Mannheimia varigena USDA-ARS-USMARC-1388: X875_7160
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Entry
X875_7160 CDS
T03029
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mve
Mannheimia varigena USDA-ARS-USMARC-1388
Pathway
mve00290
Valine, leucine and isoleucine biosynthesis
mve00620
Pyruvate metabolism
mve01100
Metabolic pathways
mve01110
Biosynthesis of secondary metabolites
mve01210
2-Oxocarboxylic acid metabolism
mve01230
Biosynthesis of amino acids
Module
mve_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mve00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
X875_7160
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
X875_7160
Enzymes [BR:
mve01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
X875_7160
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AHG79334
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Position
755690..757234
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AA seq
514 aa
AA seq
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MSNNNIIIFDTTLRDGEQSLKASLTVKEKLQIALALERLGVDVMEVGFPVSSAGDFDSVQ
TIARHIKNSRVAALSRAVAKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVV
EMAVAAVKRARGYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNE
YGNIIHQVMNRVPNIDKAIVSVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNT
ALEEVVMAIKTRQEFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGI
HQDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYTEADYDLDKLYEA
FLELADKKGQVFDYDLEALAFIDMQQGEENRLKLDVITTQLISGLPASAFVQVELDGVRQ
SATSQGGNGPVEATYNAIMNIVGMELKMSHYNLTAKGEGAEALGQVDIVVEYEGRKFHGV
GLATDIVESSARALIHAINAIYRSQKVADIKAKK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgagcaacaataacattattatttttgatacaacattgcgtgatggtgaacaatcccta
aaagcgagtttaacggtaaaagaaaaattacaaatagcactcgcattggaacgtttaggt
gttgatgtaatggaagttggtttccctgtttcttccgcaggtgattttgattcggtgcaa
actattgcacgtcatatcaaaaacagtcgtgtggcagcactttcccgtgcggtagcgaaa
gatattgatgcggcttatgaagccttaaaagttgctgaagccttccgtattcataccttt
attgctagttcagcgttacacgttgaagcaaaattaaagcgttcatttgatgatgtggtg
gaaatggcagtggcagcagtaaaacgtgccagaggctacaccgatgatgtagaattttcg
tgcgaagatgcaggacgtaccggcattgataacatctgtcgcattgtagaagcagcaatt
aacgctggtgcaactacggtgaacattccggatacggtcggtttctgtttgccgaatgag
tacggcaacattatccatcaagtgatgaaccgagtgccgaatatcgataaagcaatcgtt
tctgtacattgtcataacgatttaggaatggcgaccgccaactcattaactgcggtgcag
aatggagcaagacagatagaatgtaccatcaacggtatcggcgagcgtgcagggaatacg
gcattggaagaagtggtgatggcgatcaaaacccgccaagagtttatgggcgtagatact
cgcatcaatacccaagaaattcaccgtgtcagccaaatggtgagccagctttgcaatatg
ccgattcagccgaacaaagcgatcgtgggcagcaatgcgtttgctcactcatcgggcatt
caccaagacggtatgctgaaaaacaaaaatacctacgaaattatgtcgccggaaaccatc
ggcttaaagaaagagaagcttaatttgactgctcgttcaggtcgtgcagcagttaaagga
catatggcggatatgggctataccgaagcggattatgatttagataaactctatgaagct
ttcctagagcttgctgataaaaaaggacaagtttttgattatgatttagaagctcttgct
tttattgatatgcaacaaggcgaagaaaacagattaaaactggatgtgattacgacccag
ctgattagcggtttgccggcatctgcatttgtgcaggtagaactagacggtgttcgtcaa
agtgcaacttcgcaaggcggtaatggtccggttgaagcaacttacaatgcaattatgaac
attgtgggtatggagcttaaaatgtcgcactataacttaaccgcaaaaggcgaaggagca
gaagctttagggcaggtggatattgtggtggaatatgaaggcaggaaattccatggtgtt
ggtttagcaaccgatattgtcgaaagttcagcacgagcattaattcacgcaattaatgca
atttatcgttcacagaaagtggcagatatcaaagcgaagaaataa
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