Microcaecilia unicolor: 115479478
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Entry
115479478 CDS
T09142
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
muo
Microcaecilia unicolor
Pathway
muo00280
Valine, leucine and isoleucine degradation
muo00640
Propanoate metabolism
muo00785
Lipoic acid metabolism
muo01100
Metabolic pathways
muo01210
2-Oxocarboxylic acid metabolism
Module
muo_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
muo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
115479478 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
115479478 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
115479478 (BCKDHA)
Enzymes [BR:
muo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
115479478 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
DUF6409
Motif
Other DBs
NCBI-GeneID:
115479478
NCBI-ProteinID:
XP_030073261
UniProt:
A0A6P7Z9K2
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Position
11:175097118..175109432
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AA seq
432 aa
AA seq
DB search
MAAVRGLLRGLRRATVSCRTLTLSHARCQHEFTSLEEKPQFPGASAEFVDKLDFIQPNVI
SGIPIYRVMDRQGQIVNPAEDPQLPQEMVLKFYRTMTLLNTMDRILYESQRQGRISFYMT
NYGEEGTHVGSAAALGDRDLVFGQYREAGVLMYRGYPLDLFMSQCYGNSGDQGKGRQMPV
HYGCKDLHFVTISSPLATQIPQAVGAAYAIKRENADRVVICYFGEGAASEGDAHAGFNFS
ATLECPILFFCRNNGYAISTPTSEQYRGDGIAARGPGYGLMSIRVDGNDVFAVYNAVKEA
RRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMVSKHW
WDEEQEKAWRKKSRKMVMEAFEQAERKLKPHPDNLFSDVYSEMPAHIKQQRESLWRHLKI
YGEHYPLDHYEK
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atggcggcagtgcgagggttgctccgggggctgcgccgggccactgtttcctgtaggacc
ctgacactgagtcatgctcgttgtcagcatgagttcacgtccctggaggaaaaaccacag
ttccctggagcttcagctgagtttgtggacaaactggattttattcagcccaatgtgatc
tctgggatccctatctacagggtcatggatcgccaagggcagattgtaaacccagcagaa
gatccccagcttccgcaggagatggtactgaagttctatcgtaccatgacactgctgaac
accatggaccggatcctatatgagtcccagcggcagggtaggatttccttctacatgaca
aactatggagaagagggcactcacgtgggcagtgccgctgcattgggtgaccgagatctg
gtgttcgggcagtacagggaggcaggtgtccttatgtaccgcggttaccccctggacttg
ttcatgtcgcagtgttatgggaatagtggcgaccaagggaaagggcgtcagatgccggtg
cattatggatgcaaggatttgcactttgtgaccatttcttccccactggcaacccagatc
ccacaagccgtgggggccgcctatgccatcaaacgggagaacgctgaccgtgtggtgatc
tgctattttggggagggcgcagccagtgaaggggacgcccatgctggtttcaacttttct
gccacgctggagtgccctattcttttcttctgtcgcaacaatggctatgccatctccacc
cccacctccgagcagtaccggggggatggcattgctgctagaggccctggctatggcctc
atgtccatccgtgtggatgggaatgatgtgtttgctgtatacaacgctgtcaaggaggca
cgacgcagagctgtggcggagaaccagccctttctgattgaggccatgacgtacaggatt
ggacatcacagtaccagcgatgacagctcagcctatcgctctgtggatgaggtgaactac
tgggacaagcaggaccaccctatttcccgccttcgccactacatggtgagcaagcactgg
tgggacgaggagcaggagaaggcctggagaaagaagtctcggaaaatggtcatggaggcc
ttcgagcaggccgaacggaagctgaagccgcacccagataacctgttctctgatgtgtac
tcggagatgccagctcacatcaagcagcagcgcgagtccttgtggagacacctgaagatt
tatggagagcattacccactggaccattatgaaaaatga
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