaagatttgtcctcggaca
gatatagaagatctctttaaaaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaacgaacaccaacgagatcctcggctgaatgaaatcttattc
ccattttatgatgctaaaagagcaatgcagatcattgagatgtatgagcctgatgaagat
ttaaagaaaaagggcctcatatcaagcgatgggttctgcagatacctgatgtcagatgag
aatgccccggtcttcctggaccgcctggaactttaccaggagatggaccaccccctggct
cactacttcatcagttcttcccacaacacctatctcactggccggcagtttggtggcaag
tcgtcagtggagatgtacagacaagtactcctggctggctgcaggtgtgttgaacttgac
tgttgggatggaaagggcgaggatcaggaaccgataataactcacggaaaagcaatgtgt
actgacatcctttttaaggatgtgattcaagccatcaaggaaacagcatttgtcacatca
gaatatcccgtaattctctcctttgaaaaccactgcagcaaatatcaacagtacaagatg
tccaagtattgtgaagatctatttggggatctcctgttgaaacaggcgcttgaatcacat
ccccttgaaccaggcaggccgttgccatccccgaatgacctcaaaagaaaaatactcatc
aaaaataaaaggctgaaacctgaagttgaaaaaaaacagcttgaagctttgaaaagcatg
atggaagctggagaatcagctgccccagctagcatcttagaagatgacaatgaagaggaa
atagaaagtgcagctgatcaagaggaggaagcccaccctgaatacaaatttggaaatgac
ctttctgccgacgacttcggtcacaaggaagcagttgcaaacagcgtcaagaagacctca
gatgaccttgaacatgaaaacaacaaaaagggcctggtcactgtagaagatgagcaggca
tggatggcatcttataaatacgtaggtgctaccacgaatatccatccgtacttgtccaca
atgatcaattacgcacagcctgtgaagtttcaaggtttccatgtggctgaagagcgcaat
gttcattacaacatgtcttcttttaacgagtcagttggccttggctacttgaagacacac
gcgattgaatttgtaaattacaataagcgacaaatgagccgcatctaccccaagggaggc
cgagttgattccagtaattacatgcctcagattttctggaatgctggttgccagatggtt
tcactgaactatcaaactccagatttagctatgcagttgaatcaaggaaaatttgagtat
aacggatcctgtgggtaccttctcaagccagatttcatgaggcggcctgaccggacgttt
gatcctttctcagaaacccctgtggatggggtcatcgcagccacgtgctcagtgcaggtt
atatcagggcagttcctgtcagataagaagatcggcacctacgtggaggtggatatgtat
gggttaccgaccgacaccatccggaaggagttccgaacccgcatggtcatgaacaatgga
ctcaacccagtttacaatgaagaatcattcgtgtttcggaaggtgatcctgcctgacctg
gctgtcctgagaattgcagtgtatgatgacaacaacaagctgattggccagaggatcctt
cctttggatggcctccaagcaggctaccgacacatctccctaagaaatgagggaaacaag
ccgttatcactgccaacagttttctgcaatattgttcttaaaacatatgtgcctgatgga
tttggagatattgtggatgctttatccgatccaaagaaatttctttcaatcacagaaaag
agagcagaccaaatgagagctatgggcattgaaactagtgacatagcagatgtgcccagc
gacacttccaaaaatgacaaaaaaggcaaggccaacccggccaaagcgaacgtgacccct
cagagcagctctgagctcagaccaaccaccacagccgccctgggctctggccaggaagcc
aagaaaggtattgaacttatccctcaagtgaggatagaagatttaaagcaaatgaaggca
tacttgaagcatttaaagaagcaacagaaggagttaagctctttaaagaagaagcatgca
aaggagcacagcaccatgcagaagttacactgcacacaagttgacaaaattgtggcccag
tacgacaaagagaagtcaacacatgagaaaatcctagagaaggcgatgaagaagaagggg
ggaagtaattgtcttgaaataaaaaaagaaacagaaattaaaattcagaccctgacatca
gatcacaaatctaaggtcaaagagatcgtggcgcagcacacaaaggagtggtcagagatg
atcaacactcacagcgccgaggagcaagagatccgggatctgcacctgaaccagcagtgt
gagctgctgaggaagctgctcatcagtgctcatgagcagcagacccagcagctgaaactc
tcccatgacagggaaagcaaggagatgcgagcccatcaggctaagatttctatggaaaat
agcaaagccatcagtcaagataaatccatcaagaataaggcagaaagggagaggcgagtc
agggagttgaacagcagcaacacaaaaaagtttctagaagaaagaaagagactggcaatg
aagcagtcaaaagaaatggatcaattgaagaaggtccaactggagcacctggaattcctt
gagaaacagaatgagcagcttttgaaatcctgtcatgcagtgtcccaaacacaaggcgaa
ggagatgcagcagatggtgaaattggaagccgagatggaccgcagaccagcaacagtagt
gtgaagctgcagggtgcgaactga

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