KEGG   Meriones unguiculatus (Mongolian gerbil): 110566524
Entry
110566524         CDS       T05884                                 
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00562  Inositol phosphate metabolism
mun01100  Metabolic pathways
mun04014  Ras signaling pathway
mun04015  Rap1 signaling pathway
mun04020  Calcium signaling pathway
mun04024  cAMP signaling pathway
mun04070  Phosphatidylinositol signaling system
mun04919  Thyroid hormone signaling pathway
mun04933  AGE-RAGE signaling pathway in diabetic complications
mun05205  Proteoglycans in cancer
Module
mun_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mun00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    110566524 (Plce1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110566524 (Plce1)
   04015 Rap1 signaling pathway
    110566524 (Plce1)
   04020 Calcium signaling pathway
    110566524 (Plce1)
   04070 Phosphatidylinositol signaling system
    110566524 (Plce1)
   04024 cAMP signaling pathway
    110566524 (Plce1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    110566524 (Plce1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110566524 (Plce1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    110566524 (Plce1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mun04131]
    110566524 (Plce1)
Enzymes [BR:mun01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     110566524 (Plce1)
Membrane trafficking [BR:mun04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    110566524 (Plce1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    110566524 (Plce1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like
Other DBs
NCBI-GeneID: 110566524
NCBI-ProteinID: XP_060244978
LinkDB
Position
1:53914001..54204498
AA seq 2312 aa
MTSEEMSTSVLRPVTPRNVASAQPAAEKGEKASDAGVAKARASSRGRLIAHTVSPWHNPT
QDSSRGDLSSVVPRARGETASGEDRSEKRWEETLPASVDGDGSGQSRQHDLPRSRLCGVC
DPRAEEDLGWQTGIPSPLERKALPGIHLATEDSPMDASPSGNQPGVTQSSGPHPDSSMAV
FHFRYEADRTVSDAFHTLSEKLILDDCANCVTLPGGQQKKSYTAYTCKLVELTKNCGEKN
GRLQCDHCSSLPDKHLCFEGSFQKANAVCSGQGGFCREGLTHSPPTKTCLSPLEDLSDSC
EEVDDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLAAWNFIDQKK
AGLLWPCGNVLKPLGIRQNGSQCLSEAQWCLIYSAVRREETEDTVGSLLHCSTHLPSSEA
AHGTIRAGLCLKQCGRDPKCEYRATLQRTSIAQYITGSLLEATTSSGARSSLLSTFGGST
GRIMLKERQPGTSMANSNPVPSSSAGISKELIDLQPLIQFPEEVASILTEQEQNIYRRVL
PMDYLCFLTRDLSSPECQRSLPRLKASISESILTAQRGEHNALEDLVIRFNEVSSWVTWL
ILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDIETM
RSLKDAMAQHESSVEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASSLLKLGPRYS
SHEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLEMEEEDSSSE
GTGSRKNSLKEKTRWQFIIGDLLDSENDIFEKSKECDPHGSEESQKAFDHGTELIPWYVL
SIRADVHQFLLQGATAIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTASPAGTRPKLGML
SNMAEPGKLPSLGNAGLSGLSEGILDLFSVKAVYMGHPGIDIHTVCVQNKLSSMLLSETG
VTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTTAVRKIRKFPDQRQQWLRKQYVSLY
QEDGRYEGPTLAHAVELFGGRRWSTRNPSPGMSAKNAEKPNMQRNNTLGISATKKKKKML
MRGESGEVTDDEMATRKAKLYRECRSRSGSDPQDGNDQEESEANGNTNPPNPLHSRRAHS
LTTAGSPNLATGMSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMVSDS
NMSFVEFVELFKSFSIRSRKDLKDIFDIYSVPCNRSAAESGPLYTNLTIEENTSDLQPDL
DLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLND
FLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKNDESRENK
KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIY
HGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKGVFGEKLVA
KFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAFTGGN
ANPTPASNEEEEDEEDEYDYDYESLSDADVLTASPVPNSQEDNILEDRPENKSCSDKLQF
EYNEEIPKRIKKADNSSCNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLIIYCQAVKF
PGLSTLNSSGSSRGKERKSRKSIFGNNPGRMSPGETASFNRTSGKSLGSCEGIRQTWEEV
SPLSPSTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDS
SNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKSCPMYQKF
SPLERDLDSMDPAIYSLTIISGQNVCPSNSTGSPCIEVDILGTPLDSCHFRTKPIHRNTL
NPMWNEQFLFRVHFEDLVFLRFAVVENNSSAITAQRIIPLKALKRGYRHLQLRNLHNEIL
EISSLFINSRRMEECPSGNTMPASVMFTSEERKCSQTHRVTVHGVPGPEPFAVFTVSGGT
KAKQLLHQILALNQDTKLTTTDYFLMEEKYVISKEKNECKKQPFQRAVGPEEDIMQILNS
WFPEEGYVGRIVLKPQQETLEEKSIVQDDREVILSSEEESFFVQVHDVSPEQPRTVIKAP
RVSTAQDVIQQTLCKAKYSYSILNNPNPSDYVLLEEVMKDGPSKKSSAPKSSQRILLDQE
CVFQAQSKWKGAGKFILKLKEQVQASREDKRRGISFASEFKKLTKSTKQPRALTSPPQLV
ASESVQSKEERPVGALSPSDTVGTSSERGQQV
NT seq 6939 nt   +upstreamnt  +downstreamnt
atgacttccgaagaaatgtccacttccgtcctcaggcctgtgactccgaggaacgtggct
tcggcccagccagcggcggagaagggcgaaaaggcctcagatgccggtgtcgccaaggcg
cgagccagcagccggggcaggctgatcgctcacaccgtctcaccgtggcacaaccccacg
caggactcttccaggggcgatctgtccagcgtcgtcccgagagccaggggggaaacagcg
agcggtgaggaccgcagcgagaagcgctgggaggaaaccctaccggcttccgtagacggc
gacggctcagggcaaagccgccagcatgaccttcctcggagccggctctgtggagtctgc
gacccccgcgccgaggaggacctgggttggcaaactggaattccttctcccctggaaagg
aaggcgctccccggaattcacctggccacggaggactctcccatggacgcgagcccttcg
ggaaatcagcccggggtcacgcagtccagcgggcctcaccctgacagcagcatggcggtg
tttcatttccgctacgaagctgacagaacggtgtcggatgcttttcacaccctgtcagag
aagttaattttggatgactgtgcaaactgtgtcacccttcccggggggcagcagaagaaa
agttacacggcgtatacttgtaaactggtggaactgaccaaaaactgtggtgagaagaat
gggcggctgcagtgtgatcactgcagctcgctgcccgataaacacctttgctttgagggc
tccttccagaaggccaacgcggtctgctcaggtcaaggtggcttttgcagggagggcctt
actcacagtcctcctaccaagacttgcctgagccctttggaggatctctctgacagttgt
gaagaagtagacgattttttcaaaagcaaaaaggaacggtccactttgttagtcagacgg
ttttgtaaaaacgacagggaagttaagaaatctgtgtatactgggacaagagccatcatg
agaaccctgccttctggccatattgggctggctgcttggaatttcattgatcagaagaaa
gccggtcttttatggccttgtgggaatgtactgaaacctctgggcataaggcaaaatggg
agccaatgtctgtctgaagcccagtggtgtctgatctacagtgcagtgagaagagaagaa
acagaagatacagttggatctcttctccattgctccacacatctcccaagctctgaggca
gcccatggaacgattagagctggcctgtgcttaaagcaatgtggacgagaccccaaatgt
gagtaccgtgccaccctccaaaggacatccatagcccagtatatcaccggttctctcctc
gaggcaaccacatcttcaggagcaagaagcagccttctcagtaccttcggaggatccact
ggacgaataatgctgaaagaacgccaaccaggcacctctatggccaactccaatcctgtc
ccttcaagttcagctgggatcagcaaggagctgattgatctccagcctctcattcagttt
ccagaggaagtggccagcatcttgacagaacaggagcagaacatttaccgcagggtcctg
cccatggactacctctgtttcttaacccgggacttgagttctcctgaatgccagagatcc
ctgccccgtctcaaagcatccatctcagaatccatcctcacggctcagagaggagagcac
aatgcccttgaagacctcgtgataagatttaatgaggtgagctcctgggtaacatggctg
atcctcactgcaggctccatggaggagaagcgggaagtcttctcgtatttagtgcatgtg
gccaaatgctgctggaacatgggcaactacaacgctgtcatggagttcctggctggcctc
aggtcgaggaaagttctgaagatgtggcagttcatggaccagtctgacattgagaccatg
cggagcctaaaggatgccatggcccagcatgagtcttccgtggaatacaagaaggtagtg
acccgtgccctgcacatccccggctgcaaggtggttcccttctgcggggtgttcctgaag
gagctctgtgaggtgcttgatggtgcctccagcctcctgaagctcggcccacggtacagc
tcccacgaagaagctctggagtttgtagccgattacagtggacaagataacttcttacaa
cgagtgggacagaatggcttaaaaaattcagagaaggagtccacagtcaacagcatcttt
cagatcatccggagctgcagtcgaagcttggagatggaggaggaggacagctccagcgaa
gggacaggctctaggaaaaactccctgaaggagaaaacccgatggcagtttataatcggt
gatttgctggactcagaaaatgacatctttgaaaagtccaaagaatgtgaccctcatggg
tcagaggagtcacagaaagcctttgaccatgggacagagctcatcccatggtatgtgctg
tccatccgagctgacgtgcaccagttccttttgcagggggccaccgccatccactatgac
caggacacacatctctcagcccgctgctttctccagttgcagcctgacaatagcactctg
acctggatgaagcctcccactgcctcccctgctggtaccagacccaagcttgggatgctt
agtaacatggctgagcctggcaagctcccatcactgggcaacgctgggctgagtggcctg
tcagagggaatcctggatctgttttcagtgaaggctgtgtacatgggacaccctggcatt
gatatacacacggtgtgtgtccagaacaaactgagtagcatgcttctgtcagagactggc
gtgacactgctctatgggcttcagaccaccgacaataggttattgcactttgtggcacca
aagcacacagctaaaatgcttttcagtggattgctggaactcactacagctgtgagaaag
ataaggaagttccctgatcaaagacagcagtggcttcggaaacagtatgtcagcctctat
caggaggatggtcggtatgaaggcccaaccttggctcacgctgtggagttgtttggtggc
aggcgatggagcactagaaaccccagccctgggatgtcagcaaagaatgctgagaagccc
aacatgcagagaaacaataccctgggcataagcgccaccaagaaaaagaagaagatgctc
atgaggggagagagtggagaagtgactgatgatgagatggcaactcgcaaggccaaactg
tacagagagtgccgaagccggagcggctctgatcctcaggacggtaacgatcaggaagag
tcagaggccaatggcaacactaaccctcccaaccccctccattccagaagagcccactct
ttgaccacggctggctcccccaacttggctaccgggatgtcatctcccatcaggccagtc
tcctcccctgtgctgtcttcttcaaacaagagtccatccagtgcctggagcagcagcagc
tggcatgggcggatcaaaggaggaatgaagggcttccagagcttcatggtttcagacagt
aacatgagtttcgttgaatttgttgagctgttcaaatcgttcagcataaggagccgcaag
gacttgaaggatatctttgacatctactctgtgccctgcaatcggtctgctgctgagtca
ggcccgctgtacaccaacctgactatcgaagaaaacaccagtgaccttcagcctgaccta
gatttgctgaccagaaacgtctcagacttggggctgttcatcaagagcaaacagcagctt
tctgacaatcagaggcaaatatctgatgctattgccgctgcaagcattgtgactaatggc
accgggattgagagcacatccctgggcatatttggggttggcatactccagctcaatgac
ttcctggtgaattgccaaggagaacactgcacatatgatgaaatcctcagcatcatccag
aagttcgagcctagcatcagcatgtgtcatcagggcctaatgtcatttgaagggtttgca
aggtttctgatggataaagataatttcgcctccaaaaatgatgagtcgagggagaacaag
aaagaactgcagctacccctctcctactattacattgaatcttcacacaacacctacctc
acaggtcatcagctcaagggagaatcatcggtggagctctacagccaggtcctcttgcaa
ggatgcagaagcgtagagttggactgctgggatggagatgatgggatgcccattatttat
catggacatacactgacgaccaagatccccttcaaggaagtagtggaagccattgatcgc
agtgccttcatcacctctgacctgcccatcatcatatccattgagaaccactgttcgttg
cctcaacaacgaaaaatggcagaaattttcaagggtgtgtttggagaaaagctggtggct
aaattcttatttgagaccgatttctcagatgacccgatgcttccatcacctgatcaactc
aggaggaaagtgctccttaaaaacaagaagctcaaggcccatcagacgccagtcgacatc
ctgaagcaaaaggctcatcagttagcatccatgcaagcacaggctttcactggtggaaat
gccaacccgacacctgccagtaatgaggaagaagaagatgaagaggatgaatatgactat
gattacgaatccctttctgatgcagatgtccttactgcttcccccgttcctaacagtcag
gaagacaatatcctagaagacagacctgaaaacaaatcatgttctgacaagcttcagttt
gagtacaatgaagaaatccccaagaggataaagaaagcagataactcttcctgcaataag
ggaaaggtatatgacatggagctaggagaggagttttaccttcctcagaacaaaaaggaa
agcaggcagatcgcaccagagctctcggacctcatcatctactgccaggctgtaaaattc
ccaggcctgtcaactctgaattcatctggctctagcagagggaaagaaagaaaaagcagg
aagtccatttttggcaacaatcctggcagaatgagcccaggggagacagcatcatttaac
agaacatctggaaaaagtttaggttcctgtgaaggaattcgacaaacctgggaggaagtg
tctccactcagcccaagcacatccctcagcgctatcattaggactcctaaatgttatcat
atctcgtcactgaacgaaaatgccgccaaacgtctgtgtcgaaggtattcccagaaactg
atccagcacactgcttgtcagctgctgaggacctaccctgcagcgacccgaatcgactca
tccaatcccaaccccctcatgttctggctccatgggatacagctcgtagccctaaactac
cagacagatgatcttcctttacatttaaatgccgcaatgtttgaggccaatggtggctgt
ggttatgttttgaagccccctgtcctgtgggataaaagctgtcccatgtaccagaagttt
tctccactggaaagagacctagacagcatggaccctgctatctattccttaactatcatc
tctggccaaaatgtgtgccctagtaacagcacaggaagtccatgcattgaagttgacatc
ttgggcacgcccctggacagctgccatttccgcacaaagcccatccatcgaaacactctg
aaccccatgtggaacgaacagtttctcttccgggttcactttgaagatcttgtgtttctt
cgttttgcagttgtggaaaataacagttcggcgataacggctcagagaatcattccgctc
aaagctttaaaacgaggatatcgacatcttcagctgcggaacctccacaatgaaatcttg
gaaatctctagcttattcataaacagcagaaggatggaagaatgtccctctggcaatacc
atgccagcctctgtgatgtttacttctgaagagaggaagtgttctcagactcacagggtc
acagtgcatggtgtcccaggtccagagcccttcgctgttttcactgtaagtggaggcacc
aaggcaaagcagctcctccatcagattttggcgctcaaccaagacaccaaacttaccacc
acagactattttctgatggaagagaagtatgttatatctaaggaaaagaatgagtgcaag
aaacaaccattccagagagctgtgggtccagaggaagatatcatgcagattttaaacagc
tggttcccagaagaaggctacgtaggcagaattgtcctaaagccccagcaggaaacccta
gaagagaaaagcattgtccaagatgacagagaggtgatcttgagctcggaggaggagagt
ttctttgtccaagtgcatgatgtctccccagagcaaccacgaactgtcatcaaagccccc
cgcgtcagcactgcacaggatgtaattcagcagaccttatgcaaagccaaatattcctac
agcatcctcaacaaccccaacccaagtgactacgtgcttttggaagaggtgatgaaagac
ggacccagtaagaagtcttctgctccaaagtcctcacagaggattcttttggaccaagag
tgtgtgtttcaagcccaaagcaagtggaaaggtgcagggaagttcatccttaagttaaag
gaacaggtgcaggcatcccgagaagataaaaggaggggcatctcctttgcaagtgaattc
aagaaactcaccaagtctactaagcaaccccgagcactcacatcgcctcctcagcttgtg
gcctcagaaagtgtccaaagcaaggaggagaggcctgtgggtgccttgtcccctagtgac
acagtgggtaccagcagtgagcgagggcagcaggtttga

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