Microcaecilia unicolor: 115467201
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Entry
115467201 CDS
T09142
Symbol
GCLC
Name
(RefSeq) LOW QUALITY PROTEIN: glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
muo
Microcaecilia unicolor
Pathway
muo00270
Cysteine and methionine metabolism
muo00480
Glutathione metabolism
muo01100
Metabolic pathways
muo01240
Biosynthesis of cofactors
muo04216
Ferroptosis
Module
muo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
muo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
115467201 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
115467201 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
115467201 (GCLC)
Enzymes [BR:
muo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
115467201 (GCLC)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
115467201
NCBI-ProteinID:
XP_030054827
UniProt:
A0A6P7XH62
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Position
3:complement(458814590..459003576)
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AA seq
637 aa
AA seq
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MGLLSHGSPLSWEETKKYADYVRNHGIVQFLNIYHKVKERQKDVLKWGDEVEYMLLCFDH
SNQKVRLALKGEEILEILQHKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMADFNTV
EDNMRKRRHEASSLLQQNEAICSVTSFPRLGCPGFTLPEYLPTPVEKGASKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVAINVPIFKDRNTQTPFMEKFPSDDGEGGKAAKPDHIYMD
AMGFGMGNCCLQVTFQACSISEARCLYDQLATICPIVMALECCSPFYRGYVSDIDCRWGX
ISASVDDRTQEERGLKPLKNNKYRISKSRYDSIDSYLSKCGEKYNDLDLTIDMXIYKQLV
KEGIDHLVAQHIAHLFIRDPLTLXEEKIHLDDDNESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKAGNAVVEDCGAAQNGTETGAEEYALMSIDTIINGKEGLFPGLIPILN
SYLENMEVDVDTRCTILKYLKLIKKRASGELMTVARWMREFVANHPNYQQDSVITDKMNY
DLLMKCYNIANELTECPELLGRGGDKIKLGDNKMASL
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggcctcctgtctcatgggtcgccgctgagctgggaagagaccaagaagtatgcggac
tatgttcgaaatcacggtatcgttcagtttctcaacatctaccacaaggtcaaagagcgc
cagaaggacgttctgaagtggggcgacgaggtggagtacatgctgttatgttttgatcat
tcaaatcaaaaagtacgcttggcattgaaaggagaagagattctggaaatccttcagcac
aaaggagaaaagacaaatccaaaccatccaactctttggcgaccagaatatggcagctac
atgattgaaggaacaccagggcagccatacggaggcaccatggctgattttaacactgta
gaagataatatgaggaaaagacgacatgaggcttcttctttgttgcaacaaaatgaagct
atttgttcagtgacatcatttccaaggttaggatgcccaggattcacactccctgaatat
ctgcccacaccagtagagaaaggtgcttcaaaatctctattttttccagatgaagcaata
aatagacatcctaggtttagtactttaacaagaaatattcgacacagaagaggagagaaa
gtagcaataaatgtaccaatatttaaagaccggaatacacaaactccatttatggagaaa
tttccaagtgatgatggtgaaggaggaaaggcagctaaaccagatcacatatatatggat
gccatgggttttggtatgggtaactgctgtcttcaggtaacattccaggcatgtagtatt
tctgaagccagatgtctttatgaccagttagcaacaatctgtccaattgtgatggcattg
gagtgctgctctccgttctacagaggttatgtgtcagatattgattgccgctgggganta
atttctgcatctgtagatgacagaacacaagaggagaggggactgaagccactgaagaat
aacaagtacagaataagtaaatccagatatgattccatagacagttacctgtctaaatgt
ggtgagaaatacaatgaccttgatttgacaatagatatgnnaatctataagcaactagtt
aaagaaggcattgaccaccttgtagcacagcatattgcacatctgtttattcgagaccca
cttaccttanttgaagagaaaattcatctagatgatgacaatgaatctgaccattttgag
aatatccagtcaacaaactggcagactatgagatttaaaccaccgcctccaaattctgat
attggctggagagtggaatttcgacccatggaggtccagttaacagactttgaaaactct
gcatatgttgtatttgtggtattactaaccagagtgattctgtcatataagctggatttt
cttattcctctgtcaaaggttgatgaaaatatgaaagttgcccaaaaacgggatgctgtt
cggcagggaatgttttattttagaaaagacatttgtaaagctggtaatgcagttgttgag
gactgtggagcagcccagaacggtactgagacaggtgcagaagagtatgctttaatgagc
attgatacaatcatcaatggaaaggaaggcttatttcctggtttaataccaattctgaac
tcttaccttgaaaacatggaggtggatgtggacacaagatgtaccatattgaaatatctg
aaattaattaaaaagagagcatcaggagaattaatgactgttgctcgatggatgagggag
tttgttgcaaatcatccaaattaccagcaagatagtgtaattacagacaaaatgaactat
gatcttcttatgaagtgttacaatattgcaaatgagttaactgaatgcccagagttactt
ggacgtggaggtgacaaaataaaactcggtgacaataaaatggcctctctttaa
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