Candidatus Mycobacterium wuenschmannii: PT015_21245
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Entry
PT015_21245 CDS
T09639
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mwu
Candidatus Mycobacterium wuenschmannii
Pathway
mwu00860
Porphyrin metabolism
mwu01100
Metabolic pathways
mwu01110
Biosynthesis of secondary metabolites
mwu01120
Microbial metabolism in diverse environments
mwu01240
Biosynthesis of cofactors
Module
mwu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mwu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mwu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
PT015_21245
Enzymes [BR:
mwu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
PT015_21245
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
PT015_21245
BRITE hierarchy
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WIM87342
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Position
4408283..4409941
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AA seq
552 aa
AA seq
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MTTRGRKPRPGRIMFVGSGPGDPALLTTRAAAVLANAPLVFIDPDVPEAVQALIGKDLPP
VSGPAPAEPAAASENPAEGADAKEQPAAVVSVGPDIRPALGDPTEVAKTLVAEARTGADV
VRLVAGDPLSVDSVITEVNSVARSHLHFEIVPGLAASDAVPTYAGLPLGSSHTVADVRGD
VDWGALAAGPGPLILQATSAHVADSARTLIEYGLADTTPCVVTSSGTTCQQRSVESTLGG
LTDTNLLLAADGAAPSPVVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSER
LTAHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSLGLLDEFPDYDSIFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLIEALAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgcaagccgaggcccggccgcatcatgttcgtgggttcgggtcct
ggcgacccagccctgctgacgacgcgggccgcagcggtgctggccaatgcccccctggtg
ttcattgaccccgacgtgcccgaggcagtgcaggcgttgatcggtaaggatctgccgccc
gtctccgggcccgcgccggccgaaccggcagcggcgtcggaaaacccagcagagggcgcg
gacgcgaaagaacaacccgccgccgtggtgtcggtgggacccgacatccggcccgcgctg
ggcgaccccaccgaggtggccaagacgctggtcgccgaggcccgcactggggccgacgtg
gtgcgcctggtagccggcgacccgctgtcggtcgactcggtgatcaccgaggtcaactcc
gtggcacgcagccacctgcacttcgagatcgtgccgggcctggccgccagcgacgcggtg
ccgacctacgcgggtctgccgctgggctcgtcgcacaccgttgccgacgtccgcggagac
gtcgactggggcgccctggccgccggtccgggtccgctgatcctgcaggccacctcggcg
catgtcgccgactcggcccgcacgctgatcgagtacggcctggccgacaccaccccctgc
gtggtcacctcgtcgggcaccacctgccagcagcgctccgtggagtcgacgctgggcggg
ctgaccgacacgaacctgctgctggccgctgacggcgccgcgccgtcgccggtggtcgtc
accatcggcaagacggtggccaaccgggccaagctgaactggtgggagagccgcgccctg
tacggctggaccgtgctggtgccacgcaccaaggaccaggccggcgagatgagcgagcgg
ctgaccgcgcacggcgcgctgccgatcgaggtcccgacgatcgccgtcgagccgccgcgc
agccccgcccaaatggagcgtgccgtcaagggattggtcgacggccgctaccaatgggtc
gtgttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcggtctc
gacgcccgcgcgttctccggcgtgaagatcgcttgcgtcggcgagtcgaccgcggaccgg
gttcgcgcattcgggatcagccccgagctggtgccctccggcgagcagtcgtcgctgggc
ctgctggacgaattcccggactacgacagcattttcgatccggtcaaccgggtgctgctg
ccgcgtgccgacatcgccaccgagacgctggccgagggtctgcgcgaacgcggctgggag
atcgaggacgtcaccgcgtaccggaccgtgcgcgccgccccgccgccagcggccacccgc
gagatgatcaagaccggcggcttcgacgcggtgtgcttcacctcgagctcgaccgtgcgc
aacctggtcggcatcgccggcaagccgcacgcgcgcaccatcgtcgcctgcatcgggccg
aagaccgctgagacggcagccgaattcggcctgcgcgtcgacgtgcagcccgagaccgcc
gcggtgggcccgctgatcgaagcgctggccgagcacgccgcccggctgcgcgccgagggt
gcgctgccgccgccgcgtaagaagagccgcaggcgctaa
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