KEGG   Meriones unguiculatus (Mongolian gerbil): 110566227
Entry
110566227         CDS       T05884                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X2
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun01521  EGFR tyrosine kinase inhibitor resistance
mun01522  Endocrine resistance
mun04012  ErbB signaling pathway
mun04015  Rap1 signaling pathway
mun04062  Chemokine signaling pathway
mun04081  Hormone signaling
mun04137  Mitophagy - animal
mun04144  Endocytosis
mun04360  Axon guidance
mun04370  VEGF signaling pathway
mun04510  Focal adhesion
mun04520  Adherens junction
mun04530  Tight junction
mun04540  Gap junction
mun04611  Platelet activation
mun04613  Neutrophil extracellular trap formation
mun04625  C-type lectin receptor signaling pathway
mun04727  GABAergic synapse
mun04750  Inflammatory mediator regulation of TRP channels
mun04810  Regulation of actin cytoskeleton
mun04912  GnRH signaling pathway
mun04915  Estrogen signaling pathway
mun04917  Prolactin signaling pathway
mun04919  Thyroid hormone signaling pathway
mun04921  Oxytocin signaling pathway
mun04926  Relaxin signaling pathway
mun05100  Bacterial invasion of epithelial cells
mun05135  Yersinia infection
mun05152  Tuberculosis
mun05161  Hepatitis B
mun05163  Human cytomegalovirus infection
mun05167  Kaposi sarcoma-associated herpesvirus infection
mun05168  Herpes simplex virus 1 infection
mun05203  Viral carcinogenesis
mun05205  Proteoglycans in cancer
mun05207  Chemical carcinogenesis - receptor activation
mun05208  Chemical carcinogenesis - reactive oxygen species
mun05219  Bladder cancer
mun05417  Lipid and atherosclerosis
mun05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    110566227 (Src)
   04015 Rap1 signaling pathway
    110566227 (Src)
   04370 VEGF signaling pathway
    110566227 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    110566227 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    110566227 (Src)
   04137 Mitophagy - animal
    110566227 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110566227 (Src)
   04520 Adherens junction
    110566227 (Src)
   04530 Tight junction
    110566227 (Src)
   04540 Gap junction
    110566227 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110566227 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110566227 (Src)
   04613 Neutrophil extracellular trap formation
    110566227 (Src)
   04625 C-type lectin receptor signaling pathway
    110566227 (Src)
   04062 Chemokine signaling pathway
    110566227 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110566227 (Src)
   04915 Estrogen signaling pathway
    110566227 (Src)
   04917 Prolactin signaling pathway
    110566227 (Src)
   04921 Oxytocin signaling pathway
    110566227 (Src)
   04926 Relaxin signaling pathway
    110566227 (Src)
   04919 Thyroid hormone signaling pathway
    110566227 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    110566227 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110566227 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    110566227 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110566227 (Src)
   05207 Chemical carcinogenesis - receptor activation
    110566227 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    110566227 (Src)
   05203 Viral carcinogenesis
    110566227 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    110566227 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    110566227 (Src)
   05168 Herpes simplex virus 1 infection
    110566227 (Src)
   05163 Human cytomegalovirus infection
    110566227 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110566227 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110566227 (Src)
   05152 Tuberculosis
    110566227 (Src)
   05100 Bacterial invasion of epithelial cells
    110566227 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110566227 (Src)
   05418 Fluid shear stress and atherosclerosis
    110566227 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110566227 (Src)
   01522 Endocrine resistance
    110566227 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mun01001]
    110566227 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mun04131]
    110566227 (Src)
Enzymes [BR:mun01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     110566227 (Src)
Protein kinases [BR:mun01001]
 Non-receptor tyrosine kinases
  SRC family
   110566227 (Src)
Membrane trafficking [BR:mun04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    110566227 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    110566227 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    110566227 (Src)
  Macropinocytosis
   Kinases
    110566227 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 110566227
NCBI-ProteinID: XP_021519725
LinkDB
Position
4:complement(121639533..121687427)
AA seq 542 aa
MGSNKSKPKDASQRRRSLEPAENVHGPGGAFPASQTPSKPASADAHRGPSAAFVPPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcaacaaaagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
gcggagaacgtgcacgggccggggggcgccttcccagcctcacagacaccgagcaagccc
gcctccgccgacgcccaccgcgggcccagcgccgccttcgtgccccccgcggccgccgag
cccaagctctttggaggcttcaactcctcggacactgtcacctccccgcagagagcgggg
cctctggcaggtggggtgaccacctttgtggccctctatgactatgagtcacggacagag
accgacctgtccttcaagaaaggggagcggctgcagattgtcaacaacacgaggaaggtg
gatgtcagagagggagattggtggctggcacactcgctgagcacaggacagaccgggtac
atccccagcaactatgtggcgccctccgactccatccaggctgaggagtggtacttcggc
aagatcacaagacgggaatcggagcggctactgctcaatgctgagaacccaagagggacc
ttcctcgtgagggaaagtgagaccacaaaaggtgcctactgcctctctgtgtccgacttc
gacaatgccaagggcctcaacgtgaaacactacaagatccggaaactggacagcggcggc
ttctacatcacctcccgcacccagttcaacagcctgcagcagctcgtggcttactactcc
aaacatgctgacggcctgtgtcaccgcctcactaccgtgtgccccacgtcgaagcctcag
acccagggcctggccaaggatgcctgggaaatccctcgggagtccctgcggctagaggtc
aagctgggccagggctgctttggagaggtgtggatggggacctggaacggcaccacgaga
gtcgccatcaaaaccctgaagccaggcaccatgtctccagaggccttcctgcaggaggcc
caagtcatgaagaaactgaggcatgagaagctggtgcagctatatgccgtggtgtcggag
gaacccatttacattgtgaccgagtacatgagcaaggggagtctgctggactttctcaag
ggggagacaggcaaatacctacggctgccccagctggtggacatggctgctcagatcgcc
tcgggcatggcgtatgtggagcggatgaactacgtgcaccgggacctccgagccgccaat
atcctggttggagagaacctggtgtgcaaagtggctgactttgggctggcccggctcatc
gaggacaacgagtacacggcccggcaaggtgccaagttccccatcaagtggacggcgcct
gaagccgcgctgtacggcaggttcaccatcaagtccgacgtgtggtccttcgggatcctg
ctgaccgagctcaccacgaagggacgagtgccctaccctgggatggtgaaccgcgaggtg
ctggaccaggtggagcgcggctaccggatgccgtgtccccctgagtgccccgagtccctg
cacgacctcatgtgccagtgctggcggaaggagcccgaggagcggcccaccttcgagtac
ctgcaggccttcctggaggactacttcacatccaccgagccgcagtaccaacccggggag
aacctatag

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