Myotis brandtii (Brandt's bat): 102241255 Help Entry 102241255         CDS       T02920                                  Symbol PLCB4 Name (RefSeq) phospholipase C beta 4   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb00562   Inositol phosphate metabolism myb01100   Metabolic pathways myb04015   Rap1 signaling pathway myb04020   Calcium signaling pathway myb04022   cGMP-PKG signaling pathway myb04062   Chemokine signaling pathway myb04070   Phosphatidylinositol signaling system myb04071   Sphingolipid signaling pathway myb04072   Phospholipase D signaling pathway myb04261   Adrenergic signaling in cardiomyocytes myb04270   Vascular smooth muscle contraction myb04310   Wnt signaling pathway myb04371   Apelin signaling pathway myb04540   Gap junction myb04611   Platelet activation myb04613   Neutrophil extracellular trap formation myb04621   NOD-like receptor signaling pathway myb04713   Circadian entrainment myb04720   Long-term potentiation myb04723   Retrograde endocannabinoid signaling myb04724   Glutamatergic synapse myb04725   Cholinergic synapse myb04726   Serotonergic synapse myb04728   Dopaminergic synapse myb04730   Long-term depression myb04742   Taste transduction myb04750   Inflammatory mediator regulation of TRP channels myb04911   Insulin secretion myb04912   GnRH signaling pathway myb04915   Estrogen signaling pathway myb04916   Melanogenesis myb04918   Thyroid hormone synthesis myb04919   Thyroid hormone signaling pathway myb04921   Oxytocin signaling pathway myb04922   Glucagon signaling pathway myb04924   Renin secretion myb04925   Aldosterone synthesis and secretion myb04926   Relaxin signaling pathway myb04927   Cortisol synthesis and secretion myb04928   Parathyroid hormone synthesis, secretion and action myb04929   GnRH secretion myb04933   AGE-RAGE signaling pathway in diabetic complications myb04934   Cushing syndrome myb04935   Growth hormone synthesis, secretion and action myb04961   Endocrine and other factor-regulated calcium reabsorption myb04970   Salivary secretion myb04971   Gastric acid secretion myb04972   Pancreatic secretion myb04973   Carbohydrate digestion and absorption myb05010   Alzheimer disease myb05016   Huntington disease myb05017   Spinocerebellar ataxia myb05022   Pathways of neurodegeneration - multiple diseases myb05142   Chagas disease myb05143   African trypanosomiasis myb05146   Amoebiasis myb05163   Human cytomegalovirus infection myb05200   Pathways in cancer myb05415   Diabetic cardiomyopathy myb05417   Lipid and atherosclerosis Module myb_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:myb00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     102241255 (PLCB4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102241255 (PLCB4)    04310 Wnt signaling pathway     102241255 (PLCB4)    04371 Apelin signaling pathway     102241255 (PLCB4)    04020 Calcium signaling pathway     102241255 (PLCB4)    04070 Phosphatidylinositol signaling system     102241255 (PLCB4)    04072 Phospholipase D signaling pathway     102241255 (PLCB4)    04071 Sphingolipid signaling pathway     102241255 (PLCB4)    04022 cGMP-PKG signaling pathway     102241255 (PLCB4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     102241255 (PLCB4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102241255 (PLCB4)    04613 Neutrophil extracellular trap formation     102241255 (PLCB4)    04621 NOD-like receptor signaling pathway     102241255 (PLCB4)    04062 Chemokine signaling pathway     102241255 (PLCB4)   09152 Endocrine system    04911 Insulin secretion     102241255 (PLCB4)    04922 Glucagon signaling pathway     102241255 (PLCB4)    04929 GnRH secretion     102241255 (PLCB4)    04912 GnRH signaling pathway     102241255 (PLCB4)    04915 Estrogen signaling pathway     102241255 (PLCB4)    04921 Oxytocin signaling pathway     102241255 (PLCB4)    04926 Relaxin signaling pathway     102241255 (PLCB4)    04935 Growth hormone synthesis, secretion and action     102241255 (PLCB4)    04918 Thyroid hormone synthesis     102241255 (PLCB4)    04919 Thyroid hormone signaling pathway     102241255 (PLCB4)    04928 Parathyroid hormone synthesis, secretion and action     102241255 (PLCB4)    04916 Melanogenesis     102241255 (PLCB4)    04924 Renin secretion     102241255 (PLCB4)    04925 Aldosterone synthesis and secretion     102241255 (PLCB4)    04927 Cortisol synthesis and secretion     102241255 (PLCB4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102241255 (PLCB4)    04270 Vascular smooth muscle contraction     102241255 (PLCB4)   09154 Digestive system    04970 Salivary secretion     102241255 (PLCB4)    04971 Gastric acid secretion     102241255 (PLCB4)    04972 Pancreatic secretion     102241255 (PLCB4)    04973 Carbohydrate digestion and absorption     102241255 (PLCB4)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     102241255 (PLCB4)   09156 Nervous system    04724 Glutamatergic synapse     102241255 (PLCB4)    04725 Cholinergic synapse     102241255 (PLCB4)    04728 Dopaminergic synapse     102241255 (PLCB4)    04726 Serotonergic synapse     102241255 (PLCB4)    04720 Long-term potentiation     102241255 (PLCB4)    04730 Long-term depression     102241255 (PLCB4)    04723 Retrograde endocannabinoid signaling     102241255 (PLCB4)   09157 Sensory system    04742 Taste transduction     102241255 (PLCB4)    04750 Inflammatory mediator regulation of TRP channels     102241255 (PLCB4)   09159 Environmental adaptation    04713 Circadian entrainment     102241255 (PLCB4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102241255 (PLCB4)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     102241255 (PLCB4)   09174 Infectious disease: parasitic    05146 Amoebiasis     102241255 (PLCB4)    05142 Chagas disease     102241255 (PLCB4)    05143 African trypanosomiasis     102241255 (PLCB4)   09164 Neurodegenerative disease    05010 Alzheimer disease     102241255 (PLCB4)    05016 Huntington disease     102241255 (PLCB4)    05017 Spinocerebellar ataxia     102241255 (PLCB4)    05022 Pathways of neurodegeneration - multiple diseases     102241255 (PLCB4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102241255 (PLCB4)    05415 Diabetic cardiomyopathy     102241255 (PLCB4)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102241255 (PLCB4)    04934 Cushing syndrome     102241255 (PLCB4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:myb04131]     102241255 (PLCB4) Enzymes [BR:myb01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      102241255 (PLCB4) Membrane trafficking [BR:myb04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     102241255 (PLCB4)  Endocytosis   Macropinocytosis    Phospholipase C     102241255 (PLCB4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X PH_14 PI-PLC-Y DUF1154 EF-hand_like C2 EF-hand_7 EF-hand_6 Motif Other DBs NCBI-GeneID:  102241255 NCBI-ProteinID:  XP_014401959 LinkDB All DBs Position Un AA seq 1204 aa AA seqDB search MAKPYEFNWQKEVPSFMQEGAIFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVL ECSLINSIRLGATPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNISFTYMVAENPD VTKQWVDGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEQKQLEALKSM MEAGESAAPVSILEDDNEEXIESVDQEEEAHPEYKFGSELDDLGHKEVVANSVKKVSDDL EHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHY NMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLN YQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISG QFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVL RIAVYDDNNRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGD IVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKTNVTPQSS SELRPTTTAALGSGMEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEH STMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHK SKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHD RESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQS KEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSCMKL QNTN NT seq 3615 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccttatgaatttaactggcagaaggaagttccttcctttatgcaagaagga gcaatttttgacagatatgaagaggaatcctttgtgtttgaacccaactgcctcttcaaa gtggatgaatttggcttctttctgacctggaaaagcgaaggcaaggaaggacaagtgcta gaatgctccctcatcaacagcattcggttgggagccacaccaaaggaccccaaaatcctg gctgctctcgaagctgttggaaaatcagaaaatgatctggaagggcggatactttgtgtc tgcagcggtacagacctggtgaacatcagtttcacttacatggtggccgaaaatccagac gtaactaagcaatgggtagacggcctgagatccatcatacacaacttcagggccaacaac gtcagtccgatgacctgcctcaagaaacactggatgaaattggcatttatgaccaacaca aatggcaaaattccagtgaggagtattactagaacctttgcatcggggaagacagaaaag gtgatctttcaagcactcaaggagttaggtcttcccagcggaaagaatgatgaaatcgag cctgcagcatttacttacgaaaagttctatgaactgacacaaaagatttgtcctcggaca gatatagaggatctttttaaaaaaatcaatggagacaaaactgattatttaacggtagac caattagtgagctttctaaatgaacatcaacgagatcctcgactcaatgaaattttattc ccattttatgatgctaaaagggcaatgcagatcattgagatgtatgagcctgatgaagac ttgaagaaaaaaggccttatatccagtgatggattttgcagatatctgatgtcagatgaa aacgcccccgtcttcctagatcgtttagaactttaccaagaaatggaccatcctctggct cactacttcatcagttcttcccacaacacctatctcactggccgacagttcggcgggaag tcttcggtagaaatgtacagacaggtcctcctggctggctgcagatgtgtcgaacttgac tgttgggatggaaaaggtgaagaccaagaaccgataatcactcatggaaaagcaatgtgt acagatatcctttttaaggatgttattcaagccatcaaggaaacggcatttgtcacatct gaatatcctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg tccaaatattgcgaagatctatttggggatctcctgttgaaacaagcacttgaatcacat ccacttgaaccaggcaggcccttgccatcccccaatgacctcaaaagaaaaatactcatc aaaaataaacggctgaaacctgaggttgaacaaaagcagctcgaagctttgaaaagcatg atggaagctggagaatctgctgctccagttagcatcttagaggatgataatgaggagtga atagaaagtgttgaccaagaggaagaagctcatcctgaatacaaatttggaagcgaactt gatgacttgggtcacaaggaagttgttgcaaatagtgtcaagaaggtttctgatgacctt gaacatgaaaacaacaaaaagggcctggttaccgtagaagatgagcaggcatggatggca tcttataaatatgtaggtgctaccactaatatccacccgtatttgtccacaatgatcaac tatgcacagccggtaaagtttcaaggtttccatgtggctgaagaacgcaacattcattat aacatgtcttcttttaacgagtcagtcggtctaggctacttgaagacacatgcgattgaa tttgtgaattataacaaaaggcaaatgagtcgtatttaccccaagggaggccgagtggat tccagtaattacatgcctcagattttctggaacgctggctgccagatggtttcactgaac tatcaaaccccagatttagcgatgcaattgaatcagggaaaatttgagtataatggatcg tgcgggtaccttctcaaaccagatttcatgagacggcctgatcgaacatttgatcctttc tctgagactcctgttgacggggtgatagcagccacttgctcagtgcaggtcatatcaggt cagttcttatcagataagaaaattggcacatacgtagaagtggatatgtatgggttgccc actgacactatacgtaaggaattccgaactcgcatggtgatgaacaacggactcaatcca gtttacaatgaagaatcattcgtgtttcggaaggtaatcctccctgacctggcagtcttg aggatagcagtgtacgatgacaacaacaggctgatcggccagaggattctcccactggat ggcctccaagcaggctatcgacacatatcccttcgaaatgagggaaataaaccattatca ctgccaacaattttctgcaatattgtgcttaaaacatatgtgcctgatggatttggagat attgtggatgctttatcagatccaaagaagtttctttcaattacggaaaaaagagcagac caaatgagagctatgggcattgaaactagtgacatagctgatgtgcccagcgacacgtct aagaatgacaagaaaggaaaggccaacactgccaaaacaaatgtgaccccgcagagcagc tcagagctcagaccaaccaccacagccgccctggggtccggcatggaagccaagaaaggt attgaacttatccctcaagtgaggatagaagatttaaagcagatgaaggcttacttgaag catttaaagaaacagcagaaggagctaaattctttaaagaagaagcatgcaaaggagcac agcaccatgcagaagctacactgcacgcaagttgacaaaattgtggcacagtatgacaaa gagaagtcaacccatgagaaaatcctagagaaggcaatgaagaagaaggggggaagtaat tgtcttgaaatgaaaaaagaaacagaaattaaaattcagacattgacatcagatcacaaa tctaaggtcaaagagattgtggcgcagcacacaaaggagtggtcagaaatgatcaacacc cacagtgccgaggagcaggaaatccgggacctgcacctcagccagcagtgtgagctgctg aggaagctcctgatcaacgcccacgaacagcaaacccagcagctgaaactgtcccacgac agggaaagcaaggaaatgagagcacaccaggctaagatttctatggaaaatagcaaagcc atcagccaagacaaatctatcaagaacaaagcagaacgggaaaggcgagtcagggagtta aacagcagcaacactaaaaagtttctggaagaaagaaagagactcgcaatgaaacaatcc aaagaaatggatcagttgaaaaaagtccagcttgaacacctagaattcctagagaaacag aatgagcagcttttgaaatcctgtcacgcagtgtcccaaactcaaggcgaaggagatgca gcagatggtgaaattggaagccgagatggaccgcagaccagcaacagttgtatgaaactc cagaacacaaactga

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