Mannheimia varigena USDA-ARS-USMARC-1296: X808_18210
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Entry
X808_18210 CDS
T03027
Name
(GenBank) Glutathione biosynthesis bifunctional protein gshAB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mvi
Mannheimia varigena USDA-ARS-USMARC-1296
Pathway
mvi00270
Cysteine and methionine metabolism
mvi00480
Glutathione metabolism
mvi01100
Metabolic pathways
mvi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mvi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
X808_18210
09106 Metabolism of other amino acids
00480 Glutathione metabolism
X808_18210
Enzymes [BR:
mvi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
X808_18210
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_ST
GARS_A
GCS2
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AHG76341
UniProt:
W0QCT7
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Position
1924671..1926947
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AA seq
758 aa
AA seq
DB search
MKLQQIIRENHLGLLFQQGNFGLEKESQRVDMNGNIVTTPHPAVFGNRSYHPYIQSDFAE
SQLELITPPNAKLEDSFRWLSAIHEVVLRSLPDDEYIYPLSMPAGLPPEEQIQEAQFDNP
DDVKYREYLSKTYGKYKQMVSGIHYNFQLSPEFVEKAFAAQTEYATHKEFQNALYMKLAN
NFLRYQWILLYLLAASPTVESQYFCGKSPLAAGQFVRSLRSSRYGYVNSPEVVVNHDSLQ
SYVESLEAQVVEGLLIAEKEFYSNVRLRGGKKARDLLENGVKYAEFRLFDLNPFAPYGIE
LSDAKFIHTFLLGMLWLEETSGQKEVEIGKQRLYQVAMEDPRSETAFRAEGETVLNQILA
MLETLGSSEENRDLVREKLAQLADPNQTIGGRLIQAIEQFGSDKAVGAKFAQTYKAQAFE
RFYALSAFDNMELSTQALFFDLIQQGISTELLDENDQFLALKFGEHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTTLEEAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQAVKNREDFAKAVEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVV
GDGVHCVKELVDLKNADPLRGDGSRSPLKKIALGEIEQLQLKEQGLTVDSVPEKGQTVQL
RANSNISTGGDSIDMTDQMHESYKQIAVGIAHAMGAKVCGVDLIIPDLTKPAEPHLNSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVIKMLFPELDN
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgaagctacaacaaattatccgagaaaatcatttaggcttgctgttccaacaagggaat
tttggcttggagaaagagagccagcgtgttgatatgaatggtaatattgtcactacgcct
caccctgccgtgtttgggaatcgcagctatcacccttacattcagagcgattttgctgag
agccagctcgaacttattaccccgccgaatgcaaaattggaagacagtttccgctggctt
tctgccattcacgaagtggtgctgcgttcattacctgacgatgaatacatctaccccttg
agtatgcctgccggtttgccgccggaagagcaaattcaagaggctcaatttgataaccct
gatgatgtgaaatatcgggaatatctctccaaaacctatggcaaatataagcaaatggtg
agcggtattcactacaatttccagctctcgcctgaatttgtggaaaaagctttcgccgcc
caaacggaatatgccacgcacaaagagttccaaaatgcgttgtatatgaagctcgctaac
aatttcctgcgttatcagtggattttgctctatctgcttgccgcttcgccaacggtggaa
tcgcaatatttttgcggaaaatcaccgcttgcagccgggcaatttgtccgcagtttgcgt
tccagccgttatggttacgtcaattcgcccgaggtagtcgtgaaccacgacagcctgcaa
agctatgtggagagccttgaggctcaagtggtggaaggcttattgattgcggagaaagag
ttctactccaacgtgcggttgcgtggcggcaaaaaagcccgtgatttgcttgaaaacggc
gtgaaatatgctgagttccgcctgttcgatcttaaccctttcgccccatacggcattgag
ttgagcgatgcgaagtttatccacacgttcttgttaggaatgttgtggctggaggaaaca
agcggtcaaaaagaggtggaaattggcaaacagaggctttaccaagtcgcaatggaagat
ccaagaagcgaaaccgctttccgtgcagagggagagacagttctaaatcagatcctcgca
atgctcgaaaccttaggttcaagcgaagaaaaccgagatctggtgcgggaaaaattagca
caacttgccgatccgaaccaaactatcggtggacgtttgatccaagccatcgaacagttc
ggtagcgacaaagctgttggagcgaaattcgctcaaacttacaaagctcaagcctttgag
cgtttttatgcgttatcggcgtttgacaatatggagctttccacccaggccctattcttt
gatttgatccagcaaggcataagcacggaattattagatgaaaacgatcagttcctcgcc
ttgaaatttggcgaacatctggaatatgtgaaaaacggcaatatgaccagccacgatcaa
tacatttcgccgctcattatggaaaacaaagtcgtgacgaaaaaagtgctggcgaaagcc
ggtttcaacgtgccgaaaagtgtggaatttaccacgctcgaagaggcggtggctcactat
ccgctatttgagggtaaggcagtggtgatcaagccgaaatccaccaactacggtttaggc
atcactattttccaacaagcggtcaaaaatcgggaagattttgcaaaagcggtggaaatt
gcgttccgtgaagacaaagaagtgatggtggaagattatttggtcggcacggaataccgt
ttctttgtgctaggcgatgaaaccctcgccgtgcttctgcgtgtgcctgccaatgtggtc
ggggacggcgtgcattgcgtcaaagagctggtggatctgaaaaatgccgatccgctacga
ggggatggctctcgtagcccgctgaaaaaaattgctttgggtgaaatcgaacagttacag
ctgaaagagcaaggtttaacggtggattctgtgccggagaaaggtcaaaccgtgcaactg
cgagcaaattccaacatcagcaccggcggcgattctattgatatgaccgaccaaatgcac
gaaagctacaagcaaattgcggtaggaattgctcacgctatgggggcgaaagtgtgtggc
gtggatttgattattcctgatctcaccaagcctgccgagccacacctcaactcttggggc
gtgatcgaagcaaatttcaacccaatgatgatgatgcatattttcccatatcaaggaaaa
tctcgccgtttaactaaagcggtgattaaaatgctgtttcctgaattagacaactaa
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